Search Results - "Cimino, Ashley M"

Digital Pathology Analysis Quantifies Spatial Heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 Immune Markers in Triple-Negative Breast Cancer by Mi, Haoyang, Gong, Chang, Sulam, Jeremias, Fertig, Elana J., Szalay, Alexander S., Jaffee, Elizabeth M., Stearns, Vered, Emens, Leisha A., Cimino-Mathews, Ashley M., Popel, Aleksander S.

“…Overwhelming evidence has shown the significant role of the tumor microenvironment (TME) in governing the triple-negative breast cancer (TNBC) progression…”
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Clinical importance of high-mannose, fucosylated, and complex N-glycans in breast cancer metastasis by Ščupáková, Klára, Adelaja, Oluwatobi T, Balluff, Benjamin, Ayyappan, Vinay, Tressler, Caitlin M, Jenkinson, Nicole M, Claes, Britt Sr, Bowman, Andrew P, Cimino-Mathews, Ashley M, White, Marissa J, Argani, Pedram, Heeren, Ron Ma, Glunde, Kristine

“…Although aberrant glycosylation is recognized as a hallmark of cancer, glycosylation in clinical breast cancer (BC) metastasis has not yet been studied. While…”
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Pre-Operative Localization of Axillary Lymph Nodes with Tattoo Ink: A Preliminary Report by Myers, Kelly S, Aggarwal, Sachin, Oluyemi, Eniola T, Habibi, Mehran, Ambinder, Emily B, Azizi, Armina, Sujlana, Parvinder, Hung, Jessica, Khouri, Nagi, Eisner, David, Di Carlo, Philip A, Cimino-Mathews, Ashley M, Camp, Melissa S

“…Background: Pre-operative localization options in the axilla are limited. This study aimed to explore the utility of pre-operative localization of axillary…”
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Spatial Architecture of Single-Cell and Vasculature in Tumor Microenvironment Predicts Clinical Outcomes in Triple-Negative Breast Cancer by Mi, Haoyang, Varadhan, Ravi, Cimino-Mathews, Ashley M., Emens, Leisha A., Santa-Maria, Cesar A., Popel, Aleksander S.

“…Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited treatment options, which warrants the identification of novel…”
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Immunohistochemical Differentiation of Plasmacytoid Urothelial Carcinoma From Secondary Carcinoma Involvement of the Bladder by Borhan, Walaa M, Cimino-Mathews, Ashley M, Montgomery, Elizabeth A, Epstein, Jonathan I

“…Plasmacytoid urothelial carcinoma (UC) is a rare variant of UC that can histologically mimic metastatic cancer involving the urinary bladder. A total of 45…”
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Peripheral Nerve Sheath Tumors by Cimino-Mathews, Ashley M., MD

“…Abstract This article presents an overview of the diagnostic categories of benign and malignant nerve sheath tumors, including neuroma, neurofibroma, nerve…”
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Cancer vaccine development: protein transfer of membrane-anchored cytokines and immunostimulatory molecules by Cimino, Ashley M, Palaniswami, Purani, Kim, Andrew C, Selvaraj, Periasamy

“…Many tumor cells escape host-immune recognition by the downregulation or lack of immunostimulatory molecules. Expression of immunostimulatory molecules on…”
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Induction of anti-tumor immunity by a protein transfer mediated cancer vaccine (41.49) by Bozeman, Erica Necole, Cimino, Ashley M., Tien, Linda, Shashidnamurthy, Rangaiah, Selvaraj, Periasamy

“…The induction of a robust anti-tumor immune response is essential to the development of an effective cancer vaccine. Our lab has extensively studied a protein…”
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The role of GATA3 in breast carcinomas: a review by Asch-Kendrick, Rebecca, MD, Cimino-Mathews, Ashley, MD

“…Summary GATA3 is a zinc-binding transcription factor that regulates the differentiation of many human tissue types, including the mammary gland. In surgical…”
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PD-L1 (B7-H1) expression and the immune tumor microenvironment in primary and metastatic breast carcinomas by Cimino-Mathews, Ashley, MD, Thompson, Elizabeth, MD, PhD, Taube, Janis M., MD, Ye, Xiaobu, MD, Lu, Yao, MS, Meeker, Alan, PhD, Xu, Haiying, BS, Sharma, Rajni, PhD, Lecksell, Kristen, MS, Cornish, Toby C., MD, PhD, Cuka, Nathan, MD, Argani, Pedram, MD, Emens, Leisha A., MD

“…Summary Programmed death ligand 1 (PD-L1) expression by tumor-infiltrating lymphocytes (TILs) and tumor cells in breast cancer has been reported, but the…”
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GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas by Cimino-Mathews, Ashley, MD, Subhawong, Andrea P., MD, Illei, Peter B., MD, Sharma, Rajni, PhD, Halushka, Marc K., MD, PhD, Vang, Russell, MD, Fetting, John H., MD, Park, Ben Ho, MD, PhD, Argani, Pedram, MD

