Search Results - "Claasen, J"
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Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies
Published in Blood (17-11-2022)“…•Venetoclax resistance is mediated by methylation and silencing of PUMA.•Treatment algorithms should consider the PUMA, MCL1, and BAX status. [Display omitted]…”
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Prognostic relevance of topoisomerase II α and minichromosome maintenance protein 6 expression in colorectal cancer
Published in BMC cancer (09-05-2019)“…Despite rising incidence rates of colorectal malignancies, only a few prognostic tools have been implemented in proven clinical routine. Cell division and…”
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20 Dwelling Large-Scale Experiment of Fire Spread in Informal Settlements
Published in Fire technology (01-07-2020)“…Large-scale urban conflagrations in informal settlements are a frequent global event, however there is a lack of experimental research and knowledge within…”
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Prognostic relevance of topoisomerase II [alpha] and minichromosome maintenance protein 6 expression in colorectal cancer
Published in BMC cancer (09-05-2019)“…Background Despite rising incidence rates of colorectal malignancies, only a few prognostic tools have been implemented in proven clinical routine. Cell…”
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Involvement of benzodiazepine receptors in neuroinflammatory and neurodegenerative diseases: evidence from activated microglial cells in vitro
Published in Neurobiology of disease (01-12-2003)“…Increased binding of a ligand for the peripheral benzodiazepine binding receptor is currently used in PET studies as an in vivo measurement of inflammation in…”
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Inflammation Is Detrimental for Neurogenesis in Adult Brain
Published in Proceedings of the National Academy of Sciences - PNAS (11-11-2003)“…New hippocampal neurons are continuously generated in the adult brain. Here, we demonstrate that lipopolysaccharide-induced inflammation, which gives rise to…”
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Action of novel CD37 antibodies on chronic lymphocytic leukemia cells
Published in Leukemia (01-03-2012)Get full text
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Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils
Published in International journal of immunopathology and pharmacology (01-10-2009)“…Alpha-Synuclein (alpha-Syn) accounts, as a major component of Lewy bodies (LB), for the filamentous deposits in many cases of neurodegenerative diseases. Yet,…”
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Photorhabdus africana sp. nov. isolated from Heterorhabditis entomopathogenic nematodes
Published in Current microbiology (01-08-2024)“…One Gram-negative, rod-shaped bacterial strain, isolated from an undescribed Heterorhabditis entomopathogenic nematode species was characterized to determine…”
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TNF-α antibody infusion impairs survival of stroke-generated neuroblasts in adult rat brain
Published in Experimental neurology (01-11-2005)“…Stroke induced by 2 h middle cerebral artery occlusion triggers increased striatal and hippocampal neurogenesis in adult rats. We investigated the effect of…”
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DIE OPTIMISERING VAN WGISTIEKE STEUN
Published in South African journal of industrial engineering (15-01-2012)“…ENGLISH ABSTRACT: The relationship between system performance and the level of logistic support that a system receives is discussed. A theoretical optimum…”
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TIlE MALCOLM BALDRIDGE NATIONAL QUALITY AWARDS
Published in South African journal of industrial engineering (15-01-2012)“…ENGLISH ABSTRACT: To manage problems , is to try and cope with a flux of interacting events and ideas which unrolls through time - with the manager trying to…”
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A progress report on ultra-high-pressure waterjet cutting underground: the future of narrow reef gold and PGE mining
Published in Journal of the Southern African Institute of Mining and Metallurgy (01-06-2013)“…High-pressure waterjet technology is proposed as an alternative tool for selective underground mining of high-grade ore sections in stratiform orebodies…”
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BETROUBAARHElDS-, BESKlKBAARHElDS- EN LOGlSTlEKE STEUNANALlSE
Published in South African journal of industrial engineering (15-01-2012)“…ENGLISH ABSTRACT: AMIR and SPAR are Monte Carlo based computer software for the reliability, availability and logistic support analysis of complex systems…”
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Environmental and social impact considerations for sustainable project life cycle management in the process industry
Published in Corporate social-responsibility and environmental management (01-03-2005)“…Project management, as a recognized core business competency, must incorporate planning, execution and implementation procedures within a broader…”
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A sequential insertion heuristic for the initial solution to a constrained vehicle routing problem
Published in Orion (Johannesburg, South Africa) (01-06-2006)“…The Vehicle Routing Problem (VRP) is a well-researched problem in the Operations Research literature. It is the view of the authors of this paper that the…”
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Consensus Paper: Management of Degenerative Cerebellar Disorders
Published in Cerebellum (London, England) (01-04-2014)“…Treatment of motor symptoms of degenerative cerebellar ataxia remains difficult. Yet there are recent developments that are likely to lead to significant…”
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The efficacy of two bupivacaine hydrochloride injection products
Published in South African medical journal (01-06-1996)“…The relative efficacy of two bupivacaine hydrochloride injection products was investigated in patients who were undergoing intra-ocular eye surgery. Patients…”
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