Search Results - "Clark, K R"

Plasmapheresis Eliminates the Negative Impact of AAV Antibodies on Microdystrophin Gene Expression Following Vascular Delivery by Chicoine, LG, Montgomery, CL, Bremer, WG, Shontz, KM, Griffin, DA, Heller, KN, Lewis, S, Malik, V, Grose, WE, Shilling, CJ, Campbell, KJ, Preston, TJ, Coley, BD, Martin, PT, Walker, CM, Clark, KR, Sahenk, Z, Mendell, JR, Rodino-Klapac, LR

“…Duchenne muscular dystrophy is a monogenic disease potentially treatable by gene replacement. Use of recombinant adeno-associated virus (AAV) will ultimately…”
Get full text

Recombinant AAV serotype 1 transduction efficiency and tropism in the murine brain by WANG, C, WANG, C.-M, CLARK, K. R, SFERRA, T. J

“…Recombinant adeno-associated virus serotype 2 (rAAV2) vectors have shown promise as therapeutic agents for neurologic disorders. However, intracerebral…”
Get full text

Denture identification marking should be standard practice by Kalyan, A., Clark, R. K. F., Radford, D. R.

“…Key Points Stresses that denture identification marking helps prevent loss of dentures in care home and hospital settings. Literature shows that when asked,…”
Get full text

Lack of toxicity of alpha-sarcoglycan overexpression supports clinical gene transfer trial in LGMD2D by RODINO-KLAPAC, L. R, LEE, J.-S, MULLIGAN, R. C, CLARK, K. R, MENDELL, J. R

“…Alpha-sarcoglycan (alpha-SG) deficiency (limb-girdle muscular dystrophy [LGMD] type 2D) is the most common form of sarcoglycan-LGMD. No treatment is currently…”
Get full text

Redox Regulation of Vascular Smooth Muscle Cell Differentiation by Su, B, Mitra, S, Gregg, H, Flavahan, S, Chotani, M A, Clark, K R, Goldschmidt-Clermont, P J, Flavahan, N A

“…ABSTRACT—Experiments were performed to determine the role of reactive oxygen species (ROS) in regulating vascular smooth muscle cell (VSMC) phenotype. After…”
Get full text

Current trends in complete denture teaching in British dental schools by Clark, R. K. F, Radford, D. R, Juszczyk, A. S

“…Key Points Concern is raised that GDC requirements laid out in 'The First Five Years' for competency in complete denture construction are not being met. The…”
Get full text

Tumor necrosis factor-alpha expression in ischemic neurons by Liu, T, Clark, R K, McDonnell, P C, Young, P R, White, R F, Barone, F C, Feuerstein, G Z

“…Tumor necrosis factor-alpha (TNF-alpha) is a cytokine with diverse proinflammatory actions, including endothelial leukocyte adhesion molecule expression. Since…”
Get full text

The retentive forces of the locator attachment system at different angulations by Stergiou, A, Juszczyk, A S, Clark, R K F, Radford, D R

“…The change of retentive force of three types of Locator inserts when the implant analogue was positioned perpendicular to horizontal, 5 degrees and 10 degrees…”
Get more information

UK dental laboratory technicians' views on the efficacy and teaching of clinical-laboratory communication by Juszczyk, A. S, Clark, R. K. F, Radford, D. R

“…Key Points Dental laboratory technicians consider newly qualified dentists to have a poor understanding of dental technical procedures and techniques. Dental…”
Get full text

Development and evaluation of an illustrated paediatric leaflet ‘Coming to Hospital: a guide to what goes on’ by Clark, Elisha K R, Sanghavi, Sanjana S, Farrell, Stephen, Fritz, Zoë

“…BackgroundA paediatric information leaflet was produced to better prepare patients for time spent in hospital and to improve experience by informing them what…”
Get full text

Generation of an LFA-1 Antagonist by the Transfer of the ICAM-1 Immunoregulatory Epitope to a Small Molecule by Gadek, T. R., Burdick, D. J., McDowell, R. S., Stanley, M. S., Marsters, J. C., Paris, K. J., Oare, D. A., Reynolds, M. E., Ladner, C., Zioncheck, K. A., Lee, W. P., Gribling, P., Dennis, M. S., Skelton, N. J., Tumas, D. B., Clark, K. R., Keating, S. M., Beresini, M. H., Tilley, J. W., Presta, L. G., Bodary, S. C.

