Search Results - "Clark, Gregory O"
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Leptin therapy in insulin-deficient type I diabetes
Published in Proceedings of the National Academy of Sciences - PNAS (16-03-2010)“…In nonobese diabetic mice with uncontrolled type 1 diabetes, leptin therapy alone or combined with low-dose insulin reverses the catabolic state through…”
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Journal Article -
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Type 1 Diabetes Treatment beyond Insulin: Role of GLP-1 Analogs
Published in Journal of investigative medicine (01-01-2013)“…Objective To observe the efficacy and safety of glucagonlike peptide-1 (GLP-1) analogs in type 1 diabetes in a real-life medical practice setting. Methods We…”
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Efficacy and Safety of Metreleptin Therapy in Patients With Type 1 Diabetes: A Pilot Study
Published in Diabetes care (01-05-2017)“…To study the efficacy and safety of metreleptin therapy in patients with suboptimally controlled type 1 diabetes mellitus (T1DM). After a baseline period of 4…”
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Lipid homeostasis, lipotoxicity and the metabolic syndrome
Published in Biochimica et biophysica acta (01-03-2010)“…In the 20th century industrialized nations have become afflicted with an unprecedented pandemic of increased adiposity. In the United States, the epicenter of…”
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Iatrogenic hyperinsulinemia in type 1 diabetes: Its effect on atherogenic risk markers
Published in Journal of diabetes and its complications (2013)“…Abstract Aims Insulin is lipogenic and may invoke inflammation. We wished to determine if well controlled human and mice with type 1 diabetes had iatrogenic…”
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Type 1 Diabetes Treatment Beyond Insulin
Published in Journal of investigative medicine (01-01-2013)“…ObjectiveTo observe the efficacy and safety of glucagonlike peptide-1 (GLP-1) analogs in type 1 diabetes in a real-life medical practice setting.MethodsWe…”
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Journal Article -
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Glucose responsive insulin production from human embryonic germ (EG) cell derivatives
Published in Biochemical and biophysical research communications (11-05-2007)“…Type 1 diabetes mellitus subjects millions to a daily burden of disease management, life threatening hypoglycemia and long-term complications such as…”
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Cell therapies for type 1 diabetes mellitus
Published in Expert opinion on biological therapy (01-03-2004)“…Type 1 diabetes is caused by autoimmune destruction of pancreatic beta-cells and is characterised by absolute insulin insufficiency. The monocellular nature of…”
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Chapter 28 - Derivation and Differentiation of Human Embryonic Germ Cells
Published in Handbook of Stem Cells (2013)Get full text
Book Chapter -
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Chapter 42 - Derivation and Differentiation of Human Embryonic Germ Cells
Published in Essentials of Stem Cell Biology (2009)“…Embryonic germ (EG) cells are pluripotent stem cells derived from primordial germ cells (PGCs) that arise in the late embryonic and early fetal period of…”
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Book Chapter