Search Results - "Clark, Wayne M."

Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis by Brott, Thomas G, Howard, George, Roubin, Gary S, Meschia, James F, Mackey, Ariane, Brooks, William, Moore, Wesley S, Hill, Michael D, Mantese, Vito A, Clark, Wayne M, Timaran, Carlos H, Heck, Donald, Leimgruber, Pierre P, Sheffet, Alice J, Howard, Virginia J, Chaturvedi, Seemant, Lal, Brajesh K, Voeks, Jenifer H, Hobson, Robert W

“…In this long-term follow-up of a randomized trial comparing endarterectomy with stenting for carotid-artery stenosis, the risks of periprocedural stroke,…”
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Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial by Hess, David C, Prof, Wechsler, Lawrence R, Prof, Clark, Wayne M, Prof, Savitz, Sean I, Prof, Ford, Gary A, Prof, Chiu, David, Prof, Yavagal, Dileep R, Prof, Uchino, Ken, Prof, Liebeskind, David S, Prof, Auchus, Alexander P, Prof, Sen, Souvik, Prof, Sila, Cathy A, Prof, Vest, Jeffrey D, PhD, Mays, Robert W, PhD

“…Summary Background Multipotent adult progenitor cells are a bone marrow-derived, allogeneic, cell therapy product that modulates the immune system, and…”
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Safety of Stenting and Endarterectomy by Symptomatic Status in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) by SILVER, Frank L, MACKEY, Ariane, HOWARD, George, BROTT, Thomas G, CLARK, Wayne M, BROOKS, William, TIMARAN, Carlos H, CHIU, David, GOLDSTEIN, Larry B, MESCHIA, James F, FERGUSON, Robert D, MOORE, Wesley S

“…The safety of carotid artery stenting (CAS) and carotid endarterectomy (CEA) has varied by symptomatic status in previous trials. The Carotid Revascularization…”
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Stroke After Carotid Stenting and Endarterectomy in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) by HILL, Michael D, BROOKS, William, LONGBOTTOM, Mary E, VOEKS, Jenifer H, HOWARD, George, BROTT, Thomas G, MACKEY, Ariane, CLARK, Wayne M, MESCHIA, James F, MORRISH, William F, MOHR, J. P, RHODES, J. David, POPMA, Jeffrey J, LAL, Brajesh K

“…Stroke occurs more commonly after carotid artery stenting than after carotid endarterectomy. Details regarding stroke type, severity, and characteristics have…”
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Differential effect of gold nanoparticles on cerebrovascular function and biomechanical properties by Hunt, Ryan D., Sedighi, Omid, Clark, Wayne M., Doiron, Amber L., Cipolla, Marilyn J.

“…Human stroke serum (HSS) has been shown to impair cerebrovascular function, likely by factors released into the circulation after ischemia. 20 nm gold…”
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Intracranial hemorrhage complicating carotid artery stenting and carotid endarterectomy by Clark, Wayne M, Brott, Thomas G

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The use of flow cytometry to evaluate temporal changes in inflammatory cells following focal cerebral ischemia in mice by Stevens, Susan L, Bao, Jianzhong, Hollis, Jacob, Lessov, Nikola S, Clark, Wayne M, Stenzel-Poore, Mary P

“…Recent studies indicate that inflammation following cerebral ischemia contributes to neuronal damage. The local activation of resident cells and efficient…”
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Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke by Broderick, Joseph P, Palesch, Yuko Y, Demchuk, Andrew M, Yeatts, Sharon D, Khatri, Pooja, Hill, Michael D, Jauch, Edward C, Jovin, Tudor G, Yan, Bernard, Silver, Frank L, von Kummer, Rüdiger, Molina, Carlos A, Demaerschalk, Bart M, Budzik, Ronald, Clark, Wayne M, Zaidat, Osama O, Malisch, Tim W, Goyal, Mayank, Schonewille, Wouter J, Mazighi, Mikael, Engelter, Stefan T, Anderson, Craig, Spilker, Judith, Carrozzella, Janice, Ryckborst, Karla J, Janis, L. Scott, Martin, Renée H, Foster, Lydia D, Tomsick, Thomas A

“…In this randomized trial involving patients with acute ischemic stroke, endovascular therapy after the administration of intravenous tissue plasminogen…”
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Meta-analysis of randomized intra-arterial thrombolytic trials for the treatment of acute stroke due to middle cerebral artery occlusion by Fields, Jeremy D, Khatri, Pooja, Nesbit, Gary M, Liu, Kenneth C, Barnwell, Stanley L, Lutsep, Helmi L, Clark, Wayne M, Lansberg, Maarten G

“…Randomized clinical trials supporting the use of intra-arterial administration of thrombolytics (IAT) for the treatment of stroke due to middle cerebral artery…”
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Tenecteplase for Stroke at 4.5 to 24 Hours with Perfusion-Imaging Selection by Albers, Gregory W., Jumaa, Mouhammad, Purdon, Barbara, Zaidi, Syed F., Streib, Christopher, Shuaib, Ashfaq, Sangha, Navdeep, Kim, Minjee, Froehler, Michael T., Schwartz, Neil E., Clark, Wayne M., Kircher, Charles E., Yang, Ming, Massaro, Lori, Lu, Xiao-Yu, Rippon, Gregory A., Broderick, Joseph P., Butcher, Ken, Lansberg, Maarten G., Liebeskind, David S., Nouh, Amre, Schwamm, Lee H., Campbell, Bruce C.V.