“…The protein-protein interaction between leukocyte functional antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1) is critical to lymphocyte and…”
Get full text

Production of recombinant adeno-associated virus vectors using a packaging cell line and a hybrid recombinant adenovirus by LIU, X. L, CLARK, K. R, JOHNSON, P. R

“…Recombinant adeno-associated virus (rAAV) vectors are under consideration for a wide variety of gene therapy applications. One of the limitations of the rAAV…”
Get full text

Effect of welding parameters of the Nd:YAG laser on the penetration depth of cobalt chromium alloys by Vlachogianni, V, Clark, R K F, Juszczyk, A S, Radford, D R

“…The aim of the investigation was to study the effect of the laser welding parameters of energy and spot diameter on the penetration depth of the weld of cast…”
Get more information

The effect of monomer/polymer mixing ratio, time between mixing and packing of heat cured acrylic resin denture base material and bond assisting agents on the bond strength to acrylic resin denture teeth by Alshahrani, A M, Spithourakis, S A, Juszczyk, A S, Radford, D R, Clark, R K F

“…The aim of the study was to investigate the effect of varying the monomer/polymer mixing ratio, the time from mixing to packing heat cured acrylic resin and…”
Get more information

Adeno-associated virus-mediated delivery of BCL-w gene improves outcome after transient focal cerebral ischemia by SUN, Y, JIN, K, CLARK, K. R, PEEL, A, MAO, X. O, CHANG, Q, SIMON, R. P, GREENBERG, D. A

“…A recombinant adeno-associated virus (rAAV) vector was used to overexpress the anti-apoptotic Bcl-2-family protein, BCL-w, in rat brain. Three weeks after…”
Get full text

Flexural strength and degree of polymerization of a proprietary denture base acrylic resin designed to be cured using long or short cycles by Bentaher, H A, Juszczyk, A S, Deb, S, Clark, R K F, Radford, D R

“…The flexural strength and degree of polymerization of Diamond D acrylic resin prepared with a long cure monomer and a short cure monomer were investigated…”
Get more information

Cell lines for the production of recombinant adeno-associated virus by Clark, K R, Voulgaropoulou, F, Fraley, D M, Johnson, P R

“…Adeno-associated virus (AAV) is a replication-defective parvovirus that is being developed as a vector for human gene transfer. However, a major obstacle to…”
Get more information

Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses by Clark, K R, Liu, X, McGrath, J P, Johnson, P R

“…Gene transfer vectors based on the replication-defective human parvovirus, adeno-associated virus type 2 (AAV-2), are viable candidates for in vivo and ex vivo…”
Get more information

Effect of curing cycles on the mechanical properties of heat cured acrylic resins by Athar, Z, Juszczyk, A S, Radford, D R, Clark, R K F

“…Traditionally long curing cycles have been recommended for heat cured acrylic resin denture base materials. Recently manufacturers have produced materials for…”
Get more information

Polymorphonuclear leukocyte infiltration into cerebral focal ischemic tissue: myeloperoxidase activity assay and histologic verification by Barone, F C, Hillegass, L M, Price, W J, White, R F, Lee, E V, Feuerstein, G Z, Sarau, H M, Clark, R K, Griswold, D E

“…Two different techniques were utilized to identify the infiltration of polymorphonuclear leukocytes (PMN) into cerebral tissue following focal ischemia:…”
Get more information