Search Results - "Clézardin, P."

Adjuvant bisphosphonates in early breast cancer: consensus guidance for clinical practice from a European Panel by Hadji, P., Coleman, R.E., Wilson, C., Powles, T.J., Clézardin, P., Aapro, M., Costa, L., Body, J.-J., Markopoulos, C., Santini, D., Diel, I., Di Leo, A., Cameron, D., Dodwell, D., Smith, I., Gnant, M., Gray, R., Harbeck, N., Thurlimann, B., Untch, M., Cortes, J., Martin, M., Albert, U.-S., Conte, P.-F., Ejlertsen, B., Bergh, J., Kaufmann, M., Holen, I.

“…Bisphosphonates have been studied in randomised trials in early breast cancer to investigate their ability to prevent cancer treatment-induced bone loss…”
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Peroxiredoxin 2 specifically regulates the oxidative and metabolic stress response of human metastatic breast cancer cells in lungs by Stresing, V, Baltziskueta, E, Rubio, N, Blanco, J, Arriba, MaC, Valls, J, Janier, M, Clézardin, P, Sanz-Pamplona, R, Nieva, C, Marro, M, Dmitri, P, Sierra, A

“…Little is known about metastatic pathways that are specific to the lung rather than other organs. We previously showed that antioxidant proteins such as…”
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The RANK–RANKL axis: an opportunity for drug repurposing in cancer? by Peters, S., Clézardin, P., Márquez-Rodas, I., Niepel, D., Gedye, C.

“…Drug repurposing offers advantages over traditional drug development in terms of cost, speed and improved patient outcomes. The receptor activator of nuclear…”
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Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo by Gibert, B, Eckel, B, Gonin, V, Goldschneider, D, Fombonne, J, Deux, B, Mehlen, P, Arrigo, A-P, Clézardin, P, Diaz-Latoud, C

“…Background: The small stress heat shock protein 27 (Hsp27) has recently turned as a promising target for cancer treatment. Hsp27 upregulation is associated…”
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Increased Dickkopf-1 expression in breast cancer bone metastases by Voorzanger-Rousselot, N, Goehrig, D, Journe, F, Doriath, V, Body, J J, Clézardin, P, Garnero, P

“…The aim of this study was to determine whether Dickkopf-1 (Dkk-1) expression in breast cancer was associated with bone metastases. We first analysed Dkk-1…”
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ERRα promotes breast cancer cell dissemination to bone by increasing RANK expression in primary breast tumors by Vargas, G., Bouchet, M., Bouazza, L., Reboul, P., Boyault, C., Gervais, M., Kan, C., Benetollo, C., Brevet, M., Croset, M., Mazel, M., Cayrefourcq, L., Geraci, S., Vacher, S., Pantano, F., Filipits, M., Driouch, K., Bieche, I., Gnant, M., Jacot, W., Aubin, J. E., Duterque-Coquillaud, M., Alix-Panabières, C., Clézardin, P., Bonnelye, E.

“…Bone is the most common metastatic site for breast cancer. Estrogen-related-receptor alpha (ERRα) has been implicated in cancer cell invasiveness. Here, we…”
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RANK expression predicts long term outcome in early luminal breast cancer by Kassem, L., Clézardin, P., Treilleux, I.

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Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma by Massy, E, Rousseau, JC, Gueye, M., Bonnelye, E., Brevet, M., Chambard, L., Duruisseaux, M., Borel, O., Roger, C., Guelminger, R., Pialat, J.B., Gineyts, E., Bouazza, L., Millet, M., Maury, JM, Clézardin, P., Girard, N., Confavreux, Cyrille B.

“…•Matrix protein periostin is involved in cancer cell dissemination and bone response.•Serum periostin level was higher in adenocarcinoma lung cancer patients…”
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Influence of human cancer cell lines on mechanical properties of mice tibia by Gardegaront, M., Plet, G., Delpuech, B., Bouazza, L., Brevet, M., Pialat, J.-B., Clézardin, P., Confavreux, C. B., Mitton, D., Follet, H.

