Search Results - "Cipolla, J."

The importance of comorbidities in ischemic stroke: Impact of hypertension on the cerebral circulation by Cipolla, Marilyn J, Liebeskind, David S, Chan, Siu-Lung

“…Comorbidities are a hallmark of stroke that both increase the incidence of stroke and worsen outcome. Hypertension is prevalent in the stroke population and…”
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Melatonin, energy metabolism, and obesity: a review by Cipolla-Neto, J., Amaral, F. G., Afeche, S. C., Tan, D. X., Reiter, R. J.

“…Melatonin is an old and ubiquitous molecule in nature showing multiple mechanisms of action and functions in practically every living organism. In mammals,…”
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Inhibition of PAI (Plasminogen Activator Inhibitor)-1 Improves Brain Collateral Perfusion and Injury After Acute Ischemic Stroke in Aged Hypertensive Rats by Chan, Siu-Lung, Bishop, Nicole, Li, Zhaojin, Cipolla, Marilyn J

“…BACKGROUND AND PURPOSE—Aging and hypertension, comorbidities prevalent in the stroke population, are associated with poor collateral status and worsened stroke…”
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Advanced glycation end products alter steroidogenic gene expression by granulosa cells: an effect partially reversible by vitamin D by Merhi, Z, Buyuk, E, Cipolla, M J

“…Abstract STUDY QUESTION Does vitamin D attenuate the adverse effects of advanced glycation end products (AGEs) on steroidogenesis by human granulosa cells…”
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Stroke in Pregnancy and Preeclampsia: Effect of Low-Dose Aspirin Treatment on Collateral Flow Velocity and Cerebral Blood Flow Autoregulation During Ischemia in Rats by Cipolla, Marilyn J, Tremble, Sarah M

“…Experimental preeclampsia (ePE) has been shown to have worsened outcome from stroke. We investigated the effect of low-dose aspirin, known to prevent…”
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Pharmacologically increasing collateral perfusion during acute stroke using a carboxyhemoglobin gas transfer agent (Sanguinate™) in spontaneously hypertensive rats by Cipolla, Marilyn J, Linfante, Italo, Abuchowski, Abe, Jubin, Ronald, Chan, Siu-Lung

“…Similar to patients with chronic hypertension, spontaneously hypertensive rats (SHR) develop fast core progression during middle cerebral artery occlusion…”
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The cerebral circulation during pregnancy: adapting to preserve normalcy by Johnson, Abbie C, Cipolla, Marilyn J

“…The adaptation of the brain and cerebral circulation to pregnancy are unique compared with other organs and circulatory systems, ultimately functioning to…”
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Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia by Johnson, Abbie Chapman, Tremble, Sarah M, Chan, Siu-Lung, Moseley, Janae, LaMarca, Babbette, Nagle, Keith J, Cipolla, Marilyn J

“…Eclampsia, defined as unexplained seizure in a woman with preeclampsia, is a life-threatening complication of pregnancy with unclear etiology. Magnesium…”
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Experimental Preeclampsia Causes Long-Lasting Hippocampal Vascular Dysfunction and Memory Impairment by Johnson, Abbie C, Tremble, Sarah M, Cipolla, Marilyn J

“…Preeclampsia (PE) is a hypertensive disorder of pregnancy that is associated with memory impairment, cognitive decline and brain atrophy later in life in women…”
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Environmental Control of Biological Rhythms: Effects on Development, Fertility and Metabolism by Amaral, F. G., Castrucci, A. M., Cipolla-Neto, J., Poletini, M. O., Mendez, N., Richter, H. G., Sellix, M. T.

“…Internal temporal organisation properly synchronised to the environment is crucial for health maintenance. This organisation is provided at the cellular level…”
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Differential effect of gold nanoparticles on cerebrovascular function and biomechanical properties by Hunt, Ryan D., Sedighi, Omid, Clark, Wayne M., Doiron, Amber L., Cipolla, Marilyn J.

“…Human stroke serum (HSS) has been shown to impair cerebrovascular function, likely by factors released into the circulation after ischemia. 20 nm gold…”
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The impact of collateral therapeutics on stroke hemodynamics in normotensive and hypertensive rats: a step toward translation by Cipolla, Marilyn J, Hunt, Ryan D, Liebeskind, David S, Tremble, Sarah M

“…Stroke interventions that increase collateral flow have the potential to salvage penumbral tissue and increase the number of patients eligible for reperfusion…”
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Daily differential expression of melatonin-related genes and clock genes in rat cumulus-oocyte complex: changes after pinealectomy by Coelho, L. A., Peres, R., Amaral, F. G., Reiter, R. J., Cipolla-Neto, J.

“…This study investigated the maturational stage (immature and mature ovaries) differences of mRNA expression of melatonin‐forming enzymes (Aanat and Asmt),…”
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Retrospective study of medical student scholarship and career trajectory following a mentored preclinical cardiovascular summer research fellowship by Wahlberg, Kramer, Mughal, Amreen, Li, Zhaojin, Cipolla, Marilyn J, Cushman, Mary, Flyer, Jonathan N

“…ObjectivesDeveloping a preclinical training infrastructure for cardiovascular clinician-scientists is an academic workforce priority. The Cardiovascular…”
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Effect of hypertension and carotid occlusion on brain parenchymal arteriole structure and reactivity by Sweet, Julie G, Chan, Siu-Lung, Cipolla, Marilyn J

“…We studied the effect of hypertension and chronic hypoperfusion on brain parenchymal arteriole (PA) structure and function. PAs were studied isolated and…”
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Mechanical signaling through connective tissue: a mechanism for the therapeutic effect of acupuncture by Langevin, Helene M., Churchill, David L., Cipolla, Marilyn J.

“…The mechanism of action of acupuncture remains largely unknown. The reaction to acupuncture needling known as ‘de qi’, widely viewed as essential to the…”
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Increased oxidized low‐density lipoprotein causes blood‐brain barrier disruption in early‐onset preeclampsia through LOX‐1 by Schreurs, Malou P. H., Hubel, Carl A., Bernstein, Ira M., Jeyabalan, Arun, Cipolla, Marilyn J.

“…Early‐onset preeclampsia (EPE) is a severe form of preeclampsia that involves life‐threatening neurological complications. However, the underlying mechanism by…”
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The Contribution of Normal Pregnancy to Eclampsia by Johnson, Abbie Chapman, Nagle, Keith J, Tremble, Sarah M, Cipolla, Marilyn J

“…Eclampsia, clinically defined as unexplained seizure in a woman with preeclampsia, is a life threatening complication unique to the pregnant state. However, a…”
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From FAST to E-FAST: an overview of the evolution of ultrasound-based traumatic injury assessment by Montoya, J., Stawicki, S. P., Evans, D. C., Bahner, D. P., Sparks, S., Sharpe, R. P., Cipolla, J.

“…Ultrasound is a ubiquitous and versatile diagnostic tool. In the setting of acute injury, ultrasound enhances the basic trauma evaluation, influences bedside…”
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Dilation of Pregnant Rat Uterine Arteries with Phenols from Extra Virgin Olive Oil Is Endothelium-Dependent and Involves Calcium and Potassium Channels by Esposito, Milena, Gatto, Mariacarmela, Cipolla, Marilyn J, Bernstein, Ira M, Mandalà, Maurizio

“…During pregnancy, uterine vasculature undergoes significant circumferential growth to increase uterine blood flow, vital for the growing feto-placental unit…”
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