Search Results - "Clarence W. Chan"

Crystal structures of an unmodified bacterial tRNA reveal intrinsic structural flexibility and plasticity as general properties of unbound tRNAs by Chan, Clarence W, Badong, Deanna, Rajan, Rakhi, Mondragón, Alfonso

“…Ubiquitous across all domains of life, tRNAs constitute an essential component of cellular physiology, carry out an indispensable role in protein synthesis,…”
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Longitudinal SARS-CoV-2 antibody study using the Easy Check COVID-19 IgM/IgG™ lateral flow assay by Higgins, Renee L, Rawlings, Stephen A, Case, Jamie, Lee, Florence Y, Chan, Clarence W, Barrick, Bethany, Burger, Zoe C, Yeo, Kiang-Teck J, Marrinucci, Dena

“…Since the initial identification of the novel coronavirus SARS-CoV-2 in December of 2019, researchers have raced to understand its pathogenesis and begun…”
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Is Adding IgM Antibody to Polymerase Chain Reaction Testing Useful for COVID-19 Travel Screening? by Yi, Xin, Chan, Clarence W, Yeo, Kiang-Teck J

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Structural insights into the assembly of the histone deacetylase-associated Sin3L/Rpd3L corepressor complex by Clark, Michael D, Ryan Marcum, Richard Graveline, Clarence W. Chan, Tao Xie, Zhonglei Chen, Yujia Ding, Yongbo Zhang, Alfonso Mondragón, Gregory David, Ishwar Radhakrishnan

“…Acetylation is correlated with chromatin decondensation and transcriptional activation, but its regulation by histone deacetylase (HDAC)-bearing corepressor…”
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Crystal structure of an atypical cobalamin riboswitch reveals RNA structural adaptability as basis for promiscuous ligand binding by Chan, Clarence W, Mondragón, Alfonso

“…Abstract Cobalamin riboswitches encompass a structurally diverse group of cis-acting, gene regulatory elements found mostly in bacterial messenger RNA and are…”
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Virtual Pathology Elective Provides Uninterrupted Medical Education and Impactful Pathology Education During the COVID-19 Pandemic by Fu, Lucy, Swete, Michael, Selgrade, Daniel, Chan, Clarence W., Rodriguez, Raven, Wolniak, Kristy, Blanco, Luis Z.

“…As students do not qualify as essential health care workers, medical education faced severe disruptions during the COVID-19 pandemic including initial…”
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Deep Learning-Based Kinetic Analysis in Paper-Based Analytical Cartridges Integrated with Field-Effect Transistors by Jang, Hyun-June, Joung, Hyou-Arm, Goncharov, Artem, Kanegusuku, Anastasia Gant, Chan, Clarence W., Yeo, Kiang-Teck Jerry, Zhuang, Wen, Ozcan, Aydogan, Chen, Junhong

“…This study explores the fusion of a field-effect transistor (FET), a paper-based analytical cartridge, and the computational power of deep learning (DL) for…”
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Implementation of a Sample Pooling Strategy for the Direct Detection of SARS-CoV-2 by Real-Time Polymerase Chain Reaction During the COVID-19 Pandemic: An Institutional Experience by Chan, Clarence W, Kwon, Seunghyug, Matushek, Scott M, Ciaglia, Carol, Bethel, Cindy, Beavis, Kathleen G

“…Objectives: To report our institutional experience in devising and implementing a pooling protocol and process for severe acute respiratory syndrome…”
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Implementation of a Sample Pooling Strategy for the Direct Detection of SARS-CoV-2 by Real-Time Polymerase Chain Reaction During the COVID-19 Pandemic by Chan, Clarence W, Kwon, Seunghyug, Matushek, Scott M, Ciaglia, Carol, Bethel, Cindy, Beavis, Kathleen G

“…Abstract Objectives To report our institutional experience in devising and implementing a pooling protocol and process for severe acute respiratory syndrome…”
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Crystal Structure of Human Rpp20/Rpp25 Reveals Quaternary Level Adaptation of the Alba Scaffold as Structural Basis for Single-stranded RNA Binding by Chan, Clarence W., Kiesel, Benjamin R., Mondragón, Alfonso

“…Ribonuclease P (RNase P) catalyzes the removal of 5′ leaders of tRNA precursors and its central catalytic RNA subunit is highly conserved across all domains of…”
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Refractory vaccine‐induced immune thrombotic thrombocytopenia (VITT) managed with delayed therapeutic plasma exchange (TPE) by Major, Ajay, Carll, Timothy, Chan, Clarence W., Christenson, Chancey, Aldarweesh, Fatima, Wool, Geoffrey D., Cohen, Kenneth S.

