Preoperative Risk Factors for Periprosthetic Joint Infection: A Narrative Review of the Literature

Preoperative Risk Factors for Periprosthetic Joint Infection: A Narrative Review of the Literature

Periprosthetic joint infection (PJI) poses a challenging complication for many patients undergoing arthroplasty, and the literature identifies numerous risk factors. A comprehensive understanding of the primary risk and protective factors for PJI is valuable for surgeons. This article aims to compil...

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Bibliographic Details
Published in:Healthcare (Basel) Vol. 12; no. 6; p. 666
Main Authors: Lucenti, Ludovico, Testa, Gianluca, Caldaci, Alessia, Sammartino, Fabio, Cicio, Calogero, Ilardo, Martina, Sapienza, Marco, Pavone, Vito
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 01-03-2024
MDPI
Subjects:
Antibiotics
Arthritis
arthroplasty
Artificial joints
Asymptomatic
Complications and side effects
Diabetes
Glucose
Infection
infections
Joint surgery
Mortality
Patients
periprosthetic joint infection
PJI
replacement
Review
Risk factors
Substance abuse treatment
Urinary tract diseases
Urinary tract infections
Urine
Urogenital system
Vitamin deficiency
Italy
risk factors
arthroplasty
infections
periprosthetic joint infection
replacement
PJI
prevention
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Summary:Periprosthetic joint infection (PJI) poses a challenging complication for many patients undergoing arthroplasty, and the literature identifies numerous risk factors. A comprehensive understanding of the primary risk and protective factors for PJI is valuable for surgeons. This article aims to compile and summarize the key risk factors for PJI documented in the literature. Some risk factors are related to the nutritional status of patients, with obesity, weight loss, hypovitaminosis, and malnutrition being frequently reported. Pathologies affecting patients also contribute to PJI risk, including septic arthritis, hepatitis, diabetes, urinary tract infections, anemia, hypothyroidism, osteoporosis, and dental pathologies. Unhealthy habits, such as tobacco and drug abuse, are significant factors. Previous corticosteroid injections may also play a role in infection development. A few protective factors are also reported in the literature (use of statins, preoperative decolonization, and preadmission skin preparation). The identification of risk factors and the implementation of evidence-based preoperative protocols are essential steps in reducing the incidence of PJI.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:2227-9032
2227-9032
DOI:10.3390/healthcare12060666