Search Results - "Cirkel, Deborah T."

HARMONY 3:104-Week Randomized, Double-Blind, Placebo- and Active-Controlled Trial Assessing the Efficacy and Safety of Albiglutide Compared With Placebo, Sitagliptin, and Glimepiride in Patients With Type 2 Diabetes Taking Metformin by AHREN, Bo, JOHNSON, Susan L, STEWART, Murray, CIRKEL, Deborah T, YANG, Fred, PERRY, Caroline, FEINGLOS, Mark N

“…To compare the efficacy and safety of weekly albiglutide with daily sitagliptin, daily glimepiride, and placebo. Patients with type 2 diabetes receiving…”
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HARMONY 4: randomised clinical trial comparing once-weekly albiglutide and insulin glargine in patients with type 2 diabetes inadequately controlled with metformin with or without sulfonylurea by Weissman, Peter N., Carr, Molly C., Ye, June, Cirkel, Deborah T., Stewart, Murray, Perry, Caroline, Pratley, Richard

“…Aims/hypothesis The aim of this study was to compare the efficacy and safety of once-weekly albiglutide with once-daily insulin glargine (A21Gly,B31Arg,B32Arg…”
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Three-year data from 5 HARMONY phase 3 clinical trials of albiglutide in type 2 diabetes mellitus: long-term efficacy with or without rescue therapy by Home, Philip D, Ahrén, Bo, Reusch, Jane E.B, Rendell, Marc, Weissman, Peter N, Cirkel, Deborah T, Miller, Diane, Ambery, Philip, Carr, Molly C, Nauck, Michael A

“…Highlights • Efficacy results from five 3-year, phase 3 trials of the GLP-1RA albiglutide. • Less hyperglycaemic rescue needed with albiglutide vs placebo ( p…”
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Low-Dose Oral Fluorouracil With Eniluracil as First-Line Chemotherapy Against Advanced Breast Cancer: A Phase II Study by Smith, I E, Johnston, S R, O'Brien, M E, Hickish, T F, de Boer, R H, Norton, A, Cirkel, D T, Barton, C M

“…Eniluracil (776C85) is an effective inactivator of dihydropyrimidine dehydrogenase that allows continuous low-dose oral fluorouracil (5-FU) to be given with…”
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