Search Results - "Ciliberto, G."

KEAP1-driven co-mutations in lung adenocarcinoma unresponsive to immunotherapy despite high tumor mutational burden by Marinelli, D., Mazzotta, M., Scalera, S., Terrenato, I., Sperati, F., D'Ambrosio, L., Pallocca, M., Corleone, G., Krasniqi, E., Pizzuti, L., Barba, M., Carpano, S., Vici, P., Filetti, M., Giusti, R., Vecchione, A., Occhipinti, M., Gelibter, A., Botticelli, A., De Nicola, F., Ciuffreda, L., Goeman, F., Gallo, E., Visca, P., Pescarmona, E., Fanciulli, M., De Maria, R., Marchetti, P., Ciliberto, G., Maugeri-Saccà, M.

“…Immune checkpoint inhibitors (ICIs) have demonstrated significant overall survival (OS) benefit in lung adenocarcinoma (LUAD). Nevertheless, a remarkable…”
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Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015 by Galon, J, Fox, B A, Bifulco, C B, Masucci, G, Rau, T, Botti, G, Marincola, F M, Ciliberto, G, Pages, F, Ascierto, P A, Capone, M

“…The fifth "Melanoma Bridge Meeting" took place in Naples, December 1-5th, 2015. The main topics discussed at this meeting were: Molecular and Immuno advances,…”
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Immunotherapy in HER2-positive breast cancer: state of the art and future perspectives by Krasniqi, E, Barchiesi, G, Pizzuti, L, Mazzotta, M, Venuti, A, Maugeri-Saccà, M, Sanguineti, G, Massimiani, G, Sergi, D, Carpano, S, Marchetti, P, Tomao, S, Gamucci, T, De Maria, R, Tomao, F, Natoli, C, Tinari, N, Ciliberto, G, Barba, M, Vici, P

“…Breast cancer (BC) is a complex disease with primary or acquired incurability characteristics in a significant part of patients. Immunotherapeutical agents…”
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Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ by Noto, A, De Vitis, C, Pisanu, M E, Roscilli, G, Ricci, G, Catizone, A, Sorrentino, G, Chianese, G, Taglialatela-Scafati, O, Trisciuoglio, D, Del Bufalo, D, Di Martile, M, Di Napoli, A, Ruco, L, Costantini, S, Jakopin, Z, Budillon, A, Melino, G, Del Sal, G, Ciliberto, G, Mancini, R

“…Recent evidences suggest that stearoyl-CoA-desaturase 1 (SCD1), the enzyme involved in monounsaturated fatty acids synthesis, has a role in several cancers. We…”
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Rachel score: a nomogram model for predicting the prognosis of lung neuroendocrine tumors by La Salvia, A., Marcozzi, B., Manai, C., Mazzilli, R., Landi, L., Pallocca, M., Ciliberto, G., Cappuzzo, F., Faggiano, A.

“…Background Lung NET, classified in typical carcinoids (TC) and atypical carcinoids (AC), are highly heterogeneous in their biology and prognosis. The…”
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KRAS G12C mutation and risk of disease recurrence in stage I surgically resected lung adenocarcinoma by Gallina, F.T., Marinelli, D., Melis, E., Forcella, D., Taje, R., Buglioni, S., Visca, P., Torchia, A., Cecere, F.L., Botticelli, A., Santini, D., Ciliberto, G., Cappuzzo, F., Facciolo, F.

“…•It is unclear whether the KRAS G12C has a prognostic role in early stage LUAD.•In the stage I IRE cohort we found an association between KRAS G12C and worse…”
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Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells by Noto, A, Raffa, S, De Vitis, C, Roscilli, G, Malpicci, D, Coluccia, P, Di Napoli, A, Ricci, A, Giovagnoli, M R, Aurisicchio, L, Torrisi, M R, Ciliberto, G, Mancini, R

“…In recent years, studies of cancer development and recurrence have been influenced by the cancer stem cells (CSCs)/cancer-initiating cells (CICs) hypothesis…”
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Clonal KEAP1 mutations with loss of heterozygosity share reduced immunotherapy efficacy and low immune cell infiltration in lung adenocarcinoma by Scalera, S., Ricciuti, B., Mazzotta, M., Calonaci, N., Alessi, J.V., Cipriani, L., Bon, G., Messina, B., Lamberti, G., Di Federico, A., Pecci, F., Milite, S., Krasniqi, E., Barba, M., Vici, P., Vecchione, A., De Nicola, F., Ciuffreda, L., Goeman, F., Fanciulli, M., Buglioni, S., Pescarmona, E., Sharma, B., Felt, K.D., Lindsay, J., Rodig, S.J., De Maria, R., Caravagna, G., Cappuzzo, F., Ciliberto, G., Awad, M.M., Maugeri-Saccà, M.

