Search Results - "Cihil, Kristine M."

Tgf-β1 inhibits Cftr biogenesis and prevents functional rescue of ΔF508-Cftr in primary differentiated human bronchial epithelial cells by Snodgrass, Steven M, Cihil, Kristine M, Cornuet, Pamela K, Myerburg, Michael M, Swiatecka-Urban, Agnieszka

“…CFTR is an integral transmembrane glycoprotein and a cAMP-activated Cl(-) channel. Mutations in the CFTR gene lead to Cystic Fibrosis (CF)-an autosomal…”
Get full text

The cell-based L-glutathione protection assays to study endocytosis and recycling of plasma membrane proteins by Cihil, Kristine M, Swiatecka-Urban, Agnieszka

“…Membrane trafficking involves transport of proteins from the plasma membrane to the cell interior (i.e. endocytosis) followed by trafficking to lysosomes for…”
Get full text

LMTK2-mediated Phosphorylation Regulates CFTR Endocytosis in Human Airway Epithelial Cells by Luz, Simão, Cihil, Kristine M., Brautigan, David L., Amaral, Margarida D., Farinha, Carlos M., Swiatecka-Urban, Agnieszka

“…Cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl−-selective ion channel expressed in fluid-transporting epithelia. Lemur tyrosine kinase 2…”
Get full text

Disabled-2 Protein Facilitates Assembly Polypeptide-2-independent Recruitment of Cystic Fibrosis Transmembrane Conductance Regulator to Endocytic Vesicles in Polarized Human Airway Epithelial Cells by Cihil, Kristine M., Ellinger, Philipp, Fellows, Abigail, Stolz, Donna Beer, Madden, Dean R., Swiatecka-Urban, Agnieszka

“…Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-activated Cl− channel expressed in the apical plasma membrane of fluid-transporting…”
Get full text

c-Cbl reduces stability of rescued ∆F508-CFTR in human airway epithelial cells: Implications for cystic fibrosis treatment by Cihil, Kristine M, Zimnik, Andrew, Swiatecka-Urban, Agnieszka

“…CFTR is a PKA activated Cl(-) channel expressed in the apical membrane of fluid transporting epithelia. We previously demonstrated that c-Cbl decreases CFTR…”
Get full text

Understanding the Regulation of TGF‐β1 Signaling Pathway in Human Bronchial Epithelial Cells: the Role of PP1 and LMTK2 by Cruz, Daniel F., Cihil, Kristine M., Köhn, Maja, Farinha, Carlos M., Swiatecka‐Urban, Agnieszka

“…Cystic fibrosis (CF) is a multi‐organ disease, mostly affecting the epithelial tissues in the lungs, and is caused by mutations in the Cystic Fibrosis…”
Get full text

The Cell-based L-Glutathione Protection Assays to Study Endocytosis and Recycling of Plasma Membrane Proteins by Cihil, Kristine M., Swiatecka-Urban, Agnieszka

Get full text

Tgf-[beta]1 Inhibits Cftr Biogenesis and Prevents Functional Rescue of [DELTA]F508-Cftr in Primary Differentiated Human Bronchial Epithelial Cells by Snodgrass, Steven M, Cihil, Kristine M, Cornuet, Pamela K, Myerburg, Michael M, Swiatecka-Urban, Agnieszka

“…CFTR is an integral transmembrane glycoprotein and a cAMP-activated Cl.sup.- channel. Mutations in the CFTR gene lead to Cystic Fibrosis (CF)-an autosomal…”
Get full text

c-Cbl reduces stability of rescued ∆F508-CFTR in human airway epithelial cells: Implications for cystic fibrosis treatment by Cihil, Kristine M., Zimnik, Andrew, Swiatecka-Urban, Agnieszka

“…CFTR is a PKA activated Cl - channel expressed in the apical membrane of fluid transporting epithelia. We previously demonstrated that c-Cbl decreases CFTR…”
Get full text