Search Results - "Ciaravino, Elizabeth J."

Abstract 725: Protein kinase-CK2 inhibition as a potential treatment for multiple myeloma by Turner, Joel G., Dawson, Jana L., Ciaravino, Elizabeth J., Koomen, John M., Sullivan, Daniel M.

“…Hypothesis Nuclear export of topo IIα to the cytoplasm results in de novo resistance to topo IIα inhibitors in hematological malignancies. Background We have…”
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Blocking a Topoisomerase IIα Nuclear Export Signal Sensitizes Human Multiple Myeloma Cells to Topoisomerase II Inhibitors by Turner, Joel G., Rowe, Thomas C., Ostrov, David A., Ciaravino, Elizabeth J., Gump, Jana L., Sullivan, Daniel M.

“…Abstract 2850 Poster Board II-826 We have previously demonstrated that topoisomerase IIa (topo IIa) is exported from the nucleus of high density human multiple…”
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Intrinsic Drug Resistance in Multiple Myeloma to Doxorubicin Is Mediated by Soluble Factors by Sullivan, Daniel, Dawson, Jana L., Ciaravino, Elizabeth J., Turner, Joel G.

“…Drug resistance continues to be a major obstacle in the treatment of multiple myeloma. Data have shown that the bone marrow microenvironment plays an important…”
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