Search Results - "Cincotta, A H"

Bromocriptine: a novel approach to the treatment of type 2 diabetes by PIJL, H, OHASHI, S, DEFRONZO, R. A, MATSUDA, M, MIYAZAKI, Y, MAHANKALI, A, KUMAR, V, PIPEK, R, IOZZO, P, LANCASTER, J. L, CINCOTTA, A. H

“…Bromocriptine: a novel approach to the treatment of type 2 diabetes. H Pijl , S Ohashi , M Matsuda , Y Miyazaki , A Mahankali , V Kumar , R Pipek , P Iozzo , J…”
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Biochemical mechanisms responsible for the attenuation of diabetic and obese conditions in ob/ob mice treated with dopaminergic agonists by SCISLOWSKI, P. W. D, TOZZO, E, ZHANG, Y, PHANEUF, S, PREVELIGE, R, CINCOTTA, A. H

“…We previously reported that a two week treatment with SKF 38393 (SKF, a dopamine D1 receptor agonist), plus bromocriptine (BC, a dopamine D2 receptor agonist)…”
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Circadian peak dopaminergic activity response at the biological clock pacemaker (suprachiasmatic nucleus) area mediates the metabolic responsiveness to a high‐fat diet by Luo, S., Zhang, Y., Ezrokhi, M., Li, Y., Tsai, T.‐H., Cincotta, A. H.

“…Among vertebrate species of the major vertebrate classes in the wild, a seasonal rhythm of whole body fuel metabolism, oscillating from a lean to obese…”
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Bromocriptine (Ergoset) reduces body weight and improves glucose tolerance in obese subjects by Cincotta, A.H, Meier, A.H

“…OBJECTIVE-A double-blind placebo controlled study investigated long-term effects of Ergoset, a new quick release formulation of bromocriptine, on body weight,…”
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Increased responsiveness to the hyperglycemic, hyperglucagonemic and hyperinsulinemic effects of circulating norepinephrine in ob/ob mice by LIANG, Y, CINCOTTA, A. H

“…Several studies have implicated increased sympathetic tone as a contributing factor to the hyperglycemia and hyperglucagonemia of ob/ob mice. However, the…”
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Effects of a quick-release form of bromocriptine (Ergoset) on fasting and postprandial plasma glucose, insulin, lipid, and lipoprotein concentrations in obese nondiabetic hyperinsulinemic women by Kamath, V. (Stanford University School of Medicine, Stanford, CA.), Jones, C.N, Yip, J.C, Varasteh, B.B, Cincotta, A.H, Reaven, G.M, Chen, Y.D.I

“…Effects of a quick-release form of bromocriptine (Ergoset) on fasting and postprandial plasma glucose, insulin, lipid, and lipoprotein concentrations in obese…”
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Bromocriptine redirects metabolism and prevents seasonal onset of obese hyperinsulinemic state in Syrian hamsters by Cincotta, A.H. (Massachusetts General Hospital, Boston, MA), MacEachern, T.A, Meier, A.H

“…Bromocriptine redirects metabolism and prevents seasonal onset of the obese hyperinsulinemic state in Syrian hamsters. Metabolic and hormonal effects of…”
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Long-term infusion of norepinephrine plus serotonin into the ventromedial hypothalamus impairs pancreatic islet function by Liang, Yin, Luo, Shuqin, Cincotta, Anthony H.

