Search Results - "Ciaudo, Constance"

Non-canonical functions of the microprocessor by Ciaudo, Constance

“…Constance Ciaudo tells us about two articles that changed her perception of microRNA biogenesis proteins…”
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Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair by Savic, Natasa, Ringnalda, Femke Cas, Lindsay, Helen, Berk, Christian, Bargsten, Katja, Li, Yizhou, Neri, Dario, Robinson, Mark D, Ciaudo, Constance, Hall, Jonathan, Jinek, Martin, Schwank, Gerald

“…The CRISPR-Cas9 targeted nuclease technology allows the insertion of genetic modifications with single base-pair precision. The preference of mammalian cells…”
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Argonaute Proteins: From Structure to Function in Development and Pathological Cell Fate Determination by Müller, Madlen, Fazi, Francesco, Ciaudo, Constance

“…The highly conserved Argonaute protein family members play a central role in the regulation of gene expression networks, orchestrating the establishment and…”
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Comparative analysis of differential gene expression tools for RNA sequencing time course data by Spies, Daniel, Renz, Peter F, Beyer, Tobias A, Ciaudo, Constance

“…Abstract RNA sequencing (RNA-seq) has become a standard procedure to investigate transcriptional changes between conditions and is routinely used in research…”
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Dynamics in Transcriptomics: Advancements in RNA-seq Time Course and Downstream Analysis by Spies, Daniel, Ciaudo, Constance

“…Analysis of gene expression has contributed to a plethora of biological and medical research studies. Microarrays have been intensively used for the profiling…”
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Prediction of the miRNA interactome – Established methods and upcoming perspectives by Schäfer, Moritz, Ciaudo, Constance

“…MicroRNAs (miRNAs) are well-studied small noncoding RNAs involved in post-transcriptional gene regulation in a wide range of organisms, including mammals…”
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LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation by Chow, Jennifer C., Ciaudo, Constance, Fazzari, Melissa J., Mise, Nathan, Servant, Nicolas, Glass, Jacob L., Attreed, Matthew, Avner, Philip, Wutz, Anton, Barillot, Emmanuel, Greally, John M., Voinnet, Olivier, Heard, Edith

“…During X chromosome inactivation (XCI), Xist RNA coats and silences one of the two X chromosomes in female cells. Little is known about how XCI spreads across…”
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Role for RNAi in the Selective Correction of DNA Methylation Defects by Teixeira, Felipe Karam, Heredia, Fabiana, Sarazin, Alexis, Roudier, François, Boccara, Martine, Ciaudo, Constance, Cruaud, Corinne, Poulain, Julie, Berdasco, Maria, Fraga, Mario F, Voinnet, Olivier, Wincker, Patrick, Esteller, Manel, Colot, Vincent

“…DNA methylation is essential for silencing transposable elements and some genes in higher eukaryotes, which suggests that this modification must be tightly…”
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Naive and primed murine pluripotent stem cells have distinct miRNA expression profiles by Jouneau, Alice, Ciaudo, Constance, Sismeiro, Odile, Brochard, Vincent, Jouneau, Luc, Vandormael-Pournin, Sandrine, Coppée, Jean-Yves, Zhou, Qi, Heard, Edith, Antoniewski, Christophe, Cohen-Tannoudji, Michel

“…Over the last years, the microRNA (miRNA) pathway has emerged as a key component of the regulatory network of pluripotency. Although clearly distinct states of…”
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The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation by Duszczyk, Malgorzata M., Wischnewski, Harry, Kazeeva, Tamara, Arora, Rajika, Loughlin, Fionna E., von Schroetter, Christine, Pradère, Ugo, Hall, Jonathan, Ciaudo, Constance, Allain, Frédéric H.-T.

