Search Results - "Cioffi, William G"

Are General Surgery Residents Ready to Practice? A Survey of the American College of Surgeons Board of Governors and Young Fellows Association by Napolitano, Lena M., MD, FACS, FCCP, FCCM, Savarise, Mark, MD, FACS, Paramo, Juan C., MD, FACS, Soot, Laurel C., MD, FACS, Todd, S. Rob, MD, FACS, Gregory, Jay, MD, FACS, Timmerman, Gary L., MD, FACS, Cioffi, William G., MD, FACS, Davis, Elisabeth, PhD, Sachdeva, Ajit K., MD, FRCSC, FACS

“…Background General surgery residency training has changed with adoption of the 80-hour work week, patient expectations, and the malpractice environment,…”
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Neutrophils from critically ill septic patients mediate profound loss of endothelial barrier integrity by Fox, Elizabeth D, Heffernan, Daithi S, Cioffi, William G, Reichner, Jonathan S

“…Sepsis is characterized by systemic immune activation and neutrophil-mediated endothelial barrier integrity compromise, contributing to end-organ dysfunction…”
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Predicting Anastomotic Leak After Elective Colectomy: Utility of a Modified Frailty Index by Dressler, Jeremy A., Shah, Nishit, Lueckel, Stephanie N., Cioffi, William G.

“…Anastomotic leak is the most dreaded complication following colonic resection. While patient frailty is increasingly being recognized as a risk factor for…”
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Integrated postoperative care model for older colorectal surgery patients improves outcomes and reduces healthcare costs by Cizginer, Sevdenur, Prohl, Eian G., Monteiro, Joao Filipe G., Yildiz, Ferhat, Jones, Richard N., Schechter, Steven, Patterson, Robert, Klipfel, Adam, Katlic, Mark Richard, Daiello, Lori A., Mujahid, Nadia, Neupane, Iva, Cioffi, William G., Ducharme, Maria, Vrees, Matthew D., McNicoll, Lynn

“…Background Older surgical patients have an increased risk for postoperative complications, driving up healthcare costs. We determined if postoperative…”
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A mentorship-based preclinical elective increases exposure, confidence, and interest in surgery by Drolet, Brian C., M.D, Sangisetty, Suma, M.D, Mulvaney, Patrick M., B.A, Ryder, Beth A., M.D., F.A.C.S, Cioffi, William G., M.D., F.A.C.S

“…Abstract Background The predicted shortage of surgeons is of growing concern with declining medical student interest in surgical careers. We hypothesized that…”
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Improved survival after induction of sepsis by cecal slurry in PD-1 knockout murine neonates by Young, Whitney A., MD, Fallon, Eleanor A., MD, Heffernan, Daithi S., MD, Efron, Philip A., MD, Cioffi, William G., MD, Ayala, Alfred, PhD

“…Background Sepsis and the ensuing immune dysfunction continue to be major contributors to neonatal morbidity and mortality. Neonatal sepsis also is associated…”
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Deep RNA sequencing of intensive care unit patients with COVID-19 by Fredericks, Alger M., Jentzsch, Maximilian S., Cioffi, William G., Cohen, Maya, Fairbrother, William G., Gandhi, Shivam J., Harrington, Elizabeth O., Nau, Gerard J., Reichner, Jonathan S., Ventetuolo, Corey E., Levy, Mitchell M., Ayala, Alfred, Monaghan, Sean F.

“…COVID-19 has impacted millions of patients across the world. Molecular testing occurring now identifies the presence of the virus at the sampling site:…”
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Predictors of 30-Day Pulmonary Complications after Outpatient Surgery: Relative Importance of Body Mass Index Weight Classifications in Risk Assessment by De Oliveira, Gildasio S., MD, MSCI, MBA, McCarthy, Robert J., PharmD, Davignon, Kristopher, MD, Chen, Herb, MD, Panaro, Heather, MD, Cioffi, William G., MD, FACS

“…Abstract Background The current literature is controversial regarding the importance of obese body mass index (BMI) classifications as a risk factor for…”
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Inhalation injury is associated with long-term employment outcomes in the burn population: Findings from a cross-sectional examination of the Burn Model System National Database by Stockly, Olivia R, Wolfe, Audrey E, Carrougher, Gretchen J, Stewart, Barclay T, Gibran, Nicole S, Wolf, Steven E, McMullen, Kara, Bamer, Alyssa M, Kowalske, Karen, Cioffi, William G, Zafonte, Ross, Schneider, Jeffrey C, Ryan, Colleen M

“…Introduction Inhalation injuries carry significant acute care burden including prolonged ventilator days and length of stay. However, few studies have examined…”
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Fas-induced Pulmonary Apoptosis and Inflammation during Indirect Acute Lung Injury by Perl, Mario, Chung, Chun-Shiang, Perl, Ulrike, Lomas-Neira, Joanne, de Paepe, Monique, Cioffi, William G, Ayala, Alfred