“…Tenecteplase for thrombolysis in a 4.5-to-24-hour window did not improve disability outcomes at 90 days in patients with ischemic stroke who had been chosen on…”
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High-Density Lipoprotein Carries Markers That Track With Recovery From Stroke by Plubell, Deanna L., Fenton, Alex M., Rosario, Sara, Bergstrom, Paige, Wilmarth, Phillip A., Clark, Wayne M., Zakai, Neil A., Quinn, Joseph F., Minnier, Jessica, Alkayed, Nabil J., Fazio, Sergio, Pamir, Nathalie

“…RATIONALE:Prospective cohort studies question the value of HDL-C for stroke risk prediction. OBJECTIVE:Investigate the relationship between long-term…”
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Efficacy of antioxidant therapies in transient focal ischemia in mice by CLARK, Wayne M, RINKER, Lisa G, LESSOV, Nikola S, LOWERY, Stuart L, CIPOLLA, Marilyn J

“…Ginkgo biloba extract (EGb) and alpha-lipoic acid (LA) are commercially available "antioxidant supplements" with a variety of actions that may be beneficial…”
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Stenting versus Endarterectomy for Treatment of Carotid-Artery Stenosis by Brott, Thomas G, Hobson, Robert W, Howard, George, Howard, Virginia J, Roubin, Gary S, Clark, Wayne M, Brooks, William, Mackey, Ariane, Hill, Michael D, Leimgruber, Pierre P, Sheffet, Alice J, Moore, Wesley S, Voeks, Jenifer H, Hopkins, L. Nelson, Cutlip, Donald E, Cohen, Stanley N, Cohen, David J, Popma, Jeffrey J, Ferguson, Robert D, Blackshear, Joseph L, Silver, Frank L, Mohr, J.P, Lal, Brajesh K, Meschia, James F

“…In this randomized comparison of stenting and endarterectomy as treatment for carotid-artery stenosis, there was no significant difference in the rate of the…”
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Baseline Cognitive Impairment in Patients With Asymptomatic Carotid Stenosis in the CREST-2 Trial by Lazar, Ronald M., Wadley, Virginia G., Myers, Terina, Jones, Michael R., Heck, Donald V., Clark, Wayne M., Marshall, Randolph S., Howard, Virginia J., Voeks, Jenifer H., Manly, Jennifer J., Moy, Claudia S., Chaturvedi, Seemant, Meschia, James F., Lal, Brajesh K., Brott, Thomas G., Howard, George

“…Studies of carotid artery disease have suggested that high-grade stenosis can affect cognition, even without stroke. The presence and degree of cognitive…”
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Minocycline to Improve Neurologic Outcome in Stroke (MINOS): A Dose-Finding Study by FAGAN, Susan C, WALLER, Jennifer L, NICHOLS, Fenwick T, EDWARDS, David J, CREED PETTIGREW, L, CLARK, Wayne M, HALL, Christiana E, SWITZER, Jeffrey A, ERGUL, Adviye, HESS, David C

“…Minocycline is a promising anti-inflammatory and protease inhibitor that is effective in multiple preclinical stroke models. We conducted an early phase trial…”
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Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial by Hill, Michael D, Prof, Martin, Renee H, PhD, Mikulis, David, Prof, Wong, John H, MD, Silver, Frank L, Prof, terBrugge, Karel G, Prof, Milot, Geneviève, Prof, Clark, Wayne M, Prof, MacDonald, R Loch, Prof, Kelly, Michael E, MD, Boulton, Melford, MD, Fleetwood, Ian, MD, McDougall, Cameron, Prof, Gunnarsson, Thorsteinn, MD, Chow, Michael, MD, Lum, Cheemun, MD, Dodd, Robert, MD, Poublanc, Julien, MSc, Krings, Timo, Prof, Demchuk, Andrew M, Prof, Goyal, Mayank, Prof, Anderson, Roberta, PhD, Bishop, Julie, MA, Garman, David, PhD, Tymianski, Michael, Prof

“…Summary Background Neuroprotection with NA-1 (Tat-NR2B9c), an inhibitor of postsynaptic density-95 protein, has been shown in a primate model of stroke. We…”
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Health-Related Quality of Life After Carotid Stenting Versus Carotid Endarterectomy: Results From CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) by COHEN, David J, STOLKER, Joshua M, GOLDSTEIN, Larry B, ROUBIN, Gary S, HOWARD, George, BROTT, Thomas G, KAIJUN WANG, MAGNUSON, Elizabeth A, CLARK, Wayne M, DEMAERSCHALK, Bart M, SAM, Albert D, ELMORE, James R, WEAVER, Fred A, ARONOW, Herbert D

“…The purpose of this study was to compare health-related quality of life (HRQOL) outcomes in patients treated with carotid artery stenting (CAS) versus carotid…”
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Matrix Metalloproteinase-9 in an Exploratory Trial of Intravenous Minocycline for Acute Ischemic Stroke by SWITZER, Jeffrey A, HESS, David C, ERGUL, Adviye, WALLER, Jennifer L, MACHADO, Livia S, PORTIK-DOBOS, Vera, CREED PETTIGREW, L, CLARK, Wayne M, FAGAN, Susan C

“…Plasma matrix metalloproteinase-9 levels predict posttissue plasminogen activator (tPA) hemorrhage. The authors investigated the effect of minocycline on…”
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Keep the Three Hour TPA Window: The Lost Study of Atlantis by Clark, Wayne M., MD, Madden, Kenneth P., MD, PhD

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Efficacy of citicoline as an acute stroke treatment by Clark, Wayne M

“…Citicoline (cytidine-5'-diphosphocholine or CDP-choline) is a precursor essential for the synthesis of phosphatidylcholine, one of the cell membrane components…”
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