Search Results - "Cindy T J van Velthoven"

Rabies virus-based barcoded neuroanatomy resolved by single-cell RNA and in situ sequencing by Zhang, Aixin, Jin, Lei, Yao, Shenqin, Matsuyama, Makoto, van Velthoven, Cindy T J, Sullivan, Heather Anne, Sun, Na, Kellis, Manolis, Tasic, Bosiljka, Wickersham, Ian, Chen, Xiaoyin

“…Mapping the connectivity of diverse neuronal types provides the foundation for understanding the structure and function of neural circuits. High-throughput and…”
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Intranasal mesenchymal stem cell treatment for neonatal brain damage: long-term cognitive and sensorimotor improvement by Donega, Vanessa, van Velthoven, Cindy T J, Nijboer, Cora H, van Bel, Frank, Kas, Martien J H, Kavelaars, Annemieke, Heijnen, Cobi J

“…Mesenchymal stem cell (MSC) administration via the intranasal route could become an effective therapy to treat neonatal hypoxic-ischemic (HI) brain damage. We…”
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Long-term functional consequences and ongoing cerebral inflammation after subarachnoid hemorrhage in the rat by Kooijman, Elke, Nijboer, Cora H, van Velthoven, Cindy T J, Mol, Wouter, Dijkhuizen, Rick M, Kesecioglu, Jozef, Heijnen, Cobi J

“…Subarachnoid hemorrhage (SAH) represents a considerable health problem with an incidence of 6-7 per 100.000 individuals per year in Western society. We…”
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Targeting the p53 pathway to protect the neonatal ischemic brain by Nijboer, Cora H., Heijnen, Cobi J., van der Kooij, Michael A., Zijlstra, Jitske, van Velthoven, Cindy T.J., Culmsee, Carsten, van Bel, Frank, Hagberg, Henrik, Kavelaars, Annemieke

“…Objective: To investigate whether inhibition of mitochondrial p53 association using pifithrin‐μ (PFT‐μ) represents a potential novel neuroprotective strategy…”
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Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice by van Velthoven, Cindy T. J., van de Looij, Yohan, Kavelaars, Annemieke, Zijlstra, Jitske, van Bel, Frank, Huppi, Petra S., Sizonenko, Stéphane, Heijnen, Cobi J.

“…Objective: A study was undertaken to investigate the effect of neonatal hypoxic‐ischemic (HI) brain damage and mesenchymal stem cell (MSC) treatment on the…”
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GRK2: A Novel Cell-Specific Regulator of Severity and Duration of Inflammatory Pain by Eijkelkamp, Niels, Heijnen, Cobi J, Willemen, Hanneke L. D. M, Deumens, Ronald, Joosten, Elbert A. J, Kleibeuker, Wendy, den Hartog, Ilona J. M, van Velthoven, Cindy T. J, Nijboer, Cora, Nassar, Mohammed A, Dorn, Gerald W., II, Wood, John N, Kavelaars, Annemieke

“…Chronic pain associated with inflammation is a common clinical problem, and the underlying mechanisms have only begun to be unraveled. GRK2 regulates cellular…”
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Effects of antenatal glucocorticoid therapy on hippocampal histology of preterm infants by Tijsseling, Deodata, Wijnberger, Lia D E, Derks, Jan B, van Velthoven, Cindy T J, de Vries, Willem B, van Bel, Frank, Nikkels, Peter G J, Visser, Gerard H A

“…To investigate if antenatal glucocorticoid treatment has an effect on hippocampal histology of the human preterm newborn. Included were consecutive neonates…”
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Mesenchymal stem cells as a treatment for neonatal ischemic brain damage by van Velthoven, Cindy T.J., Kavelaars, Annemieke, Heijnen, Cobi J.

“…Mesenchymal stem cell (MSC)–based therapies have been proven effective in experimental models of numerous disorders. Treatment of ischemic brain injury by…”
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Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence by de Morrée, Antoine, van Velthoven, Cindy T. J., Gan, Qiang, Salvi, Jayesh S., Klein, Julian D. D., Akimenko, Igor, Quarta, Marco, Biressi, Stefano, Rando, Thomas A.

“…Tissue regeneration depends on the timely activation of adult stem cells. In skeletal muscle, the adult stem cells maintain a quiescent state and proliferate…”
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Transcriptional Profiling of Quiescent Muscle Stem Cells In Vivo by van Velthoven, Cindy T.J., de Morree, Antoine, Egner, Ingrid M., Brett, Jamie O., Rando, Thomas A.

