Search Results - "Clark, R.D."

Tolerance to 3,4-methylenedioxymethamphetamine in rats exposed to single high-dose binges by Baumann, M.H, Clark, R.D, Franken, F.H, Rutter, J.J, Rothman, R.B

“…Abstract 3,4-Methylenedioxymethamphetamine (MDMA or ecstasy) stimulates the transporter-mediated release of monoamines, including 5-HT. High-dose exposure to…”
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CASA and LEAD: adaptive cyberinfrastructure for real-time multiscale weather forecasting by Plale, B., Gannon, D., Brotzge, J., Droegemeier, K., Kurose, J., McLaughlin, D., Wilhelmson, R., Graves, S., Mohan Ramamurthy, Clark, R.D., Yalda, S., Reed, D.A., Joseph, E., Chandrasekar, V.

“…Two closely linked projects aim to dramatically improve storm forecasting speed and accuracy. CASA is creating a distributed, collaborative, adaptive sensor…”
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The effects of novel, selective 5-hydroxytryptamine (5-HT)4 receptor ligands in rat spatial navigation by Fontana, D J, Daniels, S E, Wong, E H, Clark, R D, Eglen, R M

“…Activation of central 5-hydroxytryptamine (5-HT4) receptors may enhance cognitive performance. In the present study, the effects of two novel, potent and…”
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Pharmacological characterization of two novel and potent 5‐HT4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo by Eglen, R.M., Bonhaus, D.W., Johnson, L.G., Leung, E., Clark, R.D.

“…1 The pharmacology of two novel 5‐HT4 receptor agonists, RS 67333 (1‐(4‐amino‐5‐chloro‐2‐methoxy phenyl)‐3‐[1(n‐butyl)‐4‐piperidinyl]‐1‐propanone HC1) and RS…”
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RS 39604: a potent, selective and orally active 5‐HT4 receptor antagonist by Hegde, S.S., Bonhaus, D.W., Johnson, L.G., Leung, E., Clark, R.D., Eglen, R.M.

“…1 Selective antagonism of 5‐HT4 receptors may provide therapeutic benefit in certain disorders of the myocardium, alimentary and lower urinary tract. We now…”
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Evaluation of QSAR models for predicting mutagenicity: outcome of the Second Ames/QSAR international challenge project by Furuhama, A., Kitazawa, A., Yao, J., Matos dos Santos, C.E., Rathman, J., Yang, C., Ribeiro, J.V., Cross, K., Myatt, G., Raitano, G., Benfenati, E., Jeliazkova, N., Saiakhov, R., Chakravarti, S., Foster, R.S., Bossa, C., Battistelli, C. Laura, Benigni, R., Sawada, T., Wasada, H., Hashimoto, T., Wu, M., Barzilay, R., Daga, P.R., Clark, R.D., Mestres, J., Montero, A., Gregori-Puigjané, E., Petkov, P., Ivanova, H., Mekenyan, O., Matthews, S., Guan, D., Spicer, J., Lui, R., Uesawa, Y., Kurosaki, K., Matsuzaka, Y., Sasaki, S., Cronin, M.T.D., Belfield, S.J., Firman, J.W., Spînu, N., Qiu, M., Keca, J.M., Gini, G., Li, T., Tong, W., Hong, H., Liu, Z., Igarashi, Y., Yamada, H., Sugiyama, K.-I., Honma, M.

“…Quantitative structure−activity relationship (QSAR) models are powerful in silico tools for predicting the mutagenicity of unstable compounds, impurities and…”
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RS 23597‐190: a potent and selective 5‐HT4 receptor antagonist by Eglen, R.M., Bley, K., Bonhaus, D.W., Clark, R.D., Hegde, S.S., Johnson, L.G., Leung, E., Wong, E.H.F.

“…1 The pharmacological properties of RS 23597‐190 (3‐(piperdine‐1‐yl)‐propyl‐4‐amino‐5‐chloro‐2‐methoxy benzoate hydrochloride) have been studied in vitro and…”
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A spatially constrained clustering program for river valley segment delineation from GIS digital river networks by Brenden, T.O., Wang, L., Seelbach, P.W., Clark, R.D., Wiley, M.J., Sparks-Jackson, B.L.

