Search Results - "Ciura Krzesimir"

Stabilization and isotachophoresis of unmodified gold nanoparticles in capillary electrophoresis by Dziomba, Szymon, Ciura, Krzesimir, Correia, Bruna, Wielgomas, Bartosz

“…Capillary zone electrophoresis (CZE) of gold nanoparticles (Au NPs) was investigated in terms of dispersion stability during the analysis process. It was shown…”
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Gold nanoparticles dispersion stability under dynamic coating conditions in capillary zone electrophoresis by Dziomba, Szymon, Ciura, Krzesimir, Kocialkowska, Paulina, Prahl, Adam, Wielgomas, Bartosz

“…•CZE of gold nanoparticles (Au NPs) was investigated under dynamic coating conditions.•Factors influencing Au NPs dispersion stability in CZE were…”
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Predicting zeta potential of liposomes from their structure: A nano-QSPR model for DOPE, DC-Chol, DOTAP, and EPC formulations by Jarzynska, Kamila, Gajewicz-Skretna, Agnieszka, Ciura, Krzesimir, Puzyn, Tomasz

“…Liposomes, nanoscale spherical structures composed of amphiphilic lipids, hold great promise for various pharmaceutical applications, especially as…”
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Capillary zone electrophoresis of bacterial extracellular vesicles: A proof of concept by Piotrowska, Martyna, Ciura, Krzesimir, Zalewska, Michalina, Dawid, Marta, Correia, Bruna, Sawicka, Paulina, Lewczuk, Bogdan, Kasprzyk, Joanna, Sola, Laura, Piekoszewski, Wojciech, Wielgomas, Bartosz, Waleron, Krzysztof, Dziomba, Szymon

“…•Extracellular vesicles (EVs) from Pectobacterium sp. were characterized for the first time.•Capillary electrophoresis of EVs was presented.•The CE method was…”
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A Novel Approach to Optimize Hot Melt Impregnation in Terms of Amorphization Efficiency by Garbera, Kamil, Ciura, Krzesimir, Sawicki, Wiesław

“…In this study, an innovative methodology to optimize amorphization during the hot melt impregnation (HMI) process was proposed. The novelty of this report…”
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Lipophilicity Determination of Quaternary (Fluoro)Quinolones by Chromatographic and Theoretical Approaches by Ciura, Krzesimir, Fedorowicz, Joanna, Andrić, Filip, Greber, Katarzyna Ewa, Gurgielewicz, Alina, Sawicki, Wiesław, Sączewski, Jarosław

“…Lipophilicity is a vital physicochemical parameter of a molecule, which affects several biological processes such as absorption, tissue distribution, and…”
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Green synthesis of 1,3,5-triazine derivatives using a sonochemical protocol by Kułaga, Damian, Drabczyk, Anna K., Zaręba, Przemysław, Jaśkowska, Jolanta, Chrzan, Julia, Ewa Greber, Katarzyna, Ciura, Krzesimir, Plażuk, Damian, Wielgus, Ewelina

“…[Display omitted] •Triazine derivatives can be obtained with more than 70% of yield within 5 mins.•Sonochemical approach requires water as…”
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Menthol- and thymol-based ciprofloxacin derivatives against Mycobacterium tuberculosis: in vitro activity, lipophilicity, and computational studies by Szulczyk, Daniel, Woziński, Mateusz, Koliński, Michał, Kmiecik, Sebastian, Głogowska, Agnieszka, Augustynowicz-Kopeć, Ewa, Dobrowolski, Michał A., Roszkowski, Piotr, Struga, Marta, Ciura, Krzesimir

“…In this work, we investigated the antitubercular properties of Ciprofloxacin derivatives conjugated with menthol and thymol moieties. For the sixteen…”
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Evaluation of Physicochemical Properties of Ipsapirone Derivatives Based on Chromatographic and Chemometric Approaches by Nisterenko, Wiktor, Kułaga, Damian, Woziński, Mateusz, Singh, Yash Raj, Judzińska, Beata, Jagiello, Karolina, Greber, Katarzyna Ewa, Sawicki, Wiesław, Ciura, Krzesimir

“…Drug discovery is a challenging process, with many compounds failing to progress due to unmet pharmacokinetic criteria. Lipophilicity is an important…”
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Low-Basicity 5-HT6 Receptor Ligands from the Group of Cyclic Arylguanidine Derivatives and Their Antiproliferative Activity Evaluation by Zaręba, Przemysław, Drabczyk, Anna K., Wnorowski, Artur, Maj, Maciej, Malarz, Katarzyna, Rurka, Patryk, Latacz, Gniewomir, Duszyńska, Beata, Ciura, Krzesimir, Greber, Katarzyna Ewa, Boguszewska-Czubara, Anna, Śliwa, Paweł, Kuliś, Julia