“…Vaccine‐induced immune thrombotic thrombocytopenia (VITT) is a newly described hematologic disorder, which presents as acute thrombocytopenia and thrombosis…”
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Analytical and Clinical Evaluation of the Automated Elecsys Anti–SARS-CoV-2 Antibody Assay on the Roche cobas e602 Analyzer by Chan, Clarence W, Parker, Kyle, Tesic, Vera, Baldwin, Angel, Tang, Nga Yeung, van Wijk, Xander M R, Yeo, Kiang-Teck J

“…Abstract Objectives To evaluate the analytical and clinical performance of the automated Elecsys anti–severe acute respiratory syndrome coronavirus 2…”
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Analytical and Clinical Evaluation of the Semiquantitative Elecsys Anti–SARS-CoV-2 Spike Protein Receptor Binding Domain Antibody Assay on the Roche cobas e602 Analyzer by Chan, Clarence W, Yi, Xin, Lenza, Michael, Baldwin, Angel D, Jakalski, Jennifer, Tesic, Vera, Yeo, Kiang-Teck J

“…Abstract Objectives To analytically and clinically evaluate the semiquantitative Elecsys anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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Persistence of Ad26.COV2.S‐associated vaccine‐induced immune thrombotic thrombocytopenia (VITT) and specific detection of VITT antibodies by Kanack, Adam J., Singh, Bandana, George, Gemlyn, Gundabolu, Krishna, Koepsell, Scott A., Abou‐Ismail, Mouhamed Yazan, Moser, Karen A., Smock, Kristi J., Green, David, Major, Ajay, Chan, Clarence W., Wool, Geoffrey D., Reding, Mark, Ashrani, Aneel A., Bayas, Antonios, Grill, Diane E., Padmanabhan, Anand

“…Rare cases of COVID‐19 vaccinated individuals develop anti‐platelet factor 4 (PF4) antibodies that cause thrombocytopenia and thrombotic complications, a…”
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Evaluation of the Truvian Easy Check COVID-19 IgM/IgG Lateral Flow Device for Rapid Anti-SARS-CoV-2 Antibody Detection by Chan, Clarence W, Shahul, Sajid, Coleman, Cheyenne, Tesic, Vera, Parker, Kyle, Yeo, Kiang-Teck J

“…Abstract Objectives To evaluate the analytical and clinical performance of the Truvian Easy Check coronavirus disease 2019 (COVID-19) IgM/IgG anti-severe acute…”
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Emerging structural themes in large RNA molecules by Reiter, Nicholas J, Chan, Clarence W, Mondragón, Alfonso

“…► Analysis of recent structures of large RNA molecules shows that they have organized domain architectures. ► The structures are stabilized by a wide range of…”
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Structure and function of the T-loop structural motif in noncoding RNAs by Chan, Clarence W., Chetnani, Bhaskar, Mondragón, Alfonso

“…The T‐loop is a frequently occurring five‐nucleotide motif found in the structure of noncoding RNAs where it is commonly assumed to play an important role in…”
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Use of a Vanadate Oxidation Conjugated Bilirubin Assay to Reduce Test Cancellations Resulting from Hemolyzed Specimens in Pediatric Patients by Kaumeyer, Benjamin A, Tjota, Melissa Y, Parker, Kyle, Chan, Clarence W, Gant Kanegusuku, Anastasia, Baldwin, Angel D, Yeo, Kiang-Teck J

“…Abstract Objectives We sought to replace the highly hemolysis-susceptible diazo conjugated bilirubin (Bc) assay with the more robust vanadate oxidation method…”
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Implementation of pharmacogenomics testing for precision medicine by Kanegusuku, Anastasia L Gant, Chan, Clarence W, O'Donnell, Peter H, Yeo, Kiang-Teck J

“…Great strides have been made in the past decade to lower barriers to clinical pharmacogenomics implementation. Nevertheless, PGx consultation prior to…”
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Crystal structures of an unmodified bacterial tRNA reveal intrinsic structural flexibility and plasticity as general propertiesof unbound tRNAs by Chan, Clarence W., Badong, Deanna, Rajan, Rakhi, Mondragón, Alfonso

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