“…Muscle stem cells (MuSCs) persist in a quiescent state and activate in response to specific stimuli. The quiescent state is both actively maintained and…”
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Mesenchymal Stem Cell Transplantation Attenuates Brain Injury After Neonatal Stroke by VELTHOVEN, Cindy T. J. Van, SHELDON, R. Ann, KAVELAARS, Annemieke, DERUGIN, Nikita, VEXLER, Zinaida S, WILLEMEN, Hanneke L. D. M, MAAS, Mirjam, HEIJNEN, Cobi J, FERRIERO, Donna M

“…Brain injury caused by stroke is a frequent cause of perinatal morbidity and mortality with limited therapeutic options. Mesenchymal stem cells (MSC) have been…”
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Enhancer viruses for combinatorial cell-subclass-specific labeling by Graybuck, Lucas T., Daigle, Tanya L., Sedeño-Cortés, Adriana E., Walker, Miranda, Kalmbach, Brian, Lenz, Garreck H., Morin, Elyse, Nguyen, Thuc Nghi, Garren, Emma, Bendrick, Jacqueline L., Kim, Tae Kyung, Zhou, Thomas, Mortrud, Marty, Yao, Shenqin, Siverts, La’ Akea, Larsen, Rachael, Gore, Bryan B., Szelenyi, Eric R., Trader, Cameron, Balaram, Pooja, van Velthoven, Cindy T.J., Chiang, Megan, Mich, John K., Dee, Nick, Goldy, Jeff, Cetin, Ali H., Smith, Kimberly, Way, Sharon W., Esposito, Luke, Yao, Zizhen, Gradinaru, Viviana, Sunkin, Susan M., Lein, Ed, Levi, Boaz P., Ting, Jonathan T., Zeng, Hongkui, Tasic, Bosiljka

“…Rapid cell type identification by new genomic single-cell analysis methods has not been met with efficient experimental access to these cell types. To…”
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Regional, Layer, and Cell-Type-Specific Connectivity of the Mouse Default Mode Network by Whitesell, Jennifer D., Liska, Adam, Coletta, Ludovico, Hirokawa, Karla E., Bohn, Phillip, Williford, Ali, Groblewski, Peter A., Graddis, Nile, Kuan, Leonard, Knox, Joseph E., Ho, Anh, Wakeman, Wayne, Nicovich, Philip R., Nguyen, Thuc Nghi, van Velthoven, Cindy T.J., Garren, Emma, Fong, Olivia, Naeemi, Maitham, Henry, Alex M., Dee, Nick, Smith, Kimberly A., Levi, Boaz, Feng, David, Ng, Lydia, Tasic, Bosiljka, Zeng, Hongkui, Mihalas, Stefan, Gozzi, Alessandro, Harris, Julie A.

“…The evolutionarily conserved default mode network (DMN) is a distributed set of brain regions coactivated during resting states that is vulnerable to brain…”
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Nasal Administration of Stem Cells: A Promising Novel Route to Treat Neonatal Ischemic Brain Damage by van Velthoven, Cindy T J, Kavelaars, Annemieke, van Bel, Frank, Heijnen, Cobi J

“…Mesenchymal stem cell (MSC) transplantation is a promising therapy to regenerate the brain after an ischemic event. We investigated the possibility to use the…”
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Mesenchymal stem cell treatment after neonatal hypoxic-ischemic brain injury improves behavioral outcome and induces neuronal and oligodendrocyte regeneration by van Velthoven, Cindy T.J, Kavelaars, Annemieke, van Bel, Frank, Heijnen, Cobi J

“…Abstract Birth asphyxia is a frequent cause of perinatal morbidity and mortality and treatment options are very limited. Our aim was to determine the effects…”
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The Endogenous Regenerative Capacity of the Damaged Newborn Brain: Boosting Neurogenesis with Mesenchymal Stem Cell Treatment by Donega, Vanessa, van Velthoven, Cindy TJ, Nijboer, Cora H, Kavelaars, Annemieke, Heijnen, Cobi J

“…Neurogenesis continues throughout adulthood. The neurogenic capacity of the brain increases after injury by, e.g., hypoxia–ischemia. However, it is well known…”
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Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain by Wang, Huijing, Heijnen, Cobi J, van Velthoven, Cindy T J, Willemen, Hanneke L D M, Ishikawa, Yoshihiro, Zhang, Xinna, Sood, Anil K, Vroon, Anne, Eijkelkamp, Niels, Kavelaars, Annemieke

“…Chronic pain is a major clinical problem, yet the mechanisms underlying the transition from acute to chronic pain remain poorly understood. In mice, reduced…”
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Osteopontin Enhances Endogenous Repair After Neonatal Hypoxic―Ischemic Brain Injury by VAN VELTHOVEN, Cindy T. J, HEIJNEN, Cobi J, VAN BEL, Frank, KAVELAARS, Annemieke

“…Hypoxic-ischemic (HI) brain injury is a frequent cause of perinatal morbidity and mortality with limited therapeutic options. To identify molecules important…”
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Mesenchymal stem cell transplantation changes the gene expression profile of the neonatal ischemic brain by van Velthoven, Cindy T.J, Kavelaars, Annemieke, van Bel, Frank, Heijnen, Cobi J

“…Highlight ► Mesenchymal stem cell induced regeneration of the ischemic brain is not due to engraftment of the cells, but related to altered gene expression of…”
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Stem Cell Quiescence: Dynamism, Restraint, and Cellular Idling by van Velthoven, Cindy T.J., Rando, Thomas A.

“…Stem cells can reside in a state of reversible growth arrest, or quiescence, for prolonged periods of time. Although quiescence has long been viewed as a…”
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