Search Results - "Cirrone, P."
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Report on G4‐Med, a Geant4 benchmarking system for medical physics applications developed by the Geant4 Medical Simulation Benchmarking Group
Published in Medical physics (Lancaster) (01-01-2021)“…Background Geant4 is a Monte Carlo code extensively used in medical physics for a wide range of applications, such as dosimetry, micro‐ and nanodosimetry,…”
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First design of a crystal-based extraction of 6 GeV electrons for the DESY II Booster Synchrotron
Published in The European physical journal. C, Particles and fields (01-03-2022)“…A proof-of-principle experimental setup for the extraction of 6 GeV electrons from the DESY II Booster Synchrotron using the channeling effect in a bent…”
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3
Effects of Ion Irradiation on Seedlings Growth Monitored by Ultraweak Delayed Luminescence
Published in PloS one (09-12-2016)“…The optical technique based on the measurement of delayed luminescence emitted from the biological samples has demonstrated its ability to provide valid and…”
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First experimental proof of Proton Boron Capture Therapy (PBCT) to enhance protontherapy effectiveness
Published in Scientific reports (18-01-2018)“…Protontherapy is hadrontherapy’s fastest-growing modality and a pillar in the battle against cancer. Hadrontherapy’s superiority lies in its inverted…”
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5
Molecular Investigation on a Triple Negative Breast Cancer Xenograft Model Exposed to Proton Beams
Published in International journal of molecular sciences (01-09-2020)“…Specific breast cancer (BC) subtypes are associated with bad prognoses due to the absence of successful treatment plans. The triple-negative breast cancer…”
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Proton Therapy and Src Family Kinase Inhibitor Combined Treatments on U87 Human Glioblastoma Multiforme Cell Line
Published in International journal of molecular sciences (24-09-2019)“…Glioblastoma Multiforme (GBM) is the most common of malignant gliomas in adults with an exiguous life expectancy. Standard treatments are not curative and the…”
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Proton Acceleration Driven by a Nanosecond Laser from a Cryogenic Thin Solid-Hydrogen Ribbon
Published in Physical review. X (01-11-2016)“…A high-power pulsed laser is focused onto a solid-hydrogen target to accelerate forward a collimated stream of protons in the range 0.1–1 MeV, carrying a very…”
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Different Mechanisms Underlie the Metabolic Response of GBM Stem-Like Cells to Ionizing Radiation: Biological and MRS Studies on Effects of Photons and Carbon Ions
Published in International journal of molecular sciences (21-07-2020)“…Glioblastoma multiforme (GBM) is a malignant primary brain tumor with very poor prognosis, high recurrence rate, and failure of chemo-radiotherapy, mainly due…”
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Development of a portable hypoxia chamber for ultra-high dose rate laser-driven proton radiobiology applications
Published in Radiation oncology (London, England) (15-04-2022)“…There is currently significant interest in assessing the role of oxygen in the radiobiological effects at ultra-high dose rates. Oxygen modulation is…”
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Generation of α-Particle Beams With a Multi-kJ, Peta-Watt Class Laser System
Published in Frontiers in physics (09-09-2020)“…We present preliminary results on generation of energetic α-particles driven by lasers. The experiment was performed at the Institute of Laser Engineering in…”
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Perspectives in linear accelerator for FLASH VHEE: Study of a compact C-band system
Published in Physica medica (01-12-2022)“…In order to translate the FLASH effect in clinical use and to treat deep tumors, Very High Electron Energy irradiations could represent a valid technique…”
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12
Repeatability and Reproducibility of Microdosimetry With a Mini-TEPC
Published in Frontiers in physics (13-08-2021)“…Experimental microdosimetry measures the energy deposited in a microscopic sensitive volume ( SV ) by single ionizing particles traversing the SV or passing…”
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Fluence Beam Monitor for High-Intensity Particle Beams Based on a Multi-Gap Ionization Chamber and a Method for Ion Recombination Correction
Published in Applied sciences (01-12-2022)“…This work presents the tests of a multi-gap detector (MGD), composed of three parallel-plate ionization chambers (ICs) with different gap widths, assembled to…”
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Carbon fragmentation measurements and validation of the Geant4 nuclear reaction models for hadrontherapy
Published in Physics in medicine & biology (21-11-2012)“…Nuclear fragmentation measurements are necessary when using heavy-ion beams in hadrontherapy to predict the effects of the ion nuclear interactions within the…”
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Clinical and Research Activities at the CATANA Facility of INFN-LNS: From the Conventional Hadrontherapy to the Laser-Driven Approach
Published in Frontiers in oncology (19-09-2017)“…The CATANA proton therapy center was the first Italian clinical facility making use of energetic (62 MeV) proton beams for the radioactive treatment of solid…”
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The ELIMAIA Laser–Plasma Ion Accelerator: Technological Commissioning and Perspectives
Published in Quantum beam science (01-12-2022)“…We report on the technological commissioning of the Laser–Plasma Ion Accelerator section of the ELIMAIA user beamline at the ELI Beamlines facility in the…”
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Role of laser contrast and foil thickness in target normal sheath acceleration
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (01-09-2016)“…In this paper we present an experimental investigation of laser driven light-ion acceleration using the ILIL laser at an intensity of 2×1019W/cm2. In the…”
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Spectral and spatial shaping of a laser-produced ion beam for radiation-biology experiments
Published in Physical review. Accelerators and beams (02-03-2017)“…The study of radiation biology on laser-based accelerators is most interesting due to the unique irradiation conditions they can produce, in terms of peak…”
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Hypoxia Transcriptomic Modifications Induced by Proton Irradiation in U87 Glioblastoma Multiforme Cell Line
Published in Journal of personalized medicine (16-04-2021)“…In Glioblastoma Multiforme (GBM), hypoxia is associated with radioresistance and poor prognosis. Since standard GBM treatments are not always effective, new…”
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STUDY FOR A PASSIVE SCATTERING LINE DEDICATED TO RADIOBIOLOGY EXPERIMENTS AT THE TRENTO PROTON THERAPY CENTER
Published in Radiation protection dosimetry (01-05-2019)“…The recent worldwide spread of Proton Therapy centers paves the way to new opportunities for basic and applied research related to the use of accelerated…”
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