“…To examine the possibility of a cause-effect relationship between enhanced monoamine content in the ventromedial hypothalamus ([VMH] a characteristic of…”
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Association of the antidiabetic effects of bromocriptine with a shift in the daily rhythm of monoamine metabolism within the suprachiasmatic nuclei of the Syrian hamster by Luo, S, Luo, J, Cincotta, A H

“…Bromocriptine, a dopamine D2 agonist, inhibits seasonal fattening and improves seasonal insulin resistance in Syrian hamsters. Alterations in daily rhythms of…”
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Suprachiasmatic nuclei monoamine metabolism of glucose tolerant versus intolerant hamsters by Luo, Shuqin, Luo, Jing, Cincotta, Anthony H

“…A critical role for temporal organization of dopaminergic and serotonergic activities within the suprachiasmatic nuclei (SCN) in the regulation of peripheral…”
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Dopaminergic neurotoxin administration to the area of the suprachiasmatic nuclei induces insulin resistance by Luo, Shuqin, Luo, Jing, Meier, Albert H, Cincotta, Anthony H

“…DOPAMINERGIC neuron neurotoxin (6-hydroxydopamine; 6-OHDA) administration directed to the hypothalamic area of the mammalian pacemaker, the suprachiasmatic…”
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Bromocriptine/SKF38393 treatment ameliorates dyslipidemia in ob/ob mice by YING ZHANG, SCISLOWSKI, P. W. D, PREVELIGE, R, PHANEUF, S, CINCOTTA, A. H

“…Our previous studies have shown that the dopaminergic D1 receptor agonist SKF38393 (SKF) plus the D2 receptor agonist bromocriptine (BC) act synergistically to…”
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Hyperinsulinemia increases norepinephrine metabolism in the ventromedial hypothalamus of rats by Cincotta, Anthony H, Luo, Shuqin, Liang, Yin

“…Numerous studies have implicated increased ventromedial hypothalamic (VMH) norepinephrine (NE) activity as a contributing factor to the obese,…”
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Bromocriptine/SKF38393 ameliorates islet dysfunction in the diabetic (db/db) mouse by Liang, Y. (Ergoscience, Charlestown, MA.), Jetton, T.L, Lubkin, M, Meier, A.H, Cincotta, A.H

“…Dysfunction of pancreatic islets plays a crucial role in the etiology of type II diabetes. Chronic hyperglycaemia or hyperlipidaemia may impair islet function…”
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Increased responsiveness of ventromedial hypothalamic neurons to norepinephrine in obese versus lean mice: relation to the metabolic syndrome by Kraszewski, K Z, Cincotta, A H

“…Studies of the effects of acute and chronic norepinephrine (NE) infusion into the ventromedial hypothalamus (VMH) of rodents indicate important roles for VMH…”
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Inhibitory effects of bromocriptine on vascular smooth muscle cell proliferation by Zhang, Ying, Cincotta, Anthony H

“…Bromocriptine (BC), an ergot alkaloid with wide therapeutic use in humans, has been shown to inhibit proliferation of several abnormally hyperproliferative…”
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Phototoxicity, redox behavior, and pharmacokinetics of benzophenoxazine analogues in EMT-6 murine sarcoma cells by CINCOTTA, L, FOLEY, J. W, CINCOTTA, A. H

“…Structural modifications to the photoinactive benzophenoxazine Nile blue A have led to three novel derivatives which include…”
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Bromocriptine inhibits the seasonally occurring obesity, hyperinsulinemia, insulin resistance, and impaired glucose tolerance in the Syrian hamster, Mesocricetus auratus by Cincotta, A H, Schiller, B C, Meier, A H

“…Seasonally obese-hyperinsulinemic female Syrian hamsters were injected daily with bromocriptine or saline for a period of 34 days to test for effects of…”
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Timed bromocriptine administration reduces body fat stores in obese subjects and hyperglycemia in type II diabetics by Meier, A H, Cincotta, A H, Lovell, W C

“…Obese postmenopausal female volunteers were given timed daily oral dosages of bromocriptine, and tested for reduction of body fat stores. This dopamine agonist…”
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Dopaminergic agonists normalize elevated hypothalamic neuropeptide Y and corticotropin-releasing hormone, body weight gain, and hyperglycemia in ob/ob mice by Bina, K G, Cincotta, A H

“…Hypothalamic neuropeptide Y (NPY) and corticotropin-releasing hormone (CRH) influence feeding and levels of plasma glucose, insulin, free fatty acids, and…”
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