Search Results - "Clark, Penelope M.S"

Preanalytical, Analytical, and Computational Factors Affect Homeostasis Model Assessment Estimates by Manley, Susan E, Luzio, Stephen D, Stratton, Irene M, Wallace, Tara M, Clark, Penelope M.S

“…OBJECTIVE:--We investigated how β-cell function and insulin sensitivity or resistance are affected by the type of blood sample collected or choice of insulin…”
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Measurement of proinsulin and intermediates : validation of immunoassay methods by high-performance liquid chromatography by OSTREGA, D, POLONSKY, K, DINESH NAGI, YUDKIN, J, COX, L. J, CLARK, P. M. S, HALES, C. N

“…Human proinsulin and 32-33 split proinsulin have been measured in the peripheral circulation by immunoradiometric assays (IRMAs) and have been shown to be…”
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Influence of thyroid hormone autoantibodies on 7 thyroid hormone assays by Zouwail, Soha A, O'Toole, Angela M, Clark, Penelope M S, Begley, Joe P

“…Spurious results of thyroid function tests (TFT) can be recognized when they do not reflect the clinical status of the patient or are not internally consistent…”
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Radioimmunoassay may overestimate insulin in non-insulin-dependent diabetics by Temple, R C, Clark, P M, Nagi, D K, Schneider, A E, Yudkin, J S, Hales, C N

“…We have compared insulin concentrations measured by radioimmunoassay (RIA) in plasma from 50 fasting non-insulin-dependent diabetics (NIDDM) with those…”
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Raised proinsulin concentration as early indicator of β cell dysfunction by WILLIAMS, D. R. R, BYRNE, C, CLARK, P. M. S, COX, L, DAY, N. E, RAYMAN, G, WANG, T, HALES, C. N

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Abnormalities of thyrotrophin (TSH) evening rise and pulsatile release in haemodialysis patients: evidence for hypothalamic-pituitary changes in chronic renal failure by Wheatley, T, Clark, P M, Clark, J D, Holder, R, Raggatt, P R, Evans, D B

“…Using a sensitive enzyme amplified immunoassay for TSH, the evening rise and pulsatile release of TSH were studied in 10 men with chronic renal failure treated…”
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Effects of octreotide on circulating islet B cell products in endogenous hyperinsulinism by Krentz, A. J., Pace, J., Somerville, W., Clark, P. M., Nattrass, M.

“…The role of somatostatin analogues in the medical management of insulinomas is unclear. We describe an elderly patient with clinical and biochemical features…”
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Insulin and proinsulin-like molecules in motor neurone disease by Krentz, A J, Clark, P M, Cox, L, Williams, A C, Nattrass, M

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Potential applications and pitfalls of dry reagent tests. An evaluation of the Ames Seralyzer by Clark, P M, Broughton, P M

“…In recent years, the development of dry reagent tests has made it possible for many clinical laboratory tests to be performed not only in the laboratory but…”
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Matrix effects in clinical analysis: commutability of control materials between the Ektachem, Beckman and SMA 12/60 glucose and urea methods by Clark, P M, Kricka, L J, Whitehead, T P

“…The effects of the protein matrices of selected human and animal based control materials on the Ektachem, Beckman and SMA 12/60 glucose and urea methods have…”
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Instrumentation by Broughton, P M, Carter, T J, Clark, P M

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Comparison of urinary excretion of UV-absorbing constituents in healthy subjects and patients with rheumatoid arthritis using analytical isotachophoresis by Clark, P M, Kricka, L J, Whitehead, T P

“…Analytical isotachophoresis has been applied to the separation of urinary constituents in healthy controls and patients with rheumatoid and osteoarthritis…”
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Ultrathinfilm immunoelectrophoresis by Michiak, A, Clark, P M, Kricka, L J

“…Immunoelectrophoresis (Laurell-rocket) in ultrathinfilm gels has been applied to the determination of human serum albumin in a model study. Agarose gels of…”
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Effects of storage on serum apolipoprotein polymorphs using the Iso-Dalt technique by Gomo, R A, Clark, P M, Kricka, L J, Whitehead, T P

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Characterisation of the protein matrix of quality control sera by a high resolution two-dimensional electrophoresis technique by Clark, P M, Kricka, L J, Gomo, A R, Whitehead, T P, Bullock, D G, Saidi, H

“…A high resolution two-dimensional electrophoresis technique (Iso-Dalt) has been employed to characterise the protein components of freshly drawn human serum…”
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