Search Results - "Ciszewski, Wojciech M"

Whole grain metabolite 3,5-dihydroxybenzoic acid is a beneficial nutritional molecule with the feature of a double-edged sword in human health: a critical review and dietary considerations by Wagner, Waldemar, Sobierajska, Katarzyna, Pułaski, Łukasz, Stasiak, Anna, Ciszewski, Wojciech M.

“…Nonprocessed foodstuffs of plant origin, especially whole-grain cereals, are considered to be health-promoting components of the human diet. While most of…”
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Diverse roles of SARS-CoV-2 Spike and Nucleocapsid proteins in EndMT stimulation through the TGF-β-MRTF axis inhibited by aspirin by Ciszewski, Wojciech M, Woźniak, Lucyna A, Sobierajska, Katarzyna

“…The SARS-CoV-2 virus causes severe COVID-19 in one-fifth of patients. In addition to high mortality, infection may induce respiratory failure and…”
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Correction: Diverse roles of SARS-CoV-2 spike and nucleocapsid proteins in EndMT stimulation through the TGF-β-MRTF axis inhibited by aspirin by Ciszewski, Wojciech M, Woźniak, Lucyna A, Sobierajska, Katarzyna

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The ILK-MMP9-MRTF axis is crucial for EndMT differentiation of endothelial cells in a tumor microenvironment by Ciszewski, Wojciech M., Sobierajska, Katarzyna, Wawro, Marta E., Klopocka, Wanda, Chefczyńska, Natasza, Muzyczuk, Angelika, Siekacz, Kamil, Wujkowska, Agata, Niewiarowska, Jolanta

“…Increasing evidence indicates that the tumor microenvironment is a critical factor supporting cancer progression, chemoresistance and metastasis. Recently,…”
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The New Model of Snail Expression Regulation: The Role of MRTFs in Fast and Slow Endothelial-Mesenchymal Transition by Sobierajska, Katarzyna, Ciszewski, Wojciech M, Macierzynska-Piotrowska, Ewa, Klopocka, Wanda, Przygodzka, Patrycja, Karakula, Magdalena, Pestka, Karolina, Wawro, Marta E, Niewiarowska, Jolanta

“…Endothelial-mesenchymal transition (EndMT) is a crucial phenomenon in regulating the development of diseases, including cancer metastasis and fibrotic…”
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Lactate drives cellular DNA repair capacity: Role of lactate and related short-chain fatty acids in cervical cancer chemoresistance and viral infection by Ciszewski, Wojciech M., Sobierajska, Katarzyna, Stasiak, Anna, Wagner, Waldemar

“…The characteristic feature of a cancer microenvironment is the presence of a highly elevated concentration of L-lactate in the tumor niche. The lactate-rich…”
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TUBB4B Downregulation Is Critical for Increasing Migration of Metastatic Colon Cancer Cells by Sobierajska, Katarzyna, Ciszewski, Wojciech M, Wawro, Marta E, Wieczorek-Szukała, Katarzyna, Boncela, Joanna, Papiewska-Pajak, Izabela, Niewiarowska, Jolanta, Kowalska, M Anna

“…Tumor metastasis, the major problem for clinical oncology in colon cancer treatment, is linked with an epithelial-mesenchymal transition (EMT). The observed…”
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Thymidylate Synthase Overexpression Drives the Invasive Phenotype in Colon Cancer Cells by Ciszewski, Wojciech M, Chmielewska-Kassassir, Ma?gorzata, Wozniak, Lucyna A, Sobierajska, Katarzyna

“…Thymidylate synthase (TYMS) is the crucial enzymatic precursor for DNA biosynthesis and, therefore, the critical target for numerous types of chemotherapy,…”
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Polyphenol Extract from Evening Primrose ( Oenothera paradoxa ) Inhibits Invasion Properties of Human Malignant Pleural Mesothelioma Cells by Chmielewska-Kassassir, Malgorzata, Sobierajska, Katarzyna, Ciszewski, Wojciech M, Bukowiecka-Matusiak, Malgorzata, Szczesna, Dorota, Burzynska-Pedziwiatr, Izabela, Wiczkowski, Wieslaw, Wagner, Waldemar, Wozniak, Lucyna A

“…Extracts from the defatted evening primrose ( Hudziok) seeds are the source of a range of stable polyphenolic compounds, including ellagic acid, gallic acid,…”
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L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation by Wagner, Waldemar, Ciszewski, Wojciech M, Kania, Katarzyna D

“…The consideration of lactate as an active metabolite is a newly emerging and attractive concept. Recently, lactate has been reported to regulate gene…”
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Transforming Growth Factor-β Receptor Internalization via Caveolae Is Regulated by Tubulin-β2 and Tubulin-β3 during Endothelial-Mesenchymal Transition by Sobierajska, Katarzyna, Wawro, Marta E., Ciszewski, Wojciech M., Niewiarowska, Jolanta

“…Fibrotic disorders, which are caused by long-term inflammation, are observed in numerous organs. These disorders are regulated mainly through transforming…”
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DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin by Ciszewski, Wojciech M., Tavecchio, Michele, Dastych, Jarosław, Curtin, Nicola J.