“…River valley segments are adjacent sections of streams and rivers that are relatively homogeneous in hydrology, limnology, channel morphology, riparian…”
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Modified RP4 and Tn5-Mob derivatives for facilitated manipulation of large plasmids in Gram-negative bacteria by Quandt, Jürgen, Clark, Rhonda G, Venter, Alexandra P, Clark, Scott R.D, Twelker, Sunny, Hynes, Michael F

“…We have constructed a set of RP4 (Nm super(S)/Tc super(S)) and Tn5-Mob derivatives which have applications in experiments involving mobilization of replicons…”
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Array Comparative Genome Hybridization Identifies Chromosomal Origins of Two Marker Chromosomes from 11Q and 17P: The First Report of a Patient with Two Different Marker Chromosomes by Clark, R.D., Demos, D.S., Shaffer, L.G.

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Apparent Triplication of Distal 1Q in a Child with Developmental Delay and Congenital Anomalies: The First Case of Tetrsomy 1Q42–44 by Clark, R.D., Curry, C.J., Drumheller, T.C.

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The glcB locus of Rhizobium leguminosarum VF39 encodes an arabinose-inducible malate synthase by García-de los Santos, Alejandro, Morales, Alejandro, Baldomá, Laura, Clark, Scott R D, Brom, Susana, Yost, Christopher K, Hernández-Lucas, Ismael, Aguilar, Juan, Hynes, Michael F

“…In the course of a study conducted to isolate genes upregulated by plant cell wall sugars, we identified an arabinose-inducible locus from a transcriptional…”
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Characterization of the light-driven sodium pump of Halobacterium halobium. Consequences of sodium efflux as the primary light-driven event by MacDonald, R E, Greene, R V, Clark, R D, Lindley, E V

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Delineation of Two Subtle Chromosome Duplications, 4P16 and 22Q11.2, in a Three-Generation Family with Mental Retardation by Fluorescent in Situ Hybridization and Array Comparative Genomic Hybridization by Curry, C.J., Cotter, P.D., Roeder, E.R., Delozier, C.D., Clark, R.D., Drumheller, T., Rauen, K.A.

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class IId bacteriocin thuricin-17 increases plant growth by Lee, Kyung Dong, Gray, Elizabeth J, Mabood, Fazli, Jung, Woo-Jin, Charles, Trevor, Clark, Scott R. D, Ly, Anh, Souleimanov, Alfred, Zhou, Xiaomin, Smith, Donald Lawrence

“…The mechanisms by which many plant growth promoting rhizobacteria (PGPR) affect plants are unknown. We recently isolated a rhizosphere bacterium (Bacillus…”
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Synthesis and QSAR of herbicide 3-pyrazolyl alpha,alpha,alpha-trifluorotolyl ethers by Clark, R.D. (Tripos, Inc., St. Louis, MO.)

“…Pyrazole nitrophenyl ethers (PPEs) were recently identified as a novel class of chemistry exerting herbicidal effects by inhibition of protoporphyrinogen IX…”
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Molecular modeling and experimental study of non-linear optical compounds: monosubstituted derivatives of dicyanovinylbenzene by Timofeeva, T.V., Nesterov, V.N., Antipin, M.Yu, Clark, R.D., Sanghadasa, M., Cardelino, B.H., Moore, C.E., Frazier, D.O.

“…A search for potential non-linear optical (NLO) compounds has been performed using the Cambridge Structural Database and molecular modeling. We have studied a…”
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Pharmacological characterization of two novel and potent 5‐HT 4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo by Eglen, R.M., Bonhaus, D.W., Johnson, L.G., Leung, E., Clark, R.D.

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Identification and characterization of the intracellular poly-3-hydroxybutyrate depolymerase enzyme PhaZ of Sinorhizobium meliloti by Trainer, Maria A, Capstick, David, Zachertowska, Alicja, Lam, Kathy N, Clark, Scott R D, Charles, Trevor C

“…S. meliloti forms indeterminate nodules on the roots of its host plant alfalfa (Medicago sativa). Bacteroids of indeterminate nodules are terminally…”
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Green and red fluorescent protein vectors for use in biofilm studies of the intrinsically resistant Burkholderia cepacia complex by Tomlin, Kerry L., Clark, Scott R.D., Ceri, Howard

“…Cystic fibrosis isolates of the Burkholderia cepacia complex (BCC) have demonstrated a propensity to associate intimately with Pseudomonas aeruginosa in mixed…”
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