Search Results - "Cibelli, Jose B."

Functional characterization of CDX2 during bovine preimplantation development in vitro by Goissis, Marcelo D., Cibelli, Jose B.

“…SUMMARY Placental defects are common in bovine embryos produced using assisted reproductive techniques. A proper understanding of the events leading to inner…”
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Histone chaperone ASF1A is required for maintenance of pluripotency and cellular reprogramming by Gonzalez-Muñoz, Elena, Arboleda-Estudillo, Yohanna, Otu, Hasan H., Cibelli, Jose B.

“…Unfertilized oocytes have the intrinsic capacity to remodel sperm and the nuclei of somatic cells. The discoveries that cells can change their phenotype from…”
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Human Somatic Cell Nuclear Transfer Is Alive and Well by Cibelli, Jose B.

“…In this issue, Chung et al. (2014) generate human embryonic stem cells by fusing an adult somatic cell to a previously enucleated human oocyte, in agreement…”
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Jumonji domain-containing protein 3 regulates histone 3 lysine 27 methylation during bovine preimplantation development by Canovas, Sebastian, Cibelli, Jose B, Ross, Pablo J

“…Understanding the mechanisms of epigenetic remodeling that follow fertilization is a fundamental step toward understanding the bases of early embryonic…”
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Mitochondrial rejuvenation after induced pluripotency by Suhr, Steven T, Chang, Eun Ah, Tjong, Jonathan, Alcasid, Nathan, Perkins, Guy A, Goissis, Marcelo D, Ellisman, Mark H, Perez, Gloria I, Cibelli, Jose B

“…As stem cells of the early embryo mature and differentiate into all tissues, the mitochondrial complement undergoes dramatic functional improvement…”
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Comparative analysis of single-cell transcriptomics in human and Zebrafish oocytes by Can, Handan, Chanumolu, Sree K, Gonzalez-Muñoz, Elena, Prukudom, Sukumal, Otu, Hasan H, Cibelli, Jose B

“…Zebrafish is a popular model organism, which is widely used in developmental biology research. Despite its general use, the direct comparison of the zebrafish…”
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Interspecies nuclear transfer: implications for embryonic stem cell biology by Beyhan, Zeki, Iager, Amy E, Cibelli, Jose B

“…Accessibility of human oocytes for research poses a serious ethical challenge to society. This fact categorically holds true when pursuing some of the most…”
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Identification of a novel gene set in human cumulus cells predictive of an oocyte's pregnancy potential by Iager, Amy E., M.Sc, Kocabas, Arif M., Ph.D, Otu, Hasan H., Ph.D, Ruppel, Patricia, Ph.D, Langerveld, Anna, Ph.D, Schnarr, Patricia, B.Sc, Suarez, Mariluz, M.Sc, Jarrett, John C., M.D, Conaghan, Joe, Ph.D, Rosa, Guilherme J.M., Ph.D, Fernández, Emilio, M.D, Rawlins, Richard G., Ph.D, Cibelli, Jose B., D.V.M., Ph.D, Crosby, Javier A., Ph.D

“…Objective To identify a gene expression signature in human cumulus cells (CCs) predictive of pregnancy outcome across multiple clinics, taking into account the…”
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Quantitative proteomics reveals the dynamic proteome landscape of zebrafish embryos during the maternal-to-zygotic transition by Fang, Fei, Chen, Daoyang, Basharat, Abdul Rehman, Poulos, William, Wang, Qianyi, Cibelli, Jose B., Liu, Xiaowen, Sun, Liangliang

“…Maternal-to-zygotic transition (MZT) is central to early embryogenesis. However, its underlying molecular mechanisms are still not well described. Here, we…”
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Telomere dynamics in human cells reprogrammed to pluripotency by Suhr, Steven T, Chang, Eun Ah, Rodriguez, Ramon M, Wang, Kai, Ross, Pablo J, Beyhan, Zeki, Murthy, Shashanka, Cibelli, Jose B

“…Human induced pluripotent stem cells (IPSCs) have enormous potential in the development of cellular models of human disease and represent a potential source of…”
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Evidence of a Pluripotent Human Embryonic Stem Cell Line Derived from a Cloned Blastocyst by Hwang, Woo Suk, Ryu, Young June, Park, Jong Hyuk, Park, Eul Soon, Lee, Eu Gene, Koo, Ja Min, Jeon, Hyun Yong, Lee, Byeong Chun, Kang, Sung Keun, Kim, Sun Jong, Ahn, Curie, Hwang, Jung Hye, Park, Ky Young, Cibelli, Jose B., Moon, Shin Yong