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The C-Terminal Intact Forms of Periostin (iPTN) Are Surrogate Markers for Osteolytic Lesions in Experimental Breast Cancer Bone Metastasis by Gineyts, Evelyne, Bonnet, Nicolas, Bertholon, Cindy, Millet, Marjorie, Pagnon-Minot, Aurélie, Borel, Olivier, Geraci, Sandra, Bonnelye, Edith, Croset, Martine, Suhail, Ali, Truica, Cristina, Lamparella, Nicholas, Leitzel, Kim, Hartmann, Daniel, Chapurlat, Roland, Lipton, Allan, Garnero, Patrick, Ferrari, Serge, Clézardin, Philippe, Rousseau, Jean-Charles

“…Periostin is an extracellular matrix protein that actively contributes to tumor progression and metastasis. Here, we hypothesized that it could be a marker of…”
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Early Detection of Bone Metastases in a Murine Model Using Fluorescent Human Breast Cancer Cells: Application to the Use of the Bisphosphonate Zoledronic Acid in the Treatment of Osteolytic Lesions by Peyruchaud, Olivier, Winding, Bent, Pécheur, Isabelle, Serre, Claire‐Marie, Delmas, Pierre, Clézardin, Philippe

“…A very common metastatic site for human breast cancer is bone. The traditional bone metastasis model requires human MDA‐MB‐231 breast carcinoma cell…”
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Upregulation of the mevalonate pathway by cholesterol depletion abolishes tolerance to N-bisphosphonate induced Vγ9Vδ2 T cell cytotoxicity in PC-3 prostate cancer cells by Arkko, S, Zlatev, H.P, Mönkkönen, H, Räikkönen, J, Benzaïd, I, Clézardin, P, Mönkkönen, J, Määttä, J.A

“…Highlights • PC-3 prostate cancer cells treated with zoledronate were shown to be resistant to Vγ9Vδ2 T cell cytotoxicity. • Resistance was attributed to the…”
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The role of the calcium sensing receptor in the migration of breast cancer cells by Thiem, U, Boudot, C, Lopez, I, Hénaut, L, Clézardin, P, Kamel, S, Mentaverri, R

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Effect of lysophosphatidic acid (LPA) on osteoclastogenesis by Serre, C.M, Ribeiro, J, Bonnelye, E, Clézardin, P, Peyruchaud, O

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Erratum to “Periostin as a circulating marker for breast cancer bone metastases” [Bone 47S2 (2010) S328–S329] by Contié, S, Voorzanger-Rousselot, N, Litvin, J, Clézardin, P, Garnero, P

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Integrins in bone metastasis formation and potential therapeutic implications by Clëzardin, P

“…Integrins constitute a family of cell surface receptors that are heterodimers composed of noncovalently associated alpha and beta subunits. Integrins bind to…”
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Twist 1 expression in an osteotropic breast cancer cell line promotes bone metastasis formation in mouse by Croset, M, Goëhrig, D, Bonnelye, E, Ansieau, S, Puisieux, A, Clézardin, P

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Zoledronic acid induces IPP accumulation and release from human cancer cells, which activates Vγ9Vδ2 T cell-differentiation and migration in vitro and mediates Vγ9Vδ2 T cell-induced cancer cell death in vivo by Benzaid, I, Monkkonen, H, Stresing, V, Bonnelye, E, Green, J, Monkkonen, J, Clézardin, P

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Interaction of autotaxin with breast cancer cell integrins might contribute to lysophosphatidic acid-mediated bone metastases by David, M, Leblanc, R, Deux, B, Serre, C.M, Ribeiro, J, Clézardin, P, Peyruchaud, O

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Propriétés antitumorales du bisphosphonate zolédronate et implications thérapeutiques potentielles en clinique by CLEZARDIN, P

“…Le zolédronate ainsi que les autres bisphosphonates inhibent la résorption osseuse en bloquant l'activité des ostéoclastes. C'est pour cette raison qu'ils sont…”
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