“…Summary GATA3 plays an integral role in breast luminal cell differentiation and is implicated in breast cancer progression. GATA3 immunohistochemistry is a…”
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Metastatic triple-negative breast cancers at first relapse have fewer tumor-infiltrating lymphocytes than their matched primary breast tumors: a pilot study by Cimino-Mathews, Ashley, MD, Ye, Xiaobu, MS, MD, Meeker, Alan, PhD, Argani, Pedram, MD, Emens, Leisha A., MD, PhD

“…Summary Tumor-infiltrating lymphocytes (TILs) convey clinically relevant information for primary breast cancers (PBCs). However, limited data characterizing…”
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Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas by Cimino-Mathews, Ashley, MD, Subhawong, Andrea P., MD, Elwood, Hillary, MD, Warzecha, Hind Nassar, MD, Sharma, Rajni, PhD, Park, Ben Ho, MD, PhD, Taube, Janis M., MD, Illei, Peter B., MD, Argani, Pedram, MD

“…Summary The transcription factor Sox10 mediates the differentiation of neural crest–derived cells, and Sox10 labeling by immunohistochemistry (IHC) is used…”
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Breast calcifications on mammography from systemic amyloidosis: A case report by Rossi, Joanna, Wingfield, Rebecca, Cimino-Mathews, Ashley

“…Calcifications on mammography from systemic disease at times meet diagnostic criteria for histologic sampling to exclude malignancy. We present a case of…”
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Utility of uroplakin II expression as a marker of urothelial carcinoma by Tian, Wei, MD, Guner, Gunes, MD, Miyamoto, Hiroshi, MD, PhD, Cimino-Mathews, Ashley, MD, Gonzalez-Roibon, Nilda, MD, Argani, Pedram, MD, Li, Xuan, MPH, MS, Sharma, Rajni, PhD, Subhawong, Andrea P., MD, Rezaei, Katayoon, MD, Bivalacqua, Trinity J., MD, PhD, Epstein, Jonathan I., MD, Bishop, Justin A., MD, Netto, George J., MD

“…Summary Uroplakins are markers of terminally differentiated urothelium. Uroplakin II (UPII) is a newly described sensitive marker for urothelial carcinoma…”
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A Subset of Fat-Predominant Angiomyolipomas Label for MDM2: A Potential Diagnostic Pitfall by Asch-Kendrick, Rebecca J., MD, Shetty, Shashi, PhD, Goldblum, John R., MD, Sharma, Rajni, PhD, Epstein, Jonathan I., MD, Argani, Pedram, MD, Cimino-Mathews, Ashley, MD

“…Summary Angiomyolipomas (AMLs) are typically benign mesenchymal tumors with variable histologic composition. Fat-predominant AMLs can mimic well-differentiated…”
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Androgen receptor expression is usually maintained in initial surgically resected breast cancer metastases but is often lost in end-stage metastases found at autopsy by Cimino-Mathews, Ashley, MD, Hicks, Jessica L., MS, Illei, Peter B., MD, Halushka, Marc K., MD, PhD, Fetting, John H., MD, De Marzo, Angelo M., MD, PhD, Park, Ben Ho, MD, PhD, Argani, Pedram, MD

“…Summary Androgen receptor (AR) is expressed in approximately 70% of primary breast carcinomas (PBCs) and is a promising therapeutic target for metastatic…”
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A subset of malignant phyllodes tumors harbors alterations in the Rb/p16 pathway by Cimino-Mathews, Ashley, MD, Hicks, Jessica L., MS, Sharma, Rajni, PhD, Vang, Russell, MD, Illei, Peter B., MD, De Marzo, Angelo, MD, PhD, Emens, Leisha A., MD, PhD, Argani, Pedram, MD

“…Summary Breast phyllodes tumors are fibroepithelial neoplasms with variable risk of aggressive local recurrence and distant metastasis, and the molecular…”
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Telomere length alterations unique to invasive lobular carcinoma by Heaphy, Christopher M., PhD, Asch-Kendrick, Rebecca, MD, Argani, Pedram, MD, Meeker, Alan K., PhD, Cimino-Mathews, Ashley, MD

“…Summary Telomeres are nucleoprotein complexes located at the extreme ends of eukaryotic chromosomes and protect chromosomal ends from degradation and…”
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Metastatic Disease to the Breast From Extramammary Malignancies: A Multimodality Pictorial Review by Sippo, Dorothy A., MD, MPH, Kulkarni, Kopal, MD, Carlo, Philip Di, MD, Lee, Bonmyong, MD, Eisner, David, MD, Cimino-Mathews, Ashley, MD, Harvey, Susan C., MD

“…This pictorial review demonstrates imaging features of extramammary malignancies metastatic to the breast seen with multiple modalities, including mammography,…”
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