Search Results - "Clark, Erin A"

Pregnancy-Associated Death in Utah: Contribution of Drug-Induced Deaths by Smid, Marcela C, Stone, Nicole M, Baksh, Laurie, Debbink, Michelle P, Einerson, Brett D, Varner, Michael W, Gordon, Adam J, Clark, Erin A S

“…Drug-induced deaths, defined as intentional or unintentional consumption of illicit substances or diverted medications leading to death, are the leading cause…”
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The heritability of gestational age in a two-million member cohort: implications for spontaneous preterm birth by Wu, Wilfred, Witherspoon, David J., Fraser, Alison, Clark, Erin A. S., Rogers, Alan, Stoddard, Gregory J., Manuck, Tracy A., Chen, Karin, Esplin, M. Sean, Smith, Ken R., Varner, Michael W., Jorde, Lynn B.

“…Preterm birth (PTB), defined as birth prior to a gestational age (GA) of 37 completed weeks, affects more than 10 % of births worldwide. PTB is the leading…”
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Early Second Trimester Maternal Serum Steroid-Related Biomarkers Associated with Autism Spectrum Disorder by Bilder, Deborah A., Esplin, M. Sean, Coon, Hilary, Burghardt, Paul, Clark, Erin A. S., Fraser, Alison, Smith, Ken R., Worsham, Whitney, Chappelle, Katlin, Rayner, Thomas, Bakian, Amanda V.

“…Epidemiologic studies link increased autism spectrum disorder (ASD) risk to obstetrical conditions associated with inflammation and steroid dysregulation,…”
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Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites by Yu, Tian, Campbell, Sarah C., Stockmann, Chris, Tak, Casey, Schoen, Katherine, Clark, Erin A. S., Varner, Michael W., Spigarelli, Michael G., Sherwin, Catherine M. T.

“…This study sought to assess the pharmacokinetic (PK) changes of caffeine and its CYP1A2 metabolites across the 3 trimesters of pregnancy. A prospective,…”
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LSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 Demethylation by Fang, Rui, Chen, Fei, Dong, Zhenghong, Hu, Di, Barbera, Andrew J., Clark, Erin A., Fang, Jian, Yang, Ying, Mei, Pinchao, Rutenberg, Michael, Li, Ze, Zhang, Ying, Xu, Youwei, Yang, Huirong, Wang, Ping, Simon, Matthew D., Zhou, Qiongjie, Li, Jing, Marynick, Mark P., Li, Xiaotian, Lu, Haojie, Kaiser, Ursula B., Kingston, Robert E., Xu, Yanhui, Shi, Yujiang Geno

“…Dynamic regulation of histone methylation represents a fundamental epigenetic mechanism underlying eukaryotic gene regulation, yet little is known about how…”
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GR and LSD1/KDM1A-Targeted Gene Activation Requires Selective H3K4me2 Demethylation at Enhancers by Clark, Erin A., Wu, Feizhen, Chen, Yirui, Kang, Paco, Kaiser, Ursula B., Fang, Rui, Shi, Yujiang G.

“…KDM1A-mediated H3K4 demethylation is a well-established mechanism underlying transcriptional gene repression, but its role in gene activation is less clear…”
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Cortical RORβ is required for layer 4 transcriptional identity and barrel integrity by Clark, Erin A, Rutlin, Michael, Capano, Lucia, Aviles, Samuel, Saadon, Jordan R, Taneja, Praveen, Zhang, Qiyu, Bullis, James B, Lauer, Timothy, Myers, Emma, Schulmann, Anton, Forrest, Douglas, Nelson, Sacha B

“…Retinoic acid-related orphan receptor beta (RORβ) is a transcription factor (TF) and marker of layer 4 (L4) neurons, which are distinctive both in…”
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Genetic predictors of severe intraventricular hemorrhage in extremely low-birthweight infants by Thornburg, Courtney D., Erickson, Stephen W., Page, Grier P., Clark, Erin A. S., DeAngelis, Margaret M., Hartnett, M. Elizabeth, Goldstein, Ricki F., Dagle, John M., Murray, Jeffrey C., Poindexter, Brenda B., Das, Abhik, Cotten, C. Michael

“…Objective To test associations between grades 3 or 4 (severe) intraventricular hemorrhage (IVH) and single nucleotide polymorphisms (SNPs) associated with…”
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Maternal prenatal weight gain and autism spectrum disorders by Bilder, Deborah A, Bakian, Amanda V, Viskochil, Joseph, Clark, Erin A S, Botts, Elizabeth L, Smith, Ken R, Pimentel, Richard, McMahon, William M, Coon, Hilary

“…The rising population of individuals identified with an autism spectrum disorder (ASD) calls for further investigation of its underlying etiology. A…”
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Correction: Genetic predictors of severe intraventricular hemorrhage in extremely low-birthweight infants by Thornburg, Courtney D., Erickson, Stephen W., Page, Grier P., Clark, Erin A. S., DeAngelis, Margaret M., Hartnett, M. Elizabeth, Goldstein, Ricki F., Dagle, John M., Murray, Jeffrey C., Poindexter, Brenda B., Das, Abhik, Cotten, C. Michael

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Maternal Magnesium Sulphate Exposure Predicts Neonatal Magnesium Blood Concentrations by Sherwin, Catherine M.T., Balch, Alfred, Campbell, Sarah C., Fredrickson, Jeunesse, Clark, Erin A.S., Varner, Michael, Stockmann, Chris, Korgenski, E. Kent, Bonkowsky, Joshua L., Spigarelli, Michael G.

