Search Results - "Ciotti, MT"

NMDA Receptor Mediates Tau-Induced Neurotoxicity by Calpain and ERK/MAPK Activation by Amadoro, Giuseppina, Ciotti, Maria Teresa, Costanzi, Marco, Cestari, Vincenzo, Calissano, Pietro, Canu, Nadia

“…The altered function and/or structure of tau protein is postulated to cause cell death in tauopathies and Alzheimer's disease. However, the mechanisms by which…”
Get full text

Role of the autophagic‐lysosomal system on low potassium‐induced apoptosis in cultured cerebellar granule cells by Canu, Nadia, Tufi, Roberta, Serafino, Anna Lucia, Amadoro, Giuseppina, Ciotti, Maria Teresa, Calissano, Pietro

“…Apoptotic and autophagic cell death have been implicated, on the basis of morphological and biochemical criteria, in neuronal loss occurring in…”
Get full text

Ligand-independent CXCR2 Dimerization by Trettel, Flavia, Di Bartolomeo, Sabrina, Lauro, Clotilde, Catalano, Myriam, Ciotti, Maria Teresa, Limatola, Cristina

“…Homo- and hetero-oligomerization have been reported for several G protein-coupled receptors (GPCRs). The CXCR2 is a GPCR that is activated, among the others,…”
Get full text

Tau Cleavage and Dephosphorylation in Cerebellar Granule Neurons Undergoing Apoptosis by Canu, Nadia, Dus, Laura, Barbato, Christian, Ciotti, Maria T, Brancolini, Claudio, Rinaldi, Anna M, Novak, Michal, Cattaneo, Antonino, Bradbury, Andrew, Calissano, Pietro

“…Cerebellar granule cells undergo apoptosis in culture after deprivation of potassium and serum. During this process we found that tau, a neuronal…”
Get full text

Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells by Zona, Cristina, Teresa Ciotti, Maria, Avoli, Massimo

“…Whole-cell, voltage-clamp recordings were made from rat cerebellar granule cells in culture under experimental conditions designed to study voltage-gated Na +…”
Get full text

Tachykinin neuropeptides in cerebellar granule neurons: an immunocytochemical study by Barbato, C, Ciotti, M T, Serafino, A, Severini, C, Calissano, P

“…We previously demonstrated that exogenously administered neurokinin A and neurokinin B, but not substance P, increased the sensitivity of cultured cerebellar…”
Get full text

Oxidative stress induces p53-mediated apoptosis in glia: p53 transcription-independent way to die by Bonini, Paolo, Cicconi, Simona, Cardinale, Alessio, Vitale, Cristiana, Serafino, Anna Lucia, Ciotti, Maria Teresa, Marlier, Lionel N.J-L.

“…Oxidative stress has been implicated in the pathogenesis of stroke, traumatic brain injuries, and neurodegenerative diseases affecting both neuronal and glial…”
Get full text

Proteasome Involvement and Accumulation of Ubiquitinated Proteins in Cerebellar Granule Neurons Undergoing Apoptosis by Canu, Nadia, Barbato, Christian, Ciotti, Maria Teresa, Serafino, Annalucia, Dus, Laura, Calissano, Pietro

“…We investigated the potential role of the ubiquitin proteolytic system in the death of cerebellar granule neurons induced by reduction of extracellular…”
Get full text

Dual Control of Neurogenesis by PC3 through Cell Cycle Inhibition and Induction of Math1 by Canzoniere, Daniela, Farioli-Vecchioli, Stefano, Conti, Filippo, Ciotti, Maria Teresa, Tata, Ada Maria, Augusti-Tocco, Gabriella, Mattei, Elisabetta, Lakshmana, Madepalli K, Krizhanovsky, Valery, Reeves, Steven A, Giovannoni, Roberto, Castano, Francesca, Servadio, Antonio, Ben-Arie, Nissim, Tirone, Felice

“…Growing evidence indicates that cell cycle arrest and neurogenesis are highly coordinated and interactive processes, governed by cell cycle genes and neural…”
Get full text

Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons by Amadoro, G, Serafino, A L, Barbato, C, Ciotti, M T, Sacco, A, Calissano, P, Canu, N

“…Although the role of the microtubule-binding domain of the tau protein in the modulation of microtubule assembly is widely established, other possible…”
Get full text

Gadolinium in human glioblastoma cells for gadolinium neutron capture therapy by DE STASIO, Gelsomina, CASALBORE, Patrizia, PERRET, Didier, MOGK, David W, PERFETTI, Paolo, MEHTA, Minesh P, MERCANTI, Delio, PALLINI, Roberto, GILBERT, Benjamin, SANITA, Francesca, CIOTTI, Maria Teresa, ROSI, Giancarlo, FESTINESI, Armando, LAROCCA, Luigi Maria, RINELLI, Alessandro

