Search Results - "Cisse, I."

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates by Cho, Won-Ki, Spille, Jan-Hendrik, Hecht, Micca, Lee, Choongman, Li, Charles, Grube, Valentin, Cisse, Ibrahim I

“…Models of gene control have emerged from genetic and biochemical studies, with limited consideration of the spatial organization and dynamics of key components…”
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Pol II phosphorylation regulates a switch between transcriptional and splicing condensates by Guo, Yang Eric, Manteiga, John C., Henninger, Jonathan E., Sabari, Benjamin R., Dall’Agnese, Alessandra, Hannett, Nancy M., Spille, Jan-Hendrik, Afeyan, Lena K., Zamudio, Alicia V., Shrinivas, Krishna, Abraham, Brian J., Boija, Ann, Decker, Tim-Michael, Rimel, Jenna K., Fant, Charli B., Lee, Tong Ihn, Cisse, Ibrahim I., Sharp, Phillip A., Taatjes, Dylan J., Young, Richard A.

“…The synthesis of pre-mRNA by RNA polymerase II (Pol II) involves the formation of a transcription initiation complex, and a transition to an elongation complex…”
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A rule of seven in Watson-Crick base-pairing of mismatched sequences by Cisse, Ibrahim I, Kim, Hajin, Ha, Taekjip

“…Sequence recognition through base pairing is essential for DNA repair and gene regulation, but the basic rules underlying this process have been unclear. Data…”
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Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells by Cisse, Ibrahim I., Izeddin, Ignacio, Causse, Sebastien Z., Boudarene, Lydia, Senecal, Adrien, Muresan, Leila, Dugast-Darzacq, Claire, Hajj, Bassam, Dahan, Maxime, Darzacq, Xavier

“…Transcription is reported to be spatially compartmentalized in nuclear transcription factories with clusters of RNA polymerase II (Pol II). However, little is…”
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A dual role for H2A.Z.1 in modulating the dynamics of RNA polymerase II initiation and elongation by Mylonas, Constantine, Lee, Choongman, Auld, Alexander L., Cisse, Ibrahim I., Boyer, Laurie A.

“…RNA polymerase II (RNAPII) pausing immediately downstream of the transcription start site is a critical rate-limiting step for the expression of most metazoan…”
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qSR: a quantitative super-resolution analysis tool reveals the cell-cycle dependent organization of RNA Polymerase I in live human cells by Andrews, J. O., Conway, W., Cho, W -K., Narayanan, A., Spille, J -H., Jayanth, N., Inoue, T., Mullen, S., Thaler, J., Cissé, I. I.

“…We present qSR, an analytical tool for the quantitative analysis of single molecule based super-resolution data. The software is created as an open-source…”
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Hijacking of transcriptional condensates by endogenous retroviruses by Asimi, Vahid, Sampath Kumar, Abhishek, Niskanen, Henri, Riemenschneider, Christina, Hetzel, Sara, Naderi, Julian, Fasching, Nina, Popitsch, Niko, Du, Manyu, Kretzmer, Helene, Smith, Zachary D., Weigert, Raha, Walther, Maria, Mamde, Sainath, Meierhofer, David, Wittler, Lars, Buschow, René, Timmermann, Bernd, Cisse, Ibrahim I., Ameres, Stefan L., Meissner, Alexander, Hnisz, Denes

“…Most endogenous retroviruses (ERVs) in mammals are incapable of retrotransposition; therefore, why ERV derepression is associated with lethality during early…”
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RNA Polymerase II cluster dynamics predict mRNA output in living cells by Cho, Won-Ki, Jayanth, Namrata, English, Brian P, Inoue, Takuma, Andrews, J Owen, Conway, William, Grimm, Jonathan B, Spille, Jan-Hendrik, Lavis, Luke D, Lionnet, Timothée, Cisse, Ibrahim I

“…Protein clustering is a hallmark of genome regulation in mammalian cells. However, the dynamic molecular processes involved make it difficult to correlate…”
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A first order phase transition mechanism underlies protein aggregation in mammalian cells by Narayanan, Arjun, Meriin, Anatoli, Andrews, J Owen, Spille, Jan-Hendrik, Sherman, Michael Y, Cisse, Ibrahim I

“…The formation of misfolded protein aggregates is a hallmark of neurodegenerative diseases. The aggregate formation process exhibits an initial lag phase when…”
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The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance by Dall’Agnese, Alessandra, Platt, Jesse M., Zheng, Ming M., Friesen, Max, Dall’Agnese, Giuseppe, Blaise, Alyssa M., Spinelli, Jessica B., Henninger, Jonathan E., Tevonian, Erin N., Hannett, Nancy M., Lazaris, Charalampos, Drescher, Hannah K., Bartsch, Lea M., Kilgore, Henry R., Jaenisch, Rudolf, Griffith, Linda G., Cisse, Ibrahim I., Jeppesen, Jacob F., Lee, Tong I., Young, Richard A.