“…Tocolytic use of magnesium sulphate is associated with excess neonatal mortality and has been proposed to follow a dose–response relationship. This study aimed…”
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Association of Polymorphisms in Neuroprotection and Oxidative Stress Genes and Neurodevelopmental Outcomes After Preterm Birth by Costantine, Maged M., Clark, Erin A. S., Lai, Yinglei, Rouse, Dwight J., Spong, Catherine Y., Mercer, Brian M., Sorokin, Yoram, Thorp, John M., Ramin, Susan M., Malone, Fergal D., Carpenter, Marshall, Miodovnik, Menachem, O'Sullivan, Mary J., Peaceman, Alan M., Caritis, Steve N.

“…To estimate the associations between polymorphisms in neuronal homeostasis, neuroprotection, and oxidative stress candidate genes and neurodevelopmental…”
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The association of innate immune response gene polymorphisms and puerperal group A streptococcal sepsis by Davis, Sarah M., MD, Clark, Erin A.S., MD, Nelson, Lesa T., MS, Silver, Robert M., MD

“…Objective The objective of the study was to determine whether single-nucleotide polymorphisms (SNPs) that influence the maternal innate immune response are…”
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Intrapartum Magnesium Sulfate and the Potential for Cardiopulmonary Drug―Drug Interactions by CAMPBELL, Sarah C, STOCKMANN, Chris, BALCH, Alfred, CLARK, Erin A. S, KAMYAR, Manijeh, VARNER, Michael, KORGENSKI, E. Kent, BONKOWSKY, Joshua L, SPIGARELLI, Michael G, SHERWIN, Catherine M. T

“…This study sought to determine the frequency of possible cardiopulmonary drug-drug interactions among pregnant women who received intrapartum magnesium sulfate…”
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Prevention of Recurrent Preterm Birth: Role of the Neonatal Follow-up Program by Clark, Erin A. S., Esplin, Sean, Torres, Leah, Turok, David, Yoder, Bradley A., Varner, Michael W., Winter, Sarah

“…Preterm birth (PTB) is a public health crisis in need of effective preventative strategies. Multi-disciplinary Neonatal Follow-up Programs (NFPs) provide…”
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Team Training/Simulation by CLARK, ERIN A. S, FISHER, JANET, ARAFEH, JULIA, DRUZIN, MAURICE

“…Obstetrical emergencies require the rapid formation of a team with clear communication, strong leadership, and appropriate decision-making to ensure a positive…”
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TAAR1 and 5-HT1B receptor agonists attenuate autism-like irritability and aggression in rats prenatally exposed to valproic acid by Wang, Lien, Clark, Erin A., Hanratty, Lynsey, Koblan, Kenneth S., Foley, Andrew, Dedic, Nina, Bristow, Linda J.

“…Despite the rising prevalence of autism spectrum disorder (ASD), there remains a significant unmet need for pharmacotherapies addressing its core and…”
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Long-term maternal morbidity associated with repeat cesarean delivery by Clark, Erin A.S., MD, Silver, Robert M., MD

“…Concern regarding the association between cesarean delivery and long-term maternal morbidity is growing as the rate of cesarean delivery continues to increase…”
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Pregnancy-Associated Death in Utah: Contribution of Drug-Induced Deaths by Smid, Marcela C., Stone, Nicole M., Baksh, Laurie, Debbink, Michelle P., Einerson, Brett D., Varner, Michael W., Gordon, Adam J., Clark, Erin A. S.

“…OBJECTIVE:Drug-induced deaths, defined as intentional or unintentional consumption of illicit substances or diverted medications leading to death, are the…”
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Risk Factors, Etiologies, and Screening Tools for Sepsis in Pregnant Women: A Multicenter Case–Control Study by Bauer, Melissa E., Housey, Michelle, Bauer, Samuel T., Behrmann, Sydney, Chau, Anthony, Clancy, Caitlin, Clark, Erin A. S., Einav, Sharon, Langen, Elizabeth, Leffert, Lisa, Lin, Stephanie, Madapu, Manokanth, Maile, Michael D., McQuaid-Hanson, Emily, Priessnitz, Kristina, Sela, Hen Y., Shah, Anuj, Sobolewski, Paul, Toledo, Paloma, Tsen, Lawrence C., Bateman, Brian T.

“…BACKGROUND:Given the significant morbidity and mortality of maternal sepsis, early identification is key to improve outcomes. This study aims to evaluate the…”
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