“…157Gd is a potential agent for neutron capture cancer therapy (GdNCT). We directly observed the microdistribution of Gd in cultured human glioblastoma cells…”
Get full text

Signalling pathways involved in the chemotactic activity of CXCL12 in cultured rat cerebellar neurons and CHP100 neuroepithelioma cells by Floridi, Francesca, Trettel, Flavia, Di Bartolomeo, Sabrina, Ciotti, Maria Teresa, Limatola, Cristina

“…We compared the signal transduction pathways activated by stromal cell-derived factor-1 (CXCL12) chemokine in two different cell systems: primary cultures of…”
Get full text

SDF-1α-mediated modulation of synaptic transmission in rat cerebellum by Limatola, Cristina, Giovannelli, Aldo, Maggi, Laura, Ragozzino, Davide, Castellani, Loriana, Ciotti, Maria Teresa, Vacca, Fabrizio, Mercanti, Delio, Santoni, Angela, Eusebi, Fabrizio

“…The functional expression of the seven‐transmembrane domain G protein‐coupled chemokine receptor CXCR‐4/fusin in rat nerve cell was demonstrated by staining…”
Get full text

Igf1 and Pacap rescue cerebellar granule neurons from apoptosis via a common transcriptional program by Maino, B, D’Agata, V, Severini, C, Ciotti, MT, Calissano, P, Copani, A, Chang, Y-C, DeLisi, C, Cavallaro, S

“…A shift of the delicate balance between apoptosis and survival-inducing signals determines the fate of neurons during the development of the central nervous…”
Get full text

Exposure to 50 Hz electromagnetic radiation promote early maturation and differentiation in newborn rat cerebellar granule neurons by Lisi, A., Ciotti, M.T., Ledda, M., Pieri, M., Zona, C., Mercanti, D., Rieti, S., Giuliani, L., Grimaldi, S.

“…The wish of this work is the study of the effect of electromagnetic (EMF) radiations at a frequency of 50 Hz on the development of cerebellar granule neurons…”
Get full text

CXC chemokines interleukin-8 (IL-8) and growth-related gene product α (GROα) modulate Purkinje neuron activity in mouse cerebellum by Giovannelli, Aldo, Limatola, Cristina, Ragozzino, Davide, Mileo, Anna Maria, Ruggieri, Alessandro, Ciotti, Maria Teresa, Mercanti, Delio, Santoni, Angela, Eusebi, Fabrizio

“…We give here evidence that Purkinje neurons (PNs) of mouse cerebellar slices studied with patch clamp technique combined with laser confocal microscopy,…”
Get full text

Interaction of Tau with Fe65 links tau to APP by Barbato, Christian, Canu, Nadia, Zambrano, Nicola, Serafino, Annalucia, Minopoli, Giuseppina, Ciotti, Maria Teresa, Amadoro, Giuseppina, Russo, Tommaso, Calissano, Pietro

“…The β-amyloid precursor protein APP and the microtubule-associated protein Tau play a crucial role in the pathogenesis of Alzheimer's disease (AD). However,…”
Get full text

Signaling pathways activated by chemokine receptor CXCR2 and AMPA-type glutamate receptors and involvement in granule cells survival by Limatola, C, Ciotti, M.T, Mercanti, D, Santoni, A, Eusebi, F

“…We show that treatment of cerebellar granules with interleukin-8 (IL-8), growth-related gene product β (GROβ) or AMPA induced activation of PI3-K/Akt and of…”
Get full text

Glutamate Neurotoxicity in Rat Cerebellar Granule Cells: A Major Role for Xanthine Oxidase in Oxygen Radical Formation by Atlante, A., Gagliardi, S., Minervini, G. M., Ciotti, M. T., Marra, E., Calissano, P.

“…: To gain insight into the mechanism through which the neurotransmitter glutamate causally participates in several neurological diseases, in vitro cultured…”
Get full text

The Chemokine Growth-Related Gene Product β Protects Rat Cerebellar Granule Cells from Apoptotic Cell Death through α -amino-3-hydroxy-5-methyl-4-isoxazolepropionate Receptors by Limatola, Cristina, Ciotti, Maria Teresa, Mercanti, Delio, Vacca, Fabrizio, Ragozzino, Davide, Giovannelli, Aldo, Santoni, Angela, Eusebi, Fabrizio, Miledi, Ricardo

“…Cultured cerebellar granule neurons are widely used as a cellular model to study mechanisms of neuronal cell death because they undergo programmed cell death…”
Get full text