Search Results - "Cirovic, Branko"

BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment by Cirovic, Branko, de Bree, L. Charlotte J., Groh, Laszlo, Blok, Bas A., Chan, Joyce, van der Velden, Walter J.F.M., Bremmers, M.E.J., van Crevel, Reinout, Händler, Kristian, Picelli, Simone, Schulte-Schrepping, Jonas, Klee, Kathrin, Oosting, Marije, Koeken, Valerie A.C.M., van Ingen, Jakko, Li, Yang, Benn, Christine S., Schultze, Joachim L., Joosten, Leo A.B., Curtis, Nigel, Netea, Mihai G., Schlitzer, Andreas

“…Induction of trained immunity by Bacille-Calmette-Guérin (BCG) vaccination mediates beneficial heterologous effects, but the mechanisms underlying its…”
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BCG vaccination in humans inhibits systemic inflammation in a sex-dependent manner by Koeken, Valerie Acm, de Bree, L Charlotte J, Mourits, Vera P, Moorlag, Simone Jcfm, Walk, Jona, Cirovic, Branko, Arts, Rob Jw, Jaeger, Martin, Dijkstra, Helga, Lemmers, Heidi, Joosten, Leo Ab, Benn, Christine S, van Crevel, Reinout, Netea, Mihai G

“…BACKGROUNDInduction of innate immune memory, also termed trained immunity, by the antituberculosis vaccine bacillus Calmette-Guérin (BCG) contributes to…”
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β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32 by dos Santos, Jéssica Cristina, Barroso de Figueiredo, Ana Marina, Teodoro Silva, Muriel Vilela, Cirovic, Branko, de Bree, L. Charlotte J., Damen, Michelle S.M.A., Moorlag, Simone J.C.F.M., Gomes, Rodrigo S., Helsen, Monique M., Oosting, Marije, Keating, Samuel T., Schlitzer, A., Netea, Mihai G., Ribeiro-Dias, Fátima, Joosten, Leo A.B.

“…American tegumentary leishmaniasis is a vector-borne parasitic disease caused by Leishmania protozoans. Innate immune cells undergo long-term functional…”
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Reply to: ‘Lack of evidence for intergenerational inheritance of immune resistance to infections’ by Katzmarski, Natalie, Domínguez-Andrés, Jorge, Cirovic, Branko, Renieris, Georgios, Ciarlo, Eleonora, Le Roy, Didier, Lepikhov, Konstantin, Kattler, Kathrin, Gasparoni, Gilles, Händler, Kristian, Theis, Heidi, Beyer, Marc, van der Meer, Jos W. M., Joosten, Leo A. B., Walter, Jörn, Schultze, Joachim L., Roger, Thierry, Giamarellos-Bourboulis, Evangelos J., Schlitzer, Andreas, Netea, Mihai G.

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Correction: CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells by Drachsler, Moritz, Kleber, Susanne, Mateos, Alvaro, Volk, Katrin, Mohr, Nadine, Chen, Si, Cirovic, Branko, Tüttenberg, Jochen, Gieffers, Christian, Sykora, Jaromir, Wirtz, Christian, Mueller, Wolf, Synowitz, Michael, Martin-Villalba, Ana

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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A Runx1 Intronic Enhancer Marks Hemogenic Endothelial Cells and Hematopoietic Stem Cells by Ng, Cherry Ee Lin, Yokomizo, Tomomasa, Yamashita, Namiko, Cirovic, Branko, Jin, Hao, Wen, Zilong, Ito, Yoshiaki, Osato, Motomi

“…Runx1 is essential for the generation of hematopoietic stem cells (HSCs) and is frequently mutated in human leukemias. However, the cis‐regulatory mechanisms…”
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Immune competence and spleen size scale with colony status in the naked mole-rat by Bégay, Valérie, Cirovic, Branko, Barker, Alison J, Klopfleisch, Robert, Hart, Daniel W, Bennett, Nigel C, Lewin, Gary R

“…Naked mole-rats (NM-R; ) live in multi-generational colonies with a social hierarchy, and show low cancer incidence and long life-spans. Here we asked if an…”
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C/EBP-Induced Transdifferentiation Reveals Granulocyte-Macrophage Precursor-like Plasticity of B Cells by Cirovic, Branko, Schönheit, Jörg, Kowenz-Leutz, Elisabeth, Ivanovska, Jelena, Klement, Christine, Pronina, Nina, Bégay, Valérie, Leutz, Achim

