Search Results - "Ciganda, Martin"

Eukaryotic 5S rRNA biogenesis by Ciganda, Martin, Williams, Noreen

“…The ribosome is a large complex containing both protein and RNA which must be assembled in a precise manner to allow proper functioning in the critical role of…”
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Characterization of a novel association between two trypanosome-specific proteins and 5S rRNA by Ciganda, Martin, Williams, Noreen

“…P34 and P37 are two previously identified RNA binding proteins in the flagellate protozoan Trypanosoma brucei. RNA interference studies have determined that…”
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Comparative high-throughput analysis of the Trypanosoma cruzi response to organometallic compounds by Mosquillo, M Florencia, Smircich, Pablo, Ciganda, Martín, Lima, Analía, Gambino, Dinorah, Garat, Beatriz, Pérez-Díaz, Leticia

“…There is an urgent need to develop new drugs against Chagas' disease. In addition, the mechanisms of action of existing drugs have not been completely worked…”
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The Nuclear Export Receptors TbMex67 and TbMtr2 Are Required for Ribosome Biogenesis in Trypanosoma brucei by Rink, Constance, Ciganda, Martin, Williams, Noreen

“…Ribosomal maturation is a complex and highly conserved biological process involving migration of a continuously changing RNP across multiple cellular…”
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Trypanosoma brucei L11 Is Essential to Ribosome Biogenesis and Interacts with the Kinetoplastid-Specific Proteins P34 and P37 by Jaremko, Daniel, Ciganda, Martin, Christen, Linda, Williams, Noreen

“…Eukaryotic ribosome biogenesis is an essential cellular process involving tightly coordinated assembly of multiple rRNA and protein components. Much of our…”
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Trypanosoma brucei Homologue of Regulator of Ribosome Synthesis 1 (Rrs1) Has Direct Interactions with Essential Trypanosome-Specific Proteins by Jaremko, Daniel, Ciganda, Martin, Williams, Noreen

“…Studies in eukaryotic ribosome biogenesis have largely been performed in yeast, where they have described a highly complex process involving numerous protein…”
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A novel association between two trypanosome-specific factors and the conserved L5-5S rRNA complex by Ciganda, Martin, Prohaska, Kimberly, Hellman, Kristina, Williams, Noreen

“…P34 and P37 are two previously identified RNA binding proteins in the flagellate protozoan Trypanosoma brucei. RNA interference studies have determined that…”
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Defining the RNA-Protein Interactions in the Trypanosome Preribosomal Complex by Wang, Lei, Ciganda, Martin, Williams, Noreen

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Association of a Novel Preribosomal Complex in Trypanosoma brucei Determined by Fluorescence Resonance Energy Transfer by Wang, Lei, Ciganda, Martin, Williams, Noreen

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DNA conformational changes and cleavage by ruthenium(II) nitrofurylsemicarbazone complexes by Otero, Lucía, Smircich, Pablo, Vieites, Marisol, Ciganda, Martín, Severino, Patricia Cardoso, Terenzi, Hernán, Cerecetto, Hugo, Gambino, Dinorah, Garat, Beatriz

“…Metal complexes that establish interactions with DNA are being studied not only because of their potential use as therapeutic agents but also as tools for…”
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A novel mutation in the OAR domain of the ARX gene by Tapie, Alejandra, Pi‐Denis, Natalia, Souto, Jorge, Vomero, Alejandra, Peluffo, Gabriel, Boidi, María, Ciganda, Martín, Curbelo, Nicolás, Raggio, Victor, Roche, Leda, Pastro, Lucía

“…Key Clinical Message Mutations in ARX gene should be considered in patients with mental disability or/and epilepsy. It is an X‐linked gene that has pleiotropic…”
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Two Trypanosome-Specific Proteins Are Essential Factors for 5S rRNA Abundance and Ribosomal Assembly in Trypanosoma brucei by Hellman, Kristina M, Ciganda, Martin, Brown, Silvia V, Li, Jinlei, Ruyechan, William, Williams, Noreen

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Diversification of sphingolipid synthase activities in kinetoplastid protozoa by Ciganda, Martin, Jackson, Andrew P., Bangs, James D.

“…Phosphosphingolipids (PSL) are essential components of eukaryotic membranes. The major PSL in fungi and protists is inositol phosphorylceramide (IPC), while…”
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Ribosome biogenesis in african trypanosomes requires conserved and trypanosome-specific factors by Umaer, Khan, Ciganda, Martin, Williams, Noreen

“…Large ribosomal subunit protein L5 is responsible for the stability and trafficking of 5S rRNA to the site of eukaryotic ribosomal assembly. In Trypanosoma…”
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Translational control by Trypanosoma brucei DRBD18 contributes to the maintenance of the procyclic state by Ciganda, Martin, Sotelo-Silveira, José, Dubey, Ashutosh P, Pandey, Parul, Smith, Joseph T, Shen, Shichen, Qu, Jun, Smircich, Pablo, Read, Laurie K

“…occupies distinct niches throughout its life cycle, within both the mammalian and tsetse fly hosts. The immunological and biochemical complexity and…”
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Selective nuclear export of mRNAs is promoted by DRBD18 in Trypanosoma brucei by Mishra, Amartya, Kaur, Jan Naseer, McSkimming, Daniel I., Hegedűsová, Eva, Dubey, Ashutosh P., Ciganda, Martin, Paris, Zdeněk, Read, Laurie K.

“…Kinetoplastids, including Trypanosoma brucei, control gene expression primarily at the posttranscriptional level. Nuclear mRNA export is an important, but…”
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Ribosome biogenesis requires a highly diverged XRN family 5'->3' exoribonuclease for rRNA processing in Trypanosoma brucei by Sakyiama, Joseph, Zimmer, Sara L, Ciganda, Martin, Williams, Noreen, Read, Laurie K

“…Although biogenesis of ribosomes is a crucial process in all organisms and is thus well conserved, Trypanosoma brucei ribosome biogenesis, of which maturation…”
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Analysis of a novel pre-ribosomal complex in Trypanosoma brucei by Ciganda, Martin

“…Trypanosoma brucei is the causative agent of human African trypanosomiasis. It belongs to the kinetoplastids, a group of early-branching eukaryotes with many…”
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A novel type of single-stranded nucleic acid binding protein recognizing a highly frequent motif in the intergenic regions of Trypanosoma cruzi by Duhagon, Marı́a Ana, Dallagiovanna, Bruno, Ciganda, Martı́n, Ruyechan, William, Williams, Noreen, Garat, Beatriz

“…Regulation of gene expression in trypanosomatids is not yet well understood. Genes are organized in long polycistronic transcriptional units separated by…”
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Analysis of a novel pre-ribosomal complex in Trypanosoma brucei by Ciganda, Martin

“…Trypanosoma brucei is the causative agent of human African trypanosomiasis. It belongs to the kinetoplastids, a group of early-branching eukaryotes with many…”
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