“…DNA-dependent protein kinase (DNA-PK) plays a key role in the repair of DNA double-strand breaks (DSBs) that are probably the most deleterious form of DNA…”
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Stimulation of lactate receptor (HCAR1) affects cellular DNA repair capacity by Wagner, Waldemar, Kania, Katarzyna D., Ciszewski, Wojciech M.

“…•Stimulation of lactate receptor (HCAR1) induces expression of BRCA1 and NBS1.•HCAR1 silencing down-regulates BRCA1 and nibrin protein levels.•HCAR1-diminished…”
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Tubulin beta 3 and 4 are involved in the generation of early fibrotic stages by Wawro, Marta E., Sobierajska, Katarzyna, Ciszewski, Wojciech M., Wagner, Waldemar, Frontczak, Marta, Wieczorek, Katarzyna, Niewiarowska, Jolanta

“…The endothelial-mesenchymal transition (EndMT) is a fundamental cellular mechanism that occurs under both physiological and pathological conditions and…”
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β-III tubulin modulates the behavior of Snail overexpressed during the epithelial-to-mesenchymal transition in colon cancer cells by Sobierajska, Katarzyna, Wieczorek, Katarzyna, Ciszewski, Wojciech M., Sacewicz-Hofman, Izabela, Wawro, Marta E., Wiktorska, Magdalena, Boncela, Joanna, Papiewska-Pajak, Izabela, Kwasniak, Pawel, Wyroba, Elzbieta, Cierniewski, Czeslaw S., Niewiarowska, Jolanta

“…Class III β-tubulin (TUBB3) is a marker of drug resistance expressed in a variety of solid tumors. Originally, it was described as an important element of…”
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Evening Primrose Extract Modulates TYMS Expression via SP1 Transcription Factor in Malignant Pleural Mesothelioma by Chmielewska-Kassassir, Małgorzata, Sobierajska, Katarzyna, Ciszewski, Wojciech M, Kryczka, Jakub, Zieleniak, Andrzej, Wozniak, Lucyna A

“…To determine the mechanism of EPE in downregulating TYMS in MPM cancer. The TYMS mRNA expression with epithelial-to-mesenchymal transition biomarkers and…”
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Colchicine metallocenyl bioconjugates showing high antiproliferative activities against cancer cell lines by Kowalczyk, Karolina, Błauż, Andrzej, Ciszewski, Wojciech M, Wieczorek, Anna, Rychlik, Błażej, Plażuk, Damian

“…A series of ferrocenyl and ruthenocenyl conjugates with colchicine bearing a 1,2,3-triazole moiety were synthesized and their anticancer properties were…”
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Synthesis and in vitro Biological Evaluation of Ferrocenyl Side‐Chain‐Functionalized Paclitaxel Derivatives by Plażuk, Damian, Wieczorek, Anna, Ciszewski, Wojciech M., Kowalczyk, Karolina, Błauż, Andrzej, Pawlędzio, Sylwia, Makal, Anna, Eurtivong, Chatchakorn, Arabshahi, Homayon J., Reynisson, Jóhannes, Hartinger, Christian G., Rychlik, Błażej

“…Taxanes, including paclitaxel, are widely used in cancer therapy. In an attempt to overcome some of the disadvantages entailed with taxane chemotherapy, we…”
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Synthesis and invitro Biological Evaluation of Ferrocenyl Side-Chain-Functionalized Paclitaxel Derivatives by Plauk, Damian, Wieczorek, Anna, Ciszewski, Wojciech M, Kowalczyk, Karolina, Bau, Andrzej, Pawldzio, Sylwia, Makal, Anna, Eurtivong, Chatchakorn, Arabshahi, Homayon J, Reynisson, Jóhannes, Hartinger, Christian G, Rychlik, Baej

“…Taxanes, including paclitaxel, are widely used in cancer therapy. In an attempt to overcome some of the disadvantages entailed with taxane chemotherapy, we…”
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Correction: Diverse roles of SARS-CoV-2 spike and nucleocapsid proteins in EndMT stimulation through the TGF-[beta]-MRTF axis inhibited by aspirin by Ciszewski, Wojciech M, Wo?niak, Lucyna A, Sobierajska, Katarzyna

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