“…Insulin receptor (IR) signaling is central to normal metabolic control and is dysregulated in metabolic diseases such as type 2 diabetes. We report here that…”
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Theoretical study of an NH3–H2O absorption chiller powered by a linear Fresnel system modelled by combining ray tracing and CFD by Dione, Fatimata, Thiam, Ababacar, Cisse, ElHadji I., Diouf, Djicknoum, Maiga, Amadou Seidou

“…This paper analyses the performance of a NH3–H2O absorption machine powered with a linear Fresnel reflector. , The various components of the absorption machine…”
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Assessment of radiological hazards from soil samples in the Northeastern area of Burkina Faso by Beogo, Cedric E., Cisse, Ousmane I., Zougmore, Francois

“…The activity concentrations of main naturally occurring radionuclides were determined with the aim of assessing the radiation hazards in the Northeastern part…”
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Experimental investigation of solar chimney with concentrated collector (SCCC) by I Cisse, El Hadji, Thiam, Ababacar, Ndiogou, Baye Alioune, Azilinon, Dorothé, Sambou, Vincent

“…In this article, we have experimentally studied the effect of solar radiation concentration on a solar chimney collector. We analytically measured the…”
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Global analysis of double-strand break processing reveals in vivo properties of the helicase-nuclease complex AddAB by Badrinarayanan, Anjana, Le, Tung B K, Spille, Jan-Hendrik, Cisse, Ibrahim I, Laub, Michael T

“…In bacteria, double-strand break (DSB) repair via homologous recombination is thought to be initiated through the bi-directional degradation and resection of…”
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Heavy metals removal by adsorption onto peanut husks carbon: characterization, kinetic study and modeling by Ricordel, S., Taha, S., Cisse, I., Dorange, G.

“…Carbon prepared from peanut husks (PHC) has been used for the adsorption of Pb 2+, Zn 2+, Ni 2+ and Cd 2+, over a range of initial metal ion concentration…”
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RNA-Mediated Feedback Control of Transcriptional Condensates by Henninger, Jonathan E., Oksuz, Ozgur, Shrinivas, Krishna, Sagi, Ido, LeRoy, Gary, Zheng, Ming M., Andrews, J. Owen, Zamudio, Alicia V., Lazaris, Charalampos, Hannett, Nancy M., Lee, Tong Ihn, Sharp, Phillip A., Cissé, Ibrahim I., Chakraborty, Arup K., Young, Richard A.

“…Regulation of biological processes typically incorporates mechanisms that initiate and terminate the process and, where understood, these mechanisms often…”
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Coactivator condensation at super-enhancers links phase separation and gene control by Sabari, Benjamin R, Dall'Agnese, Alessandra, Boija, Ann, Klein, Isaac A, Coffey, Eliot L, Shrinivas, Krishna, Abraham, Brian J, Hannett, Nancy M, Zamudio, Alicia V, Manteiga, John C, Li, Charles H, Guo, Yang E, Day, Daniel S, Schuijers, Jurian, Vasile, Eliza, Malik, Sohail, Hnisz, Denes, Lee, Tong Ihn, Cisse, Ibrahim I, Roeder, Robert G, Sharp, Phillip A, Chakraborty, Arup K, Young, Richard A

“…Super-enhancers (SEs) are clusters of enhancers that cooperatively assemble a high density of the transcriptional apparatus to drive robust expression of genes…”
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Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes by Zamudio, Alicia V., Dall’Agnese, Alessandra, Henninger, Jonathan E., Manteiga, John C., Afeyan, Lena K., Hannett, Nancy M., Coffey, Eliot L., Li, Charles H., Oksuz, Ozgur, Sabari, Benjamin R., Boija, Ann, Klein, Isaac A., Hawken, Susana W., Spille, Jan-Hendrik, Decker, Tim-Michael, Cisse, Ibrahim I., Abraham, Brian J., Lee, Tong I., Taatjes, Dylan J., Schuijers, Jurian, Young, Richard A.

“…The gene expression programs that define the identity of each cell are controlled by master transcription factors (TFs) that bind cell-type-specific enhancers,…”
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Rayleigh Bénard convective instability of a fluid under high-frequency vibration by Cisse, I., Bardan, G., Mojtabi, A.

“…The generation of two-dimensional thermal convection induced simultaneously by gravity and high-frequency vibration in a bounded rectangular enclosure or in a…”
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Single-molecule tracking in live cells reveals distinct target-search strategies of transcription factors in the nucleus by Izeddin, Ignacio, Récamier, Vincent, Bosanac, Lana, Cissé, Ibrahim I, Boudarene, Lydia, Dugast-Darzacq, Claire, Proux, Florence, Bénichou, Olivier, Voituriez, Raphaël, Bensaude, Olivier, Dahan, Maxime, Darzacq, Xavier

“…Gene regulation relies on transcription factors (TFs) exploring the nucleus searching their targets. So far, most studies have focused on how fast TFs diffuse,…”
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