“…Dead End (DND1) is an RNA-binding protein essential for germline development through its role in post-transcriptional gene regulation. The molecular mechanisms…”
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Argonaute 2 Is Required for Extra-embryonic Endoderm Differentiation of Mouse Embryonic Stem Cells by Ngondo, Richard Patryk, Cirera-Salinas, Daniel, Yu, Jian, Wischnewski, Harry, Bodak, Maxime, Vandormael-Pournin, Sandrine, Geiselmann, Anna, Wettstein, Rahel, Luitz, Janina, Cohen-Tannoudji, Michel, Ciaudo, Constance

“…In mouse, although four Argonaute (AGO) proteins with partly overlapping functions in small-RNA pathways exist, only Ago2 deficiency causes embryonic…”
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ncPRO-seq: a tool for annotation and profiling of ncRNAs in sRNA-seq data by CHEN, Chong-Jian, SERVANT, Nicolas, CIAUDO, Constance, BARILLOT, Emmanuel, TOEDLING, Joern, SARAZIN, Alexis, MARCHAIS, Antonin, DUVERNOIS-BERTHET, Evelyne, COGNAT, Valérie, COLOT, Vincent, VOINNET, Olivier, HEARD, Edith

“…Non-coding RNA (ncRNA) PROfiling in small RNA (sRNA)-seq (ncPRO-seq) is a stand-alone, comprehensive and flexible ncRNA analysis pipeline. It can interrogate…”
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Fast In Vitro Procedure to Identify Extraembryonic Differentiation Defect of Mouse Embryonic Stem Cells by Ngondo, Richard Patryk, Cohen-Tannoudji, Michel, Ciaudo, Constance

“…Mouse embryonic stem cells (mESCs) are a powerful model to study early mouse development. These blastocyst-derived cells can maintain pluripotency and…”
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Regulation of LINE-1 Elements by miR-128 Is Not Conserved in Mouse Embryonic Stem Cells by Bodak, Maxime, Yu, Jian, Ciaudo, Constance

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Editorial: The RNA Revolution in Embryonic Development and Cell Differentiation in Health and Disease by Rosa, Alessandro, Ciaudo, Constance, Sumazin, Pavel, Fazi, Francesco

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RNAi-dependent and independent control of LINE1 accumulation and mobility in mouse embryonic stem cells by Ciaudo, Constance, Jay, Florence, Okamoto, Ikuhiro, Chen, Chong-Jian, Sarazin, Alexis, Servant, Nicolas, Barillot, Emmanuel, Heard, Edith, Voinnet, Olivier

“…In most mouse tissues, long-interspersed elements-1 (L1s) are silenced via methylation of their 5'-untranslated regions (5'-UTR). A gradual loss-of-methylation…”
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Tsix transcription across the Xist gene alters chromatin conformation without affecting Xist transcription: implications for X-chromosome inactivation by Navarro, Pablo, Pichard, Sylvain, Ciaudo, Constance, Avner, Philip, Rougeulle, Claire

“…X-chromosome inactivation (XCI) is highly dynamic during early mouse embryogenesis and strictly depends on the Xist noncoding RNA. The regulation of Xist and…”
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Exit from Pluripotency Assay of Mouse Embryonic Stem Cells by Cirera-Salinas, Daniel, Ciaudo, Constance

“…A novel method to assess the dissolution of the core pluripotency transcription-factor circuit of mouse Embryonic Stem Cells (mESCs) has been developed ( Ying…”
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Regulation of LINE-1 in mammals by Bodak Maxime, Yu Jian, Ciaudo Constance

“…Transposable elements (TEs) are mobile DNA elements that represent almost half of the human genome. Transposition of TEs has been implicated as a source of…”
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Inhibition of FGF and TGF-β Pathways in hESCs Identify STOX2 as a Novel SMAD2/4 Cofactor by Renz, Peter F, Spies, Daniel, Tsikrika, Panagiota, Wutz, Anton, Beyer, Tobias A, Ciaudo, Constance

“…The fibroblast growth factor (FGF) and the transforming growth factor-β (TGF-β) pathways are both involved in the maintenance of human embryonic stem cells…”
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