Search Results - "Circulatory shock"

Evidence of increased nitric oxide production in patients with the sepsis syndrome by Evans, T, Carpenter, A, Kinderman, H, Cohen, J

“…To investigate whether the hypotension of septic shock is due to an excess production of nitric oxide (NO), we have determined the serum levels of nitrate and…”
Get more information

Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody by Taylor, Jr, F B, Chang, A, Ruf, W, Morrissey, J H, Hinshaw, L, Catlett, R, Blick, K, Edgington, T S

“…Gram-negative bacteremia poses a major health problem, causing one-half of cases of lethal septic shock acquired during hospitalization. Bacterial…”
Get more information

The Pericardium Substantially Affects the Left Ventricular Diastolic Pressure-Volume Relationship in the Dog by GLANTZ, STANTON A, MISBACH, GREGORY A, MOORES, WILLIAM Y, MATHEY, DETLEF G, LEKVEN, JON, STOWE, DAVID F, PARMLEY, WILLIAM W, TYBERG, JOHN V

“…We instrumented six dog hearts in vivo to study the relationship between left and right ventricular diastolic pressures with the pericardium closed and open…”
Get full text

Studies of the Release from Human Platelets of the Growth Factor for Cultured Human Arterial Smooth Muscle Cells by WITTE, LARRY D, KAPLAN, KAREN L, NOSSEL, HYMIE L, LAGES, BRUCE A, WEISS, HARVEY J, GOODMAN, DEWITT S

“…Platelets contain a growth-promoting factor for arterial smooth muscle cells (SMC) that may play a major role in atberogenesis. We have studied some of the…”
Get full text

Human responses to bacterial endotoxin by Burrell, R

“…The literature concerning human responses to bacterial endotoxin, in particular to the purified lipopolysaccharide derivative, has been critically reviewed and…”
Get more information

Recombinant E. coli-derived tissue factor pathway inhibitor reduces coagulopathic and lethal effects in the baboon gram-negative model of septic shock by Carr, C, Bild, G S, Chang, A C, Peer, G T, Palmier, M O, Frazier, R B, Gustafson, M E, Wun, T C, Creasey, A A, Hinshaw, L B

“…Excessive coagulation is a typical response to the vascular injury occurring in gram negative sepsis. This study evaluated the pharmacological effects of the…”
Get more information

Evidence that neural mechanisms do not have important effects on cerebral blood flow by Heistad, D D, Marcus, M L

Get full text

Survival of primates in LD100 septic shock following therapy with antibody to tumor necrosis factor (TNF alpha) by Hinshaw, L B, Tekamp-Olson, P, Chang, A C, Lee, P A, Taylor, Jr, F B, Murray, C K, Peer, G T, Emerson, Jr, T E, Passey, R B, Kuo, G C

“…The purpose of this study was to determine the efficacy of treatment with anti-TNF monoclonal antibody in preventing the deleterious effects of sepsis in a…”
Get more information

Quantitative Determination of Regional Oxygen Consumption in the Dog Heart by WEISS, HARVEY R, NEUBAUER, JUDITH A, LIPP, J A, SINHA, A K

“…A micro-Fick method has been developed to measure the O, consumption of different region* of an organ. The method was tested in isolated dog gracilis muscle…”
Get full text

Circulating cytokines: the tip of the iceberg? by Cavaillon, J M, Munoz, C, Fitting, C, Misset, B, Carlet, J

“…Circulating cytokines, particularly TNF alpha, IL-1, IL-6 and IL-8, can be detected during severe infections consecutively to an exacerbate release by…”
Get more information

Liver and Ductus Venosus Blood Flows in Fetal Lambs in Utero by EDELSTONE, DANIEL I, RUDOLPH, ABRAHAM M, HEYMANN, MICHAEL A

“…We evaluated the circulation of the liver and ductus venosus, using the radionuclide-labeled mkrosphere technique, in 24 chronically prepared fetal lambs. We…”
Get full text

Hypertonic saline enhances cellular immune function by Junger, W G, Liu, F C, Loomis, W H, Hoyt, D B

“…Hypertonic saline (HTS) resuscitation improves outcome after trauma. We studied the effect of HTS on immune function. In vitro T-cell proliferation of human…”
Get more information

Elevated plasma levels of endothelin in patients with sepsis syndrome by Weitzberg, E, Lundberg, J M, Rudehill, A

“…The levels of the recently isolated endothelial-derived peptide, endothelin, which has potent vasoconstrictor properties, were analyzed by radioimmunoassay in…”
Get more information

Hypothermia and blood coagulation: dissociation between enzyme activity and clotting factor levels by Reed, 2nd, R L, Bracey, Jr, A W, Hudson, J D, Miller, T A, Fischer, R P

“…Previous studies of hypothermia and blood coagulation have focused on alterations in the levels of blood clotting elements using coagulation tests performed…”
Get more information

Capillary narrowing in hemorrhagic shock is rectified by hyperosmotic saline-dextran reinfusion by Mazzoni, M C, Borgström, P, Intaglietta, M, Arfors, K E

“…Previously, we showed that skeletal muscle capillaries narrow during hemorrhagic shock due to swelling of endothelial cells. The present study investigated if…”
Get more information

Altered mitochondrial redox responses in gram negative septic shock in primates by Simonson, S G, Welty-Wolf, K, Huang, Y T, Griebel, J A, Caplan, M S, Fracica, P J, Piantadosi, C A

“…Gram negative sepsis causes changes in oxygen supply-demand relationships. We have used a primate model of hyperdynamic gram negative sepsis produced by…”
Get more information

Changes in tissue antioxidant enzyme activities and lipid peroxides in endotoxin-induced multiple organ failure by Yoshikawa, T, Takano, H, Takahashi, S, Ichikawa, H, Kondo, M

“…Intravenous administration of bacterial endotoxin (lipopolysaccharide: LPS) induces shock and disseminated intravascular coagulation in rats. Our report here…”
Get more information

Polymicrobial sepsis selectively activates peritoneal but not alveolar macrophages to release inflammatory mediators (interleukins-1 and -6 and tumor necrosis factor) by Ayala, A, Perrin, M M, Kisala, J M, Ertel, W, Chaudry, I H

“…While a number of clinical studies indicate that elevated serum cytokine [interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor (TNF)] levels…”
Get more information

Pentoxifylline increases survival in murine endotoxin shock and decreases formation of tumor necrosis factor by Schade, U F

“…Pentoxifylline (POF) was found to possess high protecting potential in murine endotoxin shock. POF was tested in endotoxic shock in normal, LPS-tolerant,…”
Get more information

Tumor necrosis factor (cachectin) in the biology of septic shock syndrome by Tracey, K J

“…The high mortality of septic shock syndrome has prompted extensive investigation into its pathogenesis. Tumor necrosis factor (TNF), a cytokine that is often…”
Get more information