Search Results - "Cid‐Díaz, Tania"

Obestatin signalling counteracts glucocorticoid‐induced skeletal muscle atrophy via NEDD4/KLF15 axis by Cid‐Díaz, Tania, Leal‐López, Saúl, Fernández‐Barreiro, Fátima, González‐Sánchez, Jessica, Santos‐Zas, Icía, Andrade‐Bulos, Luis J., Rodríguez‐Fuentes, Manuel E., Mosteiro, Carlos S., Mouly, Vincent, Casabiell, Xesús, Relova, Jose Luis, Pazos, Yolanda, Camiña, Jesus P.

“…Background A therapeutic approach for the treatment of glucocorticoid‐induced skeletal muscle atrophy should be based on the knowledge of the molecular…”
Get full text

Obestatin controls the ubiquitin–proteasome and autophagy–lysosome systems in glucocorticoid‐induced muscle cell atrophy by Cid‐Díaz, Tania, Santos‐Zas, Icía, González‐Sánchez, Jessica, Gurriarán‐Rodríguez, Uxía, Mosteiro, Carlos S., Casabiell, Xesús, García‐Caballero, Tomás, Mouly, Vincent, Pazos, Yolanda, Camiña, Jesús P.

“…Background Many pathological states characterized by muscle atrophy are associated with an increase in circulating glucocorticoids and poor patient prognosis,…”
Get full text

Improvement of Duchenne muscular dystrophy phenotype following obestatin treatment by González‐Sánchez, Jessica, Sánchez‐Temprano, Agustín, Cid‐Díaz, Tania, Pabst‐Fernández, Regina, Mosteiro, Carlos S., Gallego, Rosalía, Nogueiras, Ruben, Casabiell, Xesús, Butler‐Browne, Gillian S., Mouly, Vincent, Relova, José Luis, Pazos, Yolanda, Camiña, Jesús P.

“…Background This study was performed to test the therapeutic potential of obestatin, an autocrine anabolic factor regulating skeletal muscle repair, to…”
Get full text

β-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells by Santos-Zas, Icía, Gurriarán-Rodríguez, Uxía, Cid-Díaz, Tania, Figueroa, Gabriela, González-Sánchez, Jessica, Bouzo-Lorenzo, Mónica, Mosteiro, Carlos S, Señarís, José, Casanueva, Felipe F, Casabiell, Xesús, Gallego, Rosalía, Pazos, Yolanda, Mouly, Vincent, Camiña, Jesús P

“…Obestatin/GPR39 signaling stimulates skeletal muscle repair by inducing the expansion of satellite stem cells as well as myofiber hypertrophy. Here, we…”
Get full text

Obestatin controls skeletal muscle fiber-type determination by Santos-Zas, Icía, Cid-Díaz, Tania, González-Sánchez, Jessica, Gurriarán-Rodriguez, Uxía, Seoane-Mosteiro, Carlos, Porteiro, Begoña, Nogueiras, Rubén, Casabiell, Xesús, Relova, José Luis, Gallego, Rosalía, Mouly, Vincent, Pazos, Yolanda, Camiña, Jesus P.

“…Obestatin/GPR39 signaling stimulates skeletal muscle growth and repair by inducing both G-protein-dependent and -independent mechanisms linking the activated…”
Get full text

Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis by Muta, Yu, Linares, Juan F., Martinez-Ordoñez, Anxo, Duran, Angeles, Cid-Diaz, Tania, Kinoshita, Hiroto, Zhang, Xiao, Han, Qixiu, Nakanishi, Yuki, Nakanishi, Naoko, Cordes, Thekla, Arora, Gurpreet K., Ruiz-Martinez, Marc, Reina-Campos, Miguel, Kasashima, Hiroaki, Yashiro, Masakazu, Maeda, Kiyoshi, Albaladejo-Gonzalez, Ana, Torres-Moreno, Daniel, García-Solano, José, Conesa-Zamora, Pablo, Inghirami, Giorgio, Metallo, Christian M., Osborne, Timothy F., Diaz-Meco, Maria T., Moscat, Jorge

“…The metabolic and signaling pathways regulating aggressive mesenchymal colorectal cancer (CRC) initiation and progression through the serrated route are…”
Get full text

Whole-mount staining of mouse colorectal cancer organoids and fibroblast-organoid co-cultures by Martinez-Ordoñez, Anxo, Cid-Diaz, Tania, Duran, Angeles, Han, Qixiu, Moscat, Jorge, Diaz-Meco, Maria T.

