Search Results - "Cifdaloz, Metehan"

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors by Karras, Panagiotis, Riveiro-Falkenbach, Erica, Cañón, Estela, Tejedo, Cristina, Calvo, Tonantzin G., Martínez-Herranz, Raúl, Alonso-Curbelo, Direna, Cifdaloz, Metehan, Perez-Guijarro, Eva, Gómez-López, Gonzalo, Ximenez-Embun, Pilar, Muñoz, Javier, Megias, Diego, Olmeda, David, Moscat, Jorge, Ortiz-Romero, Pablo L., Rodríguez-Peralto, Jose L., Soengas, María S.

“…Modulators of mRNA stability are not well understood in melanoma, an aggressive tumor with complex changes in the transcriptome. Here we report the ability of…”
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Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers by Pérez-Guijarro, Eva, Karras, Panagiotis, Cifdaloz, Metehan, Martínez-Herranz, Raúl, Cañón, Estela, Graña, Osvaldo, Horcajada-Reales, Celia, Alonso-Curbelo, Direna, Calvo, Tonantzin G., Gómez-López, Gonzalo, Bellora, Nicolas, Riveiro-Falkenbach, Erica, Ortiz-Romero, Pablo L., Rodríguez-Peralto, José L., Maestre, Lorena, Roncador, Giovanna, de Agustín Asensio, Juan C., Goding, Colin R., Eyras, Eduardo, Megías, Diego, Méndez, Raúl, Soengas, María S.

“…Nuclear 3’-end-polyadenylation is essential for the transport, stability and translation of virtually all eukaryotic mRNAs. Poly(A) tail extension can also…”
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Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1 by Cifdaloz, Metehan, Osterloh, Lisa, Graña, Osvaldo, Riveiro-Falkenbach, Erica, Ximénez-Embún, Pilar, Muñoz, Javier, Tejedo, Cristina, Calvo, Tonantzin G., Karras, Panagiotis, Olmeda, David, Miñana, Belén, Gómez-López, Gonzalo, Cañon, Estela, Eyras, Eduardo, Guo, Haihong, Kappes, Ferdinand, Ortiz-Romero, Pablo L., Rodríguez-Peralto, Jose L., Megías, Diego, Valcárcel, Juan, Soengas, María S.

“…Melanomas are well-known for their altered mRNA expression profiles. Yet, the specific contribution of mRNA binding proteins (mRBPs) to melanoma development…”
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Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine by Olmeda, David, Cerezo-Wallis, Daniela, Riveiro-Falkenbach, Erica, Pennacchi, Paula C., Contreras-Alcalde, Marta, Ibarz, Nuria, Cifdaloz, Metehan, Catena, Xavier, Calvo, Tonantzin G., Cañón, Estela, Alonso-Curbelo, Direna, Suarez, Javier, Osterloh, Lisa, Graña, Osvaldo, Mulero, Francisca, Megías, Diego, Cañamero, Marta, Martínez-Torrecuadrada, Jorge L., Mondal, Chandrani, Di Martino, Julie, Lora, David, Martinez-Corral, Inés, Bravo-Cordero, J. Javier, Muñoz, Javier, Puig, Susana, Ortiz-Romero, Pablo, Rodriguez-Peralto, José L., Ortega, Sagrario, Soengas, María S.

“…Genetically engineered ‘lymphoreporter’ mouse strains are used to track melanoma dissemination in vivo , identifying midkine as a tumour-secreted factor that…”
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RAB7 Controls Melanoma Progression by Exploiting a Lineage-Specific Wiring of the Endolysosomal Pathway by Alonso-Curbelo, Direna, Riveiro-Falkenbach, Erica, Pérez-Guijarro, Eva, Cifdaloz, Metehan, Karras, Panagiotis, Osterloh, Lisa, Megías, Diego, Cañón, Estela, Calvo, Tonantzin G., Olmeda, David, Gómez-López, Gonzalo, Graña, Osvaldo, Sánchez-Arévalo Lobo, Víctor Javier, Pisano, David G., Wang, Hao-Wei, Ortiz-Romero, Pablo, Tormo, Damià, Hoek, Keith, Rodríguez-Peralto, José L., Joyce, Johanna A., Soengas, María S.

“…Although common cancer hallmarks are well established, lineage-restricted oncogenes remain less understood. Here, we report an inherent dependency of melanoma…”
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Metastatic risk and resistance to BRAF inhibitors in melanoma defined by selective allelic loss of ATG5 by García-Fernández, María, Karras, Panagiotis, Checinska, Agnieszka, Cañón, Estela, Calvo, Guadalupe T., Gómez-López, Gonzalo, Cifdaloz, Metehan, Colmenar, Angel, Espinosa-Hevia, Luis, Olmeda, David, Soengas, María S.

“…Melanoma is a paradigm of aggressive tumors with a complex and heterogeneous genetic background. Still, melanoma cells frequently retain developmental traits…”
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DEK oncogene is overexpressed during melanoma progression by Riveiro‐Falkenbach, Erica, Ruano, Yolanda, García‐Martín, Rosa M., Lora, David, Cifdaloz, Metehan, Acquadro, Francesco, Ballestín, Claudio, Ortiz‐Romero, Pablo L., Soengas, María S., Rodríguez‐Peralto, José L.

“…Summary DEK is an oncoprotein involved in a variety of cellular functions, such as DNA repair, replication, and transcriptional control. DEK is preferentially…”
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Whole body imaging of lymphovascular niches identifies premetastatic roles of MIDKINE by Olmeda, David, Cerezo-Wallis, Daniela, Riveiro-Falkenbach, Erica, Pennacchi, Paula C., Contreras-Alcalde, Marta, Ibarz, Nuria, Cifdaloz, Metehan, Catena, Xavier, Calvo, Tonantzin G., Cañón, Estela, Alonso, Direna, Suarez, Javier, Osterloh, Lisa, Graña, Osvaldo, Mulero, Francisca, Megías, Diego, Cañamero, Marta, Martínez-Torrecuadrada, Jorge, Mondal, Chandrani, Di Martino, Julie, Lora, David, Martinez-Corral, Inés, Bravo-Cordero, J. Javier, Muñoz, Javier, Puig, Susana, Ortiz-Romero, Pablo, Rodriguez-Peralto, José L, Ortega, Sagrario, Soengas, María S.

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