Search Results - "Citores, Lucía"
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Antiviral Activity of Ribosome-Inactivating Proteins
Published in Toxins (22-01-2021)“…Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2.2.22) that inactivate ribosomes thus inhibiting protein synthesis. The…”
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Ageritin, a Ribotoxin from Poplar Mushroom (Agrocybe aegerita) with Defensive and Antiproliferative Activities
Published in ACS chemical biology (21-06-2019)“…Ribotoxins make up a group of extracellular rRNA endoribonucleases produced by ascomycetes that display cytotoxicity toward animal cells, having been proposed…”
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Biological Activities of Ribosome-Inactivating Proteins
Published in Toxins (01-01-2023)“…After more than 50 years of research, studies on the structure and biological activities of ribosome-inactivating proteins (RIPs) continue to provide a field…”
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The Biological Action and Structural Characterization of Eryngitin 3 and 4, Ribotoxin-like Proteins from Pleurotus eryngii Fruiting Bodies
Published in International journal of molecular sciences (01-10-2023)“…Ribotoxin-like proteins (RL-Ps) are specific ribonucleases found in mushrooms that are able to cleave a single phosphodiester bond located in the sarcin–ricin…”
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Antifungal Activity of Ribosome-Inactivating Proteins
Published in Toxins (01-04-2024)“…The control of crop diseases caused by fungi remains a major problem and there is a need to find effective fungicides that are environmentally friendly. Plants…”
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Sequence comparison and phylogenetic analysis by the Maximum Likelihood method of ribosome-inactivating proteins from angiosperms
Published in Plant molecular biology (01-08-2014)“…Ribosome-inactivating proteins (RIPs) from angiosperms are rRNA N-glycosidases that have been proposed as defence proteins against virus and fungi. They have…”
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Deciphering Molecular Determinants Underlying Penicillium digitatum's Response to Biological and Chemical Antifungal Agents by Tandem Mass Tag (TMT)-Based High-Resolution LC-MS/MS
Published in International journal of molecular sciences (08-01-2022)“…is a widespread pathogen responsible for the postharvest decay of citrus, one of the most economically important crops worldwide. Currently, chemical…”
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Structural and functional characterization of the cytotoxic protein ledodin, an atypical ribosome‐inactivating protein from shiitake mushroom (Lentinula edodes)
Published in Protein science (01-04-2023)“…We have purified ledodin, a cytotoxic 22‐kDa protein from shiitake mushroom (Lentinula edodes) consisting of a 197 amino acid chain. Ledodin possessed…”
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Antifungal Activity of α‑Sarcin against Penicillium digitatum: Proposal of a New Role for Fungal Ribotoxins
Published in ACS chemical biology (17-08-2018)“…Among the putative defense proteins that occur in fungi, one of the best studied is α-sarcin, produced by the mold Aspergillus giganteus. This protein is the…”
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Isolation, Characterization and Biological Action of Type-1 Ribosome-Inactivating Proteins from Tissues of Salsola soda L
Published in Toxins (19-08-2022)“…Ribosome-inactivating proteins (RIPs) are known as RNA N-glycosylases. They depurinate the major rRNA, damaging ribosomes and inhibiting protein synthesis…”
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Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication
Published in Toxins (30-01-2021)“…Ebulin l is an A-B toxin, and despite the presence of a B chain, this toxin displays much less toxicity to cells than the potent A-B toxin ricin. Here, we…”
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Edodin: A New Type of Toxin from Shiitake Mushroom ( Lentinula edodes ) That Inactivates Mammalian Ribosomes
Published in Toxins (01-04-2024)“…Ribosome-inactivating proteins (RIPs) are a group of proteins with rRNA N-glycosylase activity that irreversibly inhibit protein synthesis and consequently…”
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Biological and antipathogenic activities of ribosome-inactivating proteins from Phytolacca dioica L
Published in Biochimica et biophysica acta (01-06-2016)“…The species from the genus Phytolacca constitute one of the best sources of ribosome-inactivating proteins (RIPs) that have been used both in the therapy…”
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Biological activities of the antiviral protein BE27 from sugar beet (Beta vulgaris L.)
Published in Planta (01-02-2015)“…MAIN CONCLUSION : The ribosome inactivating protein BE27 displays several biological activities in vitro that could result in a broad action against several…”
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Sequence, Structure, and Binding Site Analysis of Kirkiin in Comparison with Ricin and Other Type 2 RIPs
Published in Toxins (03-12-2021)“…Kirkiin is a new type 2 ribosome-inactivating protein (RIP) purified from the caudex of with a cytotoxicity compared to that of stenodactylin. The high…”
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Structure and Biological Properties of Ribosome-Inactivating Proteins and Lectins from Elder (Sambucus nigra L.) Leaves
Published in Toxins (01-09-2022)“…Ribosome-inactivating proteins (RIPs) are a group of proteins with rRNA N-glycosylase activity that catalyze the removal of a specific adenine located in the…”
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Primary Sequence and 3D Structure Prediction of the Plant Toxin Stenodactylin
Published in Toxins (21-08-2020)“…Stenodactylin is one of the most potent type 2 ribosome-inactivating proteins (RIPs); its high toxicity has been demonstrated in several models both in vitro…”
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Ebulin-RP, a novel member of the Ebulin gene family with low cytotoxicity as a result of deficient sugar binding domains
Published in Biochimica et biophysica acta. General subjects (01-03-2018)“…Sambucus ebulus is a rich source of ribosome-inactivating proteins (RIPs) and RIP-related lectins generated from multiple genes. These proteins differ in their…”
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Antifungal activity of the ribosome‐inactivating protein BE27 from sugar beet (Beta vulgaris L.) against the green mould Penicillium digitatum
Published in Molecular plant pathology (01-02-2016)“…The ribosome‐inactivating protein BE27 from sugar beet (Beta vulgaris L.) leaves is an apoplastic protein induced by signalling compounds, such as hydrogen…”
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Insight into the phylogenetic relationship and structural features of vertebrate myoglobin family
Published in International journal of biological macromolecules (01-12-2016)“…[Display omitted] •E18, G25, F43, V68, L72, H93 and H97 are present in all jawed vertebrate myoglobins.•E18 interaction with an E-helix residue is conserved in…”
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