“…Imaging organoid culture provides an excellent tool for studying complex diseases such as cancer. However, retaining the morphology of intact organoids for…”
Get full text

Protocol to characterize mouse intestinal epithelial cell lineage using Opal multiplex immunofluorescence by Martinez-Ordoñez, Anxo, Kinoshita, Hiroto, Cid-Diaz, Tania, Duran, Angeles, Osrodek, Marta, Diaz-Meco, Maria T., Moscat, Jorge

“…Applying Opal multiplex immunofluorescence (OMI) to characterize intestinal tissues of genetically engineered mouse models provides an excellent tool for…”
Get full text

Mouse model of colorectal cancer: Orthotopic co-implantation of tumor and stroma cells in cecum and rectum by Kasashima, Hiroaki, Duran, Angeles, Cid-Diaz, Tania, Muta, Yu, Kinoshita, Hiroto, Batlle, Eduard, Diaz-Meco, Maria T., Moscat, Jorge

“…In vivo interrogation of the functional role of genes implicated in colorectal cancer (CRC) is limited by the need for physiological models that mimic the…”
Get full text

Air-liquid organotypic assays to investigate cellular crosstalk in the tumor microenvironment of cancer cells by Cid-Diaz, Tania, Lodeiro, Andrea C., Duran, Angeles, Moscat, Jorge, Diaz-Meco, Maria T.

“…Air-liquid organotypic culture models enable the study of the cellular crosstalk in the tumor microenvironment. This 3D assay recapitulates the tumor niche…”
Get full text

An Orthotopic Implantation Mouse Model of Hepatocellular Carcinoma with Underlying Liver Steatosis by Kasashima, Hiroaki, Duran, Angeles, Cid-Diaz, Tania, Kudo, Yotaro, Diaz-Meco, Maria T., Moscat, Jorge

“…This protocol provides the steps required for a mouse liver orthotopic implantation model. The reliable pre-clinical animal models that have similar…”
Get full text

Publisher Correction: Obestatin controls skeletal muscle fiber-type determination by Santos-Zas, Icía, Cid-Díaz, Tania, González-Sánchez, Jessica, Gurriarán-Rodriguez, Uxía, Seoane-Mosteiro, Carlos, Porteiro, Begoña, Nogueiras, Rubén, Casabiell, Xesús, Relova, José Luis, Gallego, Rosalía, Mouly, Vincent, Pazos, Yolanda, Camiña, Jesus P.

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
Get full text

[beta]-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells by Santos-zas, Icía, Gurriarán-rodríguez, Uxía, Cid-díaz, Tania, Figueroa, Gabriela, González-sánchez, Jessica, Bouzo-lorenzo, Mónica, Mosteiro, Carlos S, Señarís, José, Casanueva, Felipe F, Casabiell, Xesús, Gallego, Rosalía, Pazos, Yolanda, Mouly, Vincent, Camiña, Jesús P

“…Obestatin/GPR39 signaling stimulates skeletal muscle repair by inducing the expansion of satellite stem cells as well as myofiber hypertrophy. Here, we…”
Get full text

Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer by Martinez-Ordoñez, Anxo, Duran, Angeles, Ruiz-Martinez, Marc, Cid-Diaz, Tania, Zhang, Xiao, Han, Qixiu, Kinoshita, Hiroto, Muta, Yu, Linares, Juan F., Kasashima, Hiroaki, Nakanishi, Yuki, Omar, Mohamed, Nishimura, Sadaaki, Avila, Leandro, Yashiro, Masakazu, Maeda, Kiyoshi, Pannellini, Tania, Pigazzi, Alessio, Inghirami, Giorgio, Marchionni, Luigi, Sigal, Darren, Diaz-Meco, Maria T., Moscat, Jorge

“…Mesenchymal colorectal cancer (mCRC) is microsatellite stable (MSS), highly desmoplastic, with CD8+ T cells excluded to the stromal periphery, resistant to…”
Get full text

The lactate-NAD + axis activates cancer-associated fibroblasts by downregulating p62 by Linares, Juan F, Cid-Diaz, Tania, Duran, Angeles, Osrodek, Marta, Martinez-Ordoñez, Anxo, Reina-Campos, Miguel, Kuo, Hui-Hsuan, Elemento, Olivier, Martin, M Laura, Cordes, Thekla, Thompson, Timothy C, Metallo, Christian M, Moscat, Jorge, Diaz-Meco, Maria T

“…Reduced p62 levels are associated with the induction of the cancer-associated fibroblast (CAF) phenotype, which promotes tumorigenesis in vitro and in vivo…”
Get full text

Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a therapeutic vulnerability in mesenchymal colorectal cancer by Martinez-Ordoñez, Anxo, Duran, Angeles, Ruiz-Martinez, Marc, Cid-Diaz, Tania, Zhang, Xiao, Han, Qixiu, Kinoshita, Hiroto, Muta, Yu, Linares, Juan F., Kasashima, Hiroaki, Nakanishi, Yuki, Omar, Mohamed, Nishimura, Sadaaki, Avila, Leandro, Yashiro, Masakazu, Maeda, Kiyoshi, Pannellini, Tania, Pigazzi, Alessio, Inghirami, Giorgio, Marchionni, Luigi, Sigal, Darren, Diaz-Meco, Maria T., Moscat, Jorge

“…Mesenchymal colorectal cancer (mCRC) is microsatellite stable (MSS), highly desmoplastic, with CD8 + T cells excluded to the stromal periphery, resistant to…”
Get full text