JPred: a consensus secondary structure prediction server

JPred: a consensus secondary structure prediction server

An interactive protein secondary structure prediction Internet server is presented. The server allows a single sequence or multiple alignment to be submitted, and returns predictions from six secondary structure prediction algorithms that exploit evolutionary information from multiple sequences. A c...

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Bibliographic Details
Published in:Bioinformatics (Oxford, England) Vol. 14; no. 10; pp. 892 - 893
Main Authors: Cuff, J.A, Clamp, M.E, Siddiqui, A.S, Finlay, M, Barton, G.J
Format: Journal Article
Language:English
Published: Oxford Oxford University Press 1998
Subjects:
Algorithms
amino acid sequences
Biological and medical sciences
chemical structure
Computational Biology
Consensus Sequence
Fundamental and applied biological sciences. Psychology
General aspects
Internet
Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)
prediction
Protein Structure, Secondary
proteins
Sequence Alignment
Software
Investigation method
Computerized processing
Prediction
Web site
Secondary structure
Protein
Structural analysis
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Description
Summary:An interactive protein secondary structure prediction Internet server is presented. The server allows a single sequence or multiple alignment to be submitted, and returns predictions from six secondary structure prediction algorithms that exploit evolutionary information from multiple sequences. A consensus prediction is also returned which improves the average Q3 accuracy of prediction by 1% to 72.9%. The server simplifies the use of current prediction algorithms and allows conservation patterns important to structure and function to be identified. http://barton.ebi.ac.uk/servers/jpred.h tml geoff@ebi.ac.uk
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ISSN:1367-4803
1367-4811
DOI:10.1093/bioinformatics/14.10.892