Search Results - "Clark, Benjamin A"
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Evaluation of DNA Vaccine Candidates against Foot-and-Mouth Disease Virus in Cattle
Published in Vaccines (Basel) (01-02-2023)“…We evaluated four DNA vaccine candidates for their ability to produce virus-like particles (VLPs) and elicit a protective immune response against…”
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Effect of Foot-and-Mouth Disease Virus 2B Viroporin on Expression and Extraction of Mammalian Cell Culture Produced Foot-and-Mouth Disease Virus-like Particles
Published in Vaccines (Basel) (01-09-2022)“…To improve the production of foot-and-mouth disease (FMD) molecular vaccines, we sought to understand the effects of the FMD virus (FMDV) 2B viroporin in an…”
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The L83L ORF of African swine fever virus strain Georgia encodes for a non-essential gene that interacts with the host protein IL-1β
Published in Virus research (02-04-2018)“…•L83L is an early expressed protein in ASFV.•L83L is a binding partner for host protein Il-1β.•Deletion of L83L in ASFV does not decrease virus virulence in…”
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Foot-and-Mouth Disease (FMD) Virus 3C Protease Mutant L127P: Implications for FMD Vaccine Development
Published in Journal of virology (15-11-2017)“…The foot-and-mouth disease virus (FMDV) afflicts livestock in more than 80 countries, limiting food production and global trade. Production of foot-and-mouth…”
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Effect of foot-and-mouth disease virus 3C protease B2 β-strand proline mutagenesis on expression and processing of the P1 polypeptide using a plasmid expression vector
Published in Journal of general virology (01-03-2019)“…The production of experimental molecular vaccines against foot-and-mouth disease virus utilizes the viral encoded 3C protease for processing of the P1…”
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Production of foot-and-mouth disease virus capsid proteins by the TEV protease
Published in Journal of biotechnology (10-06-2018)“…•Use of FMDV 2A sequence to produce TEVpro and substrate from a single ORF.•TEVpro processes a modified FMDV P1 polypeptide to produce FMDV capsid…”
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Evaluation of modified Vaccinia Ankara-based vaccines against foot-and-mouth disease serotype A24 in cattle
Published in Vaccine (22-01-2020)“…•FMDV P1 and 3C expression levels optimized for vaccine production in CEF cells.•Correct FMDV P1 antigen expression and processing in bovine cells.•MVA-BN-FMD…”
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Validation of a site-specific recombination cloning technique for the rapid development of a full-length cDNA clone of a virulent field strain of vesicular stomatitis New Jersey virus
Published in Journal of virological methods (01-03-2019)“…•A full-length clone system to produce infectious VSV was constructed by site-specific recombination.•The virulence of rescued VSV was evaluated in…”
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Effect of Foot-and-Mouth Disease Virus 2B Viroporin on Expression and Extraction of Mammalian Cell Culture Produced Foot-and-Mouth Disease Virus-like Particles
Published in Vaccines (Basel) (01-09-2022)“…To improve the production of foot-and-mouth disease (FMD) molecular vaccines, we sought to understand the effects of the FMD virus (FMDV) 2B viroporin in an…”
Get full text
Journal Article