Search Results - "Cito, Letizia"
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Novel findings about management of gastric cancer: A summary from 10th IGCC
Published in World journal of gastroenterology (21-07-2014)“…The Tenth International Gastric Cancer Congress(IGCC) was held in Verona, Italy, from June 19 to 22, 2013. The meeting enclosed various aspects of stomach…”
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Journal Article Conference Proceeding -
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CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy
Published in Proceedings of the National Academy of Sciences - PNAS (10-08-2010)“…Tumor growth requires neoangiogenesis. VEGF is the most potent proangiogenic factor. Dysregulation of hypoxia-inducible factor (HIF) or cytokine stimuli such…”
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Journal Article -
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Loss of the tumor suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors
Published in Oncogene (10-03-2005)“…PTEN/MMAC1/TEP1: (hereafter PTEN) is a tumor suppressor gene (located at 10q23) that is frequently mutated or deleted in sporadic human tumors. PTEN encodes a…”
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Dual role of parathyroid hormone in endothelial progenitor cells and marrow stromal mesenchymal stem cells
Published in Journal of cellular physiology (01-02-2010)“…Hematopoietic stem cells derive regulatory information also from parathyroid hormone (PTH). To explore the possibility that PTH may have a role in regulation…”
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Journal Article -
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Overexpression of the S-phase kinase-associated protein 2 in thyroid cancer
Published in Endocrine-related cancer (01-06-2007)“…Loss of expression of the cyclin-dependent kinase inhibitor p27 through enhanced protein degradation frequently occurs in human cancer. Degradation of p27…”
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The Retinoblastoma Family Member pRb2/p130 Is an Independent Predictor of Survival in Human Soft Tissue Sarcomas
Published in Clinical cancer research (01-08-2008)“…Purpose: pRb2/p130, a member of the Retinoblastoma gene family, has been shown to be a powerful prognostic factor in several malignancies. We sought to…”
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Journal Article -
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Critical role of cyclin D3 in TSH-dependent growth of thyrocytes and in hyperproliferative diseases of the thyroid gland
Published in Oncogene (23-10-2003)“…We report that cyclin D3 is rate limiting for G1 progression in thyroid follicular cells and that its constitutive upregulation by chronic stimulation of the…”
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Palliative splenic irradiation in primary and post PV/ET myelofibrosis: outcomes and toxicity of three radiation schedules
Published in Hematology reports (04-05-2009)“…Splenectomy and splenic irradiation (SI) are the sole treatment modalities to control drug resistant splenomegaly in patients with myelofibrosis (MF). SI has…”
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Advances in gastric cancer prevention
Published in World journal of clinical oncology (10-09-2012)“…Gastric cancer is a multifactorial neoplastic pathology numbering among its causes both environmental and genetic predisposing factors. It is mainly diffused…”
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Journal Article -
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Antitumoral potential, antioxidant activity and carotenoid content of two Southern Italy tomato cultivars extracts: San Marzano and Corbarino
Published in Journal of cellular physiology (01-02-2018)“…Gastric cancer represents a diffuse and aggressive neoplasm, whose mortality index is among the highest in the world. Predisposing factors are E‐cadherin…”
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Translational Research and Plasma Proteomic in Cancer
Published in Journal of cellular biochemistry (01-04-2016)“…ABSTRACT Proteomics is a recent field of research in molecular biology that can help in the fight against cancer through the search for biomarkers that can…”
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Journal Article -
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The inhibition of p85αPI3KSer83 phosphorylation prevents cell proliferation and invasion in prostate cancer cells
Published in Journal of cellular biochemistry (01-09-2013)“…Phosphoinositide 3‐kinase proteins are composed by a catalytic p110 subunit and a regulatory p85 subunit. There are three classes of PI3K, named class I–III,…”
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Journal Article -
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pRb2/p130 Localizes to the Cytoplasm in Diffuse Gastric Cancer
Published in Journal of cellular physiology (01-04-2015)“…pRb2/p130 is a key tumor suppressor, whose oncosuppressive activity has mainly been attributed to its ability to negatively regulate cell cycle by interacting…”
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Activation of urokinase receptor by a novel interaction between the connecting peptide region of urokinase and alpha v beta 5 integrin
Published in Journal of cell science (15-08-2006)“…The serine protease urokinase (uPA) binds to the urokinase receptor (uPAR) through its growth-factor domain (GFD, residues 1-49), affecting cell migration,…”
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Rb family proteins in gastric cancer (Review)
Published in Oncology reports (01-12-2010)“…Gastric cancer is one of the most diffuse neoplastic pathologies in the world whose environmental and molecular causes, although deeply investigated, have not…”
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Journal Article -
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Activation of urokinase receptor by a novel interaction between the connecting peptide region of urokinase and αvβ5 integrin
Published in Journal of cell science (15-08-2006)“…The serine protease urokinase (uPA) binds to the urokinase receptor (uPAR) through its growth-factor domain (GFD, residues 1-49), affecting cell migration,…”
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Journal Article -
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The inhibition of p85[alpha]PI3KSer83 phosphorylation prevents cell proliferation and invasion in prostate cancer cells
Published in Journal of cellular biochemistry (01-09-2013)“…Phosphoinositide 3-kinase proteins are composed by a catalytic p110 subunit and a regulatory p85 subunit. There are three classes of PI3K, named class I-III,…”
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Journal Article -
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AZD3409 inhibits the growth of breast cancer cells with intrinsic resistance to the EGFR tyrosine kinase inhibitor gefitinib
Published in Breast cancer research and treatment (01-05-2007)“…AKT and MAPK signaling are involved in the resistance of breast cancer cells to the EGFR tyrosine kinase inhibitor gefitinib. RAS proteins are upstream…”
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Suppression of HMGA2 protein synthesis could be a tool for the therapy of well differentiated liposarcomas overexpressing HMGA2
Published in Cancer research (Chicago, Ill.) (01-11-2003)“…Atypical lipomatous tumors (ALTs)/well-differentiated liposarcomas represent a distinctive subset of mesenchymal neoplasms featuring mature adipocytic…”
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Journal Article