“…Somatic cell nuclear transfer (SCNT) technology has recently been used to generate animals with a common genetic composition. In this study, we report the…”
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Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells by Suárez-Alvarez, Beatriz, Rodriguez, Ramón M, Calvanese, Vincenzo, Blanco-Gelaz, Miguel A, Suhr, Steve T, Ortega, Francisco, Otero, Jesus, Cibelli, Jose B, Moore, Harry, Fraga, Mario F, López-Larrea, Carlos

“…Human embryonic stem cells (hESCs) are an attractive resource for new therapeutic approaches that involve tissue regeneration. hESCs have exhibited low…”
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Generation of leukemia inhibitory factor and basic fibroblast growth factor-dependent induced pluripotent stem cells from canine adult somatic cells by Luo, Jiesi, Suhr, Steven T, Chang, Eun Ah, Wang, Kai, Ross, Pablo J, Nelson, Laura L, Venta, Patrick J, Knott, Jason G, Cibelli, Jose B

“…For more than thirty years, the dog has been used as a model for human diseases. Despite efforts made to develop canine embryonic stem cells, success has been…”
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Reprogrammed transcriptome in rhesus-bovine interspecies somatic cell nuclear transfer embryos by Wang, Kai, Otu, Hasan H, Chen, Ying, Lee, Young, Latham, Keith, Cibelli, Jose B

“…Global activation of the embryonic genome (EGA), one of the most critical steps in early mammalian embryo development, is recognized as the time when…”
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Functional Characterization of SOX2 in Bovine Preimplantation Embryos1 by Goissis, Marcelo D, Cibelli, Jose B

“…To date, efforts to establish pluripotent embryonic stem cells from bovine embryos have failed. The lack of reliable pluripotency markers is an important…”
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Polycomb gene expression and histone H3 lysine 27 trimethylation changes during bovine preimplantation development by Ross, Pablo J, Ragina, Neli P, Rodriguez, Ramon M, Iager, Amy E, Siripattarapravat, Kannika, Lopez-Corrales, Nestor, Cibelli, Jose B

“…Trimethylation of histone H3 at lysine 27 (H3K27me3) is established by polycomb group genes and is associated with stable and heritable gene silencing. The aim…”
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Chemotherapy-induced late transgenerational effects in mice by Kujjo, Loro L, Chang, Eun A, Pereira, Ricardo J G, Dhar, Shilpa, Marrero-Rosado, Brenda, Sengupta, Satyaki, Wang, Hongbing, Cibelli, Jose B, Perez, Gloria I

“…To our knowledge, there is no report on long-term reproductive and developmental side effects in the offspring of mothers treated with a widely used…”
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Cloned transgenic calves produced from nonquiescent fetal fibroblasts by Cibelli, J.B. (University of Massachusetts, Amherst, MA.), Stice, S.L, Golueke, P.J, Kane, J.J, Jerry, J, Blackwell, C, Ponce de Leon, F.A, Robl, J.M

“…An efficient system for genetic modification and large-scale cloning of cattle is of importance for agriculture, biotechnology, and human medicine. Here,…”
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Parthenogenetic Stem Cells in Nonhuman Primates by Cibelli, Jose B., Grant, Kathleen A., Chapman, Karen B., Cunniff, Kerrianne, Worst, Travis, Green, Heather L., Walker, Stephen J., Gutin, Philip H., Vilner, Lucy, Tabar, Viviane, Dominko, Tanja, Kane, Jeff, Wettstein, Peter J., Lanza, Robert P., Studer, Lorenz, Vrana, Kent E., West, Michael D.

“…Cibelli et al demonstrate in a study broad differentiation capabilities of primate pluripotent stem cells derived by parthenogenesis. After in vitro maturation…”
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Extension of Cell Life-Span and Telomere Length in Animals Cloned from Senescent Somatic Cells by Lanza, Robert P., Cibelli, Jose B., Blackwell, Catherine, Cristofalo, Vincent J., Francis, Mary Kay, Baerlocher, Gabriela M., Mak, Jennifer, Schertzer, Michael, Chavez, Elizabeth A., Sawyer, Nancy, Lansdorp, Peter M., West, Michael D.

“…The potential of cloning depends in part on whether the procedure can reverse cellular aging and restore somatic cells to a phenotypically youthful state…”
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