Search Results - "Cialfi, Samantha"

Synergistic post-transcriptional regulation of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) by miR-101 and miR-494 specific binding by Megiorni, Francesca, Cialfi, Samantha, Dominici, Carlo, Quattrucci, Serena, Pizzuti, Antonio

“…microRNAs (miRNAs) are a class of regulatory small non-coding molecules that control gene expression at post-transcriptional level. Deregulation of miRNA…”
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MicroRNAs as Modulators of the Immune Response in T-Cell Acute Lymphoblastic Leukemia by Del Gaizo, Martina, Sergio, Ilaria, Lazzari, Sara, Cialfi, Samantha, Pelullo, Maria, Screpanti, Isabella, Felli, Maria Pia

“…Acute lymphoblastic leukaemia (ALL) is an aggressive haematological tumour driven by the malignant transformation and expansion of B-cell (B-ALL) or T-cell…”
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DNA Damage Stress: Cui Prodest? by Verma, Nagendra, Franchitto, Matteo, Zonfrilli, Azzurra, Cialfi, Samantha, Palermo, Rocco, Talora, Claudio

“…DNA is an entity shielded by mechanisms that maintain genomic stability and are essential for living cells; however, DNA is constantly subject to assaults from…”
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PLK1 targets NOTCH1 during DNA damage and mitotic progression by De Blasio, Carlo, Zonfrilli, Azzurra, Franchitto, Matteo, Mariano, Germano, Cialfi, Samantha, Verma, Nagendra, Checquolo, Saula, Bellavia, Diana, Palermo, Rocco, Benelli, Dario, Screpanti, Isabella, Talora, Claudio

“…Notch signaling plays a complex role in carcinogenesis, and its signaling pathway has both tumor suppressor and oncogenic components. To identify regulators…”
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Yeast-Based Screen to Identify Natural Compounds with a Potential Therapeutic Effect in Hailey-Hailey Disease by Ficociello, Graziella, Zonfrilli, Azzurra, Cialfi, Samantha, Talora, Claudio, Uccelletti, Daniela

“…The term orthodisease defines human disorders in which the pathogenic gene has orthologs in model organism genomes. Yeasts have been instrumental for gaining…”
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Deep Sequencing the microRNA profile in rhabdomyosarcoma reveals down-regulation of miR-378 family members by Megiorni, Francesca, Cialfi, Samantha, McDowell, Heather P, Felsani, Armando, Camero, Simona, Guffanti, Alessandro, Pizer, Barry, Clerico, Anna, De Grazia, Alessandra, Pizzuti, Antonio, Moles, Anna, Dominici, Carlo

“…Rhabdomyosarcoma (RMS) is a highly malignant tumour accounting for nearly half of soft tissue sarcomas in children. MicroRNAs (miRNAs) represent a class of…”
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Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL by Pelullo, Maria, Quaranta, Roberta, Talora, Claudio, Checquolo, Saula, Cialfi, Samantha, Felli, Maria Pia, te Kronnie, Geertruy, Borga, Chiara, Besharat, Zein Mersini, Palermo, Rocco, Di Marcotullio, Lucia, Capobianco, Anthony J, Gulino, Alberto, Screpanti, Isabella, Bellavia, Diana

“…Abstract Deregulated Notch signaling has been extensively linked to T-cell acute lymphoblastic leukemia (T-ALL). Here, we show a direct relationship between…”
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5FU/Oxaliplatin-Induced Jagged1 Cleavage Counteracts Apoptosis Induction in Colorectal Cancer: A Novel Mechanism of Intrinsic Drug Resistance by Pelullo, Maria, Zema, Sabrina, De Carolis, Mariangela, Cialfi, Samantha, Giuli, Maria Valeria, Palermo, Rocco, Capalbo, Carlo, Giannini, Giuseppe, Screpanti, Isabella, Checquolo, Saula, Bellavia, Diana

“…Colorectal cancer (CRC) is characterized by early metastasis, resistance to anti-cancer therapy, and high mortality rate. Despite considerable progress in the…”
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The translation factor eIF6 is a Notch-dependent regulator of cell migration and invasion by Benelli, Dario, Cialfi, Samantha, Pinzaglia, Michela, Talora, Claudio, Londei, Paola

“…A growing body of evidence indicates that protein factors controlling translation play an important role in tumorigenesis. The protein known as eIF6 is a…”
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The epigenetic factor BORIS/CTCFL regulates the NOTCH3 gene expression in cancer cells by Zampieri, Michele, Ciccarone, Fabio, Palermo, Rocco, Cialfi, Samantha, Passananti, Claudio, Chiaretti, Sabina, Nocchia, Daniela, Talora, Claudio, Screpanti, Isabella, Caiafa, Paola

“…Aberrant upregulation of NOTCH3 gene plays a critical role in cancer pathogenesis. However, the underlying mechanisms are still unknown. We tested here the…”
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Intracellular NADPH Levels Affect the Oligomeric State of the Glucose 6-Phosphate Dehydrogenase by Saliola, Michele, Tramonti, Angela, Lanini, Claudio, Cialfi, Samantha, De Biase, Daniela, Falcone, Claudio

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Functional cooperation between ASK1 and p21Waf1/Cip1 in the balance of cell-cycle arrest, cell death and tumorigenesis of stressed keratinocytes by De Blasio, Carlo, Verma, Nagendra, Moretti, Marta, Cialfi, Samantha, Zonfrilli, Azzurra, Franchitto, Matteo, Truglio, Federica, De Smaele, Enrico, Ichijo, Hidenori, Naguro, Isao, Screpanti, Isabella, Talora, Claudio

“…Both CDKN1A (p21 Waf1/Cip1 ) and Apoptosis signal-regulating kinase 1 (ASK1) play important roles in tumorigenesis. The role of p21 Waf1/Cip1 in attenuating…”
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The p53 Codon 72 Pro/Pro Genotype Identifies Poor-Prognosis Neuroblastoma Patients: Correlation with Reduced Apoptosis and Enhanced Senescence by the p53-72P Isoform by Cattelani, Sara, Ferrari-Amorotti, Giovanna, Galavotti, Sara, Defferrari, Raffaella, Tanno, Barbara, Cialfi, Samantha, Vergalli, Jenny, Fragliasso, Valentina, Guerzoni, Clara, Manzotti, Gloria, Rachele Soliera, Angela, Menin, Chiara, Bertorelle, Roberta, McDowell, Heather P, Inserra, Alessandro, Belli, Maria Luisa, Varesio, Luigi, Tweddle, Deborah, Tonini, Gian Paolo, Altavista, Pierluigi, Dominici, Carlo, Raschellà, Giuseppe, Calabretta, Bruno

“…Abstract The p53 gene is rarely mutated in neuroblastoma, but codon 72 polymorphism that modulates its proapoptotic activity might influence cancer risk and…”
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Hypotonic, Acidic Oxidizing Solution Containing Hypochlorous Acid (HClO) as a Potential Treatment of Hailey-Hailey Disease by Cialfi, Samantha, Calabro, Salvatore, Franchitto, Matteo, Zonfrilli, Azzurra, Screpanti, Isabella, Talora, Claudio

“…Hailey-Hