Search Results - "Claeys, Kimberly"
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Imipenem‐Cilastatin‐Relebactam: A Novel β‐Lactam–β‐Lactamase Inhibitor Combination for the Treatment of Multidrug‐Resistant Gram‐Negative Infections
Published in Pharmacotherapy (01-04-2020)“…Imipenem‐cilastatin‐relebactam (IMI‐REL) is a novel β‐lactam–β‐lactamase inhibitor combination recently approved for the treatment of complicated urinary tract…”
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The Diagnosis and Treatment of Adult Urinary Tract Infections in the Emergency Department
Published in Emergency medicine clinics of North America (01-05-2024)“…Emergency medicine has been called the art of “making complicated clinical decisions with limited information.” This description is particularly relevant in…”
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Behavioral Strategies in Diagnostic Stewardship
Published in Infectious disease clinics of North America (01-12-2023)“…Diagnostic stewardship refers to the responsible and judicious use of diagnostic tests to reduce low value care and improve patient outcomes. This article…”
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Time Is of the Essence: The Impact of Delayed Antibiotic Therapy on Patient Outcomes in Hospital-Onset Enterococcal Bloodstream Infections
Published in Clinical infectious diseases (15-05-2016)“…Background. With increasing prevalence of vancomycin-resistant enterococci (VRE), appropriate antibiotic therapy for enterococcal bloodstream infections (EBSI)…”
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The Battle Is on: New Beta-Lactams for the Treatment of Multidrug-Resistant Gram-Negative Organisms
Published in Current infectious disease reports (13-01-2020)“…Purpose of Review Resistant gram-negative infections are becoming increasingly difficult to treat, prompting increased focus on drug development. This review…”
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Leveraging diagnostic stewardship within antimicrobial stewardship programmes
Published in Drugs in Context (20-02-2023)“…Novel diagnostic stewardship in infectious disease consists of interventions that modify ordering, processing, and reporting of diagnostic tests to provide the…”
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Day at the Races: Comparing BioFire FilmArray Blood Culture ID Panels With Verigene Blood Culture Panel in Gram-Negative Bloodstream Infections Using DOOR-MAT Analysis
Published in Clinical infectious diseases (15-09-2021)“…Abstract Three rapid diagnostic test panels (Verigene BC-GN, BioFire BCID, and BCID 2 [RUO]) were compared using the Desirability of Outcome Ranking Management…”
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Implementing diagnostic stewardship to improve diagnosis of urinary tract infections across three medical centers: A qualitative assessment
Published in Infection control and hospital epidemiology (01-12-2023)“…Urine-culture diagnostic stewardship aims to decrease misdiagnosis of urinary tract infections (UTIs); however, these interventions are not widely adopted. We…”
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Making the change to area under the curve–based vancomycin dosing
Published in American journal of health-system pharmacy (15-12-2018)Get full text
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Optimal Urine Culture Diagnostic Stewardship Practice—Results from an Expert Modified-Delphi Procedure
Published in Clinical infectious diseases (31-08-2022)“…Abstract Background Urine cultures are nonspecific and often lead to misdiagnosis of urinary tract infection and unnecessary antibiotics. Diagnostic…”
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Diagnostic and antimicrobial stewardship with molecular respiratory testing across the SHEA Research Network
Published in Infection control and hospital epidemiology (01-08-2021)“…This survey investigated diagnostic and antimicrobial stewardship practices related to molecular respiratory panel testing in adults with lower respiratory…”
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Does calculation method matter for targeting vancomycin area under the curve?
Published in Journal of antimicrobial chemotherapy (28-07-2022)“…Abstract Objectives To assess differences in vancomycin AUC estimates from two common, clinically applied first-order pharmacokinetic equation methods compared…”
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Comparing the Clinical Utility of Rapid Diagnostics for Treatment of Bloodstream Infections Using Desirability of Outcome Ranking Approach for the Management of Antibiotic Therapy (DOOR-MAT)
Published in Antimicrobial agents and chemotherapy (17-08-2021)“…Decisions regarding which rapid diagnostic test (RDT) for bloodstream infections to implement remain challenging given the diversity of organisms detected by…”
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An Antibiotic Stewardship Program Blueprint for Optimizing Verigene BC-GN within an Institution: a Tale of Two Cities
Published in Antimicrobial agents and chemotherapy (01-05-2018)“…Rapid diagnostic tests (RDTs) have revolutionized the management of Gram-negative bacteremia by allowing antimicrobial stewardship teams the ability to…”
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Diagnostic stewardship: what impacts antibiotics use?
Published in Current opinion in infectious diseases (01-08-2023)“…The aim of this study was to review recently published diagnostic stewardship studies of common clinical infectious syndromes and the impact on antibiotic…”
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Association between vancomycin day 1 exposure profile and outcomes among patients with methicillin-resistant Staphylococcus aureus infective endocarditis
Published in Antimicrobial agents and chemotherapy (01-06-2015)“…Given the critical importance of early appropriate therapy, a retrospective cohort (2002 to 2013) was performed at the Detroit Medical Center to evaluate the…”
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Advances and Challenges in the Diagnosis and Treatment of Urinary Tract Infections: the Need for Diagnostic Stewardship
Published in Current infectious disease reports (01-04-2019)“…Purpose of Review Urinary tract infections (UTIs), including catheter-associated UTIs, are among the most common bacterial infections in both inpatient and…”
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No Crystal Ball? Using Risk Factors and Scoring Systems to Predict Extended-Spectrum Beta-Lactamase Producing Enterobacterales (ESBL-E) and Carbapenem-Resistant Enterobacterales (CRE) Infections
Published in Current infectious disease reports (01-11-2022)“…Purpose of Review Predicting whether a hospitalized patient is infected with an ESBL-E or CRE remains challenging and often leads to overutilization of…”
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Multicenter Observational Study of Ceftaroline Fosamil for Methicillin-Resistant Staphylococcus aureus Bloodstream Infections
Published in Antimicrobial agents and chemotherapy (01-02-2017)“…Novel therapies for methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI) are needed in the setting of reduced antibiotic…”
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From bottle to bedside: Implementation considerations and antimicrobial stewardship considerations for bloodstream infection rapid diagnostic testing
Published in Pharmacotherapy (01-08-2023)“…Antimicrobial stewardship (AMS) programs have been quick to adopt novel molecular rapid diagnostic technologies (mRDTs) for bloodstream infections (BSIs) to…”
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