“…The lymphoid-myeloid transdifferentiation potentials of members of the C/EBP family (C/EBPα, β, δ, and ε) were compared in v-Abl-immortalized primary B cells…”
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Analysis of High-Dimensional Phenotype Data Generated by Mass Cytometry or High-Dimensional Flow Cytometry by Cirovic, Branko, Katzmarski, Natalie, Schlitzer, Andreas

“…Recent advances in single cell multi-omics methodologies significantly expand our understanding of cellular heterogeneity, particularly in the field of…”
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Transmission of trained immunity and heterologous resistance to infections across generations by Katzmarski, Natalie, Domínguez-Andrés, Jorge, Cirovic, Branko, Renieris, Georgios, Ciarlo, Eleonora, Le Roy, Didier, Lepikhov, Konstantin, Kattler, Kathrin, Gasparoni, Gilles, Händler, Kristian, Theis, Heidi, Beyer, Marc, van der Meer, Jos W. M., Joosten, Leo A. B., Walter, Jörn, Schultze, Joachim L., Roger, Thierry, Giamarellos-Bourboulis, Evangelos J., Schlitzer, Andreas, Netea, Mihai G.

“…Intergenerational inheritance of immune traits linked to epigenetic modifications has been demonstrated in plants and invertebrates. Here we provide evidence…”
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Flt3- and Tie2-Cre tracing identifies regeneration in sepsis from multipotent progenitors but not hematopoietic stem cells by Fanti, Ann-Kathrin, Busch, Katrin, Greco, Alessandro, Wang, Xi, Cirovic, Branko, Shang, Fuwei, Nizharadze, Tamar, Frank, Larissa, Barile, Melania, Feyerabend, Thorsten B., Höfer, Thomas, Rodewald, Hans-Reimer

“…In response to infections and stress, hematopoiesis rapidly enhances blood and immune cell production. The stage within the hematopoietic hierarchy that…”
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Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2 by Sander, Jil, Schmidt, Susanne V., Cirovic, Branko, McGovern, Naomi, Papantonopoulou, Olympia, Hardt, Anna-Lena, Aschenbrenner, Anna C., Kreer, Christoph, Quast, Thomas, Xu, Alexander M., Schmidleithner, Lisa M., Theis, Heidi, Thi Huong, Lan Do, Sumatoh, Hermi Rizal Bin, Lauterbach, Mario A.R., Schulte-Schrepping, Jonas, Günther, Patrick, Xue, Jia, Baßler, Kevin, Ulas, Thomas, Klee, Kathrin, Katzmarski, Natalie, Herresthal, Stefanie, Krebs, Wolfgang, Martin, Bianca, Latz, Eicke, Händler, Kristian, Kraut, Michael, Kolanus, Waldemar, Beyer, Marc, Falk, Christine S., Wiegmann, Bettina, Burgdorf, Sven, Melosh, Nicholas A., Newell, Evan W., Ginhoux, Florent, Schlitzer, Andreas, Schultze, Joachim L.

“…Human in vitro generated monocyte-derived dendritic cells (moDCs) and macrophages are used clinically, e.g., to induce immunity against cancer. However, their…”
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Integrin-α9 overexpression underlies the niche-independent maintenance of leukemia stem cells in acute myeloid leukemia by Niibori-Nambu, Akiko, Wang, Chelsia Qiuxia, Chin, Desmond Wai Loon, Chooi, Jing Yuan, Hosoi, Hiroki, Sonoki, Takashi, Tham, Cheng-Yong, Nah, Giselle Sek Suan, Cirovic, Branko, Tan, Darren Qiancheng, Takizawa, Hitoshi, Sashida, Goro, Goh, Yufen, Tng, Jiaqi, Fam, Wee Nih, Fullwood, Melissa Jane, Suda, Toshio, Yang, Henry, Tergaonkar, Vinay, Taniuchi, Ichiro, Li, Shang, Chng, Wee Joo, Osato, Motomi

“…•ITGA9 is a leukemic stem cell marker in AML.•ITGA9 overexpression activates p38MAPK and AKT signaling pathways and elevates MYC expression.•The soluble…”
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Author Correction: Transmission of trained immunity and heterologous resistance to infections across generations by Katzmarski, Natalie, Domínguez-Andrés, Jorge, Cirovic, Branko, Renieris, Georgios, Ciarlo, Eleonora, Le Roy, Didier, Lepikhov, Konstantin, Kattler, Kathrin, Gasparoni, Gilles, Händler, Kristian, Theis, Heidi, Beyer, Marc, van der Meer, Jos W. M., Joosten, Leo A. B., Walter, Jörn, Schultze, Joachim L., Roger, Thierry, Giamarellos-Bourboulis, Evangelos J., Schlitzer, Andreas, Netea, Mihai G.

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