“…KEAP1 mutations have been associated with reduced survival in lung adenocarcinoma (LUAD) patients treated with immune checkpoint inhibitors (ICIs),…”
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Gene therapy progress and prospects: transcription regulatory systems by TONIATTI, C, BUJARD, H, CORTESE, R, CILIBERTO, G

“…The clinical efficacy and safety as well as the application range of gene therapy will be broadened by developing systems capable of finely modulating the…”
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Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ by Noto, A, De Vitis, C, Pisanu, M E, Roscilli, G, Ricci, G, Catizone, A, Sorrentino, G, Chianese, G, Taglialatela-Scafati, O, Trisciuoglio, D, Del Bufalo, D, Di Martile, M, Di Napoli, A, Ruco, L, Costantini, S, Jakopin, Z, Budillon, A, Melino, G, Del Sal, G, Ciliberto, G, Mancini, R

“…This corrects the article DOI: 10.1038/onc.2017.75…”
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MicroRNA-based signatures impacting clinical course and biology of ovarian cancer: a miRNOmics study by Krasniqi, E, Sacconi, A, Marinelli, D, Pizzuti, L, Mazzotta, M, Sergi, D, Capomolla, E, Donzelli, S, Carosi, M, Bagnato, A, Gamucci, T, Tomao, S, Natoli, C, Marchetti, P, Grassadonia, A, Tinari, N, De Tursi, M, Vizza, E, Ciliberto, G, Landi, L, Cappuzzo, F, Barba, M, Blandino, G, Vici, P

“…Abstract Background In Western countries, ovarian cancer (OC) still represents the leading cause of gynecological cancer-related deaths, despite the remarkable…”
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Risk Differences Between Prediabetes And Diabetes According To Breast Cancer Molecular Subtypes by Crispo, A., Augustin, L.S.A., Grimaldi, M., Nocerino, F., Giudice, A., Cavalcanti, E., Di Bonito, M., Botti, G., De Laurentiis, M., Rinaldo, M., Esposito, E., Riccardi, G., Amore, A., Libra, M., Ciliberto, G., Jenkins, D.J.A., Montella, M.

“…Hyperglycemia and hyperinsulinemia may play a role in breast carcinogenesis and prediabetes and diabetes have been associated with increased breast cancer (BC)…”
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Decreased LRIG1 in fulvestrant-treated luminal breast cancer cells permits ErbB3 upregulation and increased growth by Morrison, M M, Williams, M M, Vaught, D B, Hicks, D, Lim, J, McKernan, C, Aurisicchio, L, Ciliberto, G, Simion, C, Sweeney, C, Cook, R S

“…ErbB3, a member of the ErbB family of receptor tyrosine kinases, is a potent activator of phosphatidyl inositol-3 kinase (PI3K) and mammalian target of…”
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Electro-gene-transfer as a new tool for cancer immunotherapy in animals by Impellizeri, J. A., Ciliberto, G., Aurisicchio, L.

“…The concept of vaccines based on the direct inoculation of plasmid DNA gained initial proof‐of‐concept in small rodent species. Further development was…”
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Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation by WANG, Z, TROILO, P. J, FOLLMER, T. T, RIZZUTO, G, CILIBERTO, G, FATTORI, E, MONICA, N. L, MANAM, S, LEDWITH, B. J, WANG, X, GRIFFITHS, T. G, PACCHIONE, S. J, BARNUM, A. B, HARPER, L. B, PAULEY, C. J, NIU, Z, DENISOVA, L

“…Plasmid vectors have been widely used for DNA vaccines and gene therapy. Following intramuscular injection, the plasmid that persists is extrachromosomal and…”
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Efficacy and safety of 5% lidocaine-medicated plasters in localized pain with neuropathic and/or inflammatory characteristics: an observational, real-world study by Amato, F, Duse, G, Consoletti, L, Lo Presti, C, Firetto, V, Ciliberto, G, Parigi, L A, Palmieri, V, Mazza, M

“…Based on clinical study results, 5% lidocaine-medicated plaster (5% LMP) is currently recommended for the treatment of localized peripheral neuropathic pain,…”
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EP-1392: The abscopal effect:efficacy of radiotherapy in patients on progression after ipilimumab 3 mg/kg by Grimaldi, A.M, Ascierto, P.A, Simeone, E, Giannarelli, D, Falivene, S, Borzillo, V, Giugliano, F, Sandomenico, F, Petrillo, A, Curvietto, M, Esposito, A, Paone, M, Palla, M, Palmieri, G, Caraco, C, Ciliberto, G, Mozzillo, N, Muto, P

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Resting echocardiography and quantitative dipyridamole technetium-99m sestamibi tomography in the identification of cardiac allograft vasculopathy and the prediction of long-term prognosis after heart transplantation by Ciliberto, G.R, Ruffini, L, Mangiavacchi, M, Parolini, M, Sara, R, Massa, D, De Maria, R, Gronda, E, Vitali, E, Parodi, O

“…Aims To evaluate the accuracy of echocardiography in conjunction with quantitative high-dose dipyridamole technetium-99m sestamibi tomography (SPECT) in…”
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Elevated levels of interleukin-6 in unstable angina by BIASUCCI, L. M, VITELLI, A, LIUZZO, G, ALTAMURA, S, CALIGIURI, G, MONACO, C, REBUZZI, A. G, CILIBERTO, G, MASERI, A

“…Elevated plasma levels of C-reactive protein have been found in the majority of patients with unstable angina. The evidence of elevated levels of acute-phase…”
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Body weight and risk of molecular breast cancer subtypes among postmenopausal Mediterranean women by Crispo, A., Montella, M., Buono, G., Grimaldi, M., D’Aiuto, M., Capasso, I., Esposito, E., Amore, A., Nocerino, F., Augustin, L.S.A., Giudice, A., Di Bonito, M., Giuliano, M., Forestieri, V., De Laurentiis, M., Rinaldo, M., Ciliberto, G., De Placido, S., Arpino, G.

“…Breast cancer (BC) is the most common malignant tumor in women, obesity is associated with increased BC incidence and mortality and high levels of circulating…”
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