“…The serotonin 5-HT6 receptor (5-HT6R), expressed almost exclusively in the brain, affects the Cdk5 signaling as well as the mTOR pathway. Due to the…”
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Modeling of Anticancer Sulfonamide Derivatives Lipophilicity by Chemometric and Quantitative Structure-Retention Relationships Approaches by Pastewska, Monika, Żołnowska, Beata, Kovačević, Strahinja, Kapica, Hanna, Gromelski, Maciej, Stoliński, Filip, Sławiński, Jarosław, Sawicki, Wiesław, Ciura, Krzesimir

“…Sulfonamides are a classic group of chemotherapeutic drugs with a broad spectrum of pharmacological action, including anticancer activity. In this work,…”
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Development of Safirinium dyes for new applications: fluorescent staining of bacteria, human kidney cells, and the horny layer of the epidermis by Fedorowicz, Joanna, Bazar, Dagmara, Brankiewicz, Wioletta, Kapica, Hanna, Ciura, Krzesimir, Zalewska-Piątek, Beata, Piątek, Rafał, Cal, Krzysztof, Mojsiewicz-Pieńkowska, Krystyna, Sączewski, Jarosław

“…Low-molecular synthetic fluorophores are convenient tools in bioimaging applications. Several derivatives of Safirinium dyes as well as their reactive N…”
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Affinity of Antifungal Isoxazolo[3,4- b ]pyridine-3(1 H )-Ones to Phospholipids in Immobilized Artificial Membrane (IAM) Chromatography by Ciura, Krzesimir, Fedorowicz, Joanna, Žuvela, Petar, Lovrić, Mario, Kapica, Hanna, Baranowski, Paweł, Sawicki, Wiesław, Wong, Ming Wah, Sączewski, Jarosław

“…Currently, rapid evaluation of the physicochemical parameters of drug candidates, such as lipophilicity, is in high demand owing to it enabling the…”
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Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency by Dernovšek, Jaka, Zajec, Živa, Poje, Goran, Urbančič, Dunja, Sturtzel, Caterina, Goričan, Tjaša, Grissenberger, Sarah, Ciura, Krzesimir, Woziński, Mateusz, Gedgaudas, Marius, Zubrienė, Asta, Grdadolnik, Simona Golič, Mlinarič-Raščan, Irena, Rajić, Zrinka, Cotman, Andrej Emanuel, Zidar, Nace, Distel, Martin, Tomašič, Tihomir

“…The development of new anticancer agents is one of the most urgent topics in drug discovery. Inhibition of molecular chaperone Hsp90 stands out as an approach…”
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The Effects of Two Kinds of Dietary Interventions on Serum Metabolic Profiles in Haemodialysis Patients by Kozlowska, Lucyna, Jagiello, Karolina, Ciura, Krzesimir, Sosnowska, Anita, Zwiech, Rafal, Zbrog, Zbigniew, Wasowicz, Wojciech, Gromadzinska, Jolanta

“…The goal of this study was to evaluate the effects of two kinds of 24-week dietary interventions in haemodialysis patients, a traditional nutritional…”
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Comprehensive Assessment of the Stability of Selected Coxibs in Variable Environmental Conditions along with the Assessment of Their Potential Hepatotoxicity by Gumułka, Paweł, Pecio, Łukasz, Żmudzki, Paweł, Ciura, Krzesimir, Skalicka-Woźniak, Krystyna, Dąbrowska, Monika, Starek, Małgorzata

“…Determining the influence of environmental factors on the stability of drugs is very helpful when choosing excipients, storage conditions or packaging…”
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Modeling of small molecule's affinity to phospholipids using IAM-HPLC and QSRR approach enhanced by similarity-based machine algorithms by Ciura, Krzesimir

“…•First implementation of locally weighted least squares kernel regression for QSRR.•Highly predictive QSRR model of IAM chromatography.•Lipophilicity, charge,…”
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Can Immobilized Artificial Membrane Chromatography Support the Characterization of Antimicrobial Peptide Origin Derivatives? by Ciura, Krzesimir, Ptaszyńska, Natalia, Kapica, Hanna, Pastewska, Monika, Łęgowska, Anna, Rolka, Krzysztof, Kamysz, Wojciech, Sawicki, Wiesław, Greber, Katarzyna E.

“…The emergence and spread of multiple drug-resistant bacteria strains caused the development of new antibiotics to be one of the most important challenges of…”
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Application and Validation of Simple Isocratic HPLC-UV-DAD Method with Dual Wavelength Detection for Ivabradine Determination and Its Application in the Study of Stress Degradation by Ciura, Krzesimir, Marszałł, Marcin, Pikul, Piotr, Nowakowska, Joanna

“…Ivabradine is a modern drug that selectively lowers the heart rate, improves cardiac energy balance, and reduces heart’s demands for oxygen and energy. Due to…”
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A simple TLC and HPTLC method for separation of selected steroid drugs by Nowakowska Joanna, Pikul Piotr, Ciura Krzesimir, Piotrowicz Jakub

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