“…Indirect acute lung injury (ALI) is associated with high morbidity and mortality. No specific therapies have been developed, because the underlying…”
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Soluble programmed cell death receptor-1 (sPD-1): a potential biomarker with anti-inflammatory properties in human and experimental acute respiratory distress syndrome (ARDS) by Monaghan, Sean F, Chung, Chun-Shiang, Chen, Yaping, Lomas-Neira, Joanne, Fairbrother, William G, Heffernan, Daithi S, Cioffi, William G, Ayala, Alfred

“…Acute respiratory distress syndrome (ARDS) remains a common organ dysfunction in the critically ill patient. Mechanisms for its development have focused on…”
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Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness by Monaghan, Sean F, Banerjee, Debasree, Chung, Chun-Shiang, Lomas-Neira, Joanne, Cygan, Kamil J, Rhine, Christy L, Fairbrother, William G, Heffernan, Daithi S, Levy, Mitchell M, Cioffi, William G, Ayala, Alfred

“…Critically ill patients with sepsis and acute respiratory distress syndrome have severely altered physiology and immune system modifications. RNA splicing is a…”
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Decreasing the incidence of prolonged air leak after right upper lobectomy with the anterior fissureless technique by Ng, Thomas, MD, Ryder, Beth A., MD, Machan, Jason T., PhD, Cioffi, William G., MD

“…Objective For major pulmonary resections, the incidence of prolonged air leak may be highest after right upper lobectomy. Dissection through an incomplete…”
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Leukocyte-depleted blood transfusion is associated with decreased survival in resected early-stage lung cancer by Ng, Thomas, MD, Ryder, Beth A., MD, Chern, Hueylan, MD, Sellke, Frank W., MD, Machan, Jason T., PhD, Harrington, David T., MD, Cioffi, William G., MD

“…Objectives Blood transfusion has been shown to have deleterious effect on lung cancer survival, but little data are available that assess whether…”
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Identification and mechanistic basis of non-ACE2 blocking neutralizing antibodies from COVID-19 patients with deep RNA sequencing and molecular dynamics simulations by Fredericks, Alger M, East, Kyle W, Shi, Yuanjun, Liu, Jinchan, Maschietto, Federica, Ayala, Alfred, Cioffi, William G, Cohen, Maya, Fairbrother, William G, Lefort, Craig T, Nau, Gerard J, Levy, Mitchell M, Wang, Jimin, Batista, Victor S, Lisi, George P, Monaghan, Sean F

“…Variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) continue to cause disease and impair the effectiveness of treatments. The therapeutic…”
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Use of the Round Ligament of the Liver to Decrease Pancreatic Fistulas: A Novel Technique by Iannitti, David A., Coburn, Natalie G., Somberg, Joy, Ryder, Beth A., Monchik, Jack, Cioffi, William G.

“…The reported pancreatic anastomosis fistula rate for pancreaticoduodenectomy, distal pancreatectomy, or enucleation is 2% to 27%. We hypothesized that…”
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Leukadherin-1 ameliorates endothelial barrier damage mediated by neutrophils from critically ill patients by Dickinson, Catherine M, LeBlanc, Brian W, Edhi, Muhammad M, Heffernan, Daithi S, Faridi, Mohd Hafeez, Gupta, Vineet, Cioffi, William G, O'Brien, Xian, Reichner, Jonathan S

“…Multi-organ failure occurs during critical illness and is mediated in part by destructive neutrophil-to-endothelial interactions. The β2 integrin receptor, CR3…”
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Assessment of surgical residents in a vascular anastomosis laboratory by Okhah, Zachary, BA, Morrissey, Paul, MD, Harrington, David T., MD, Cioffi, William G., MD, Charpentier, Kevin P., MD

“…Abstract Background We designed a simple, low-cost workshop to teach surgical residents the basic skills of vascular anastomosis. We studied our ability to…”
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Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis by KNÖFERL, Markus W, ANGELE, Martin K, DIODATO, Michael D, SCHWACHA, Martin G, AYALA, Alfred, CIOFFI, William G, BLAND, Kirby I, CHAUDRY, Irshad H

“…To determine whether reduction of circulating female sex hormones by ovariectomy causes suppression of macrophage (Mphi) function after trauma-hemorrhage and…”
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The reflective statement: A new tool to assess resident learning by Monaghan, Sean F., MD, Blakely, Andrew M., MD, Richardson, Pamela J., C-TAGME, Miner, Thomas J., MD, Cioffi, William G., MD, Harrington, David T., MD

“…Abstract Purpose Continued assessment and redesign of the curriculum is essential for optimal surgical education. For the last 3 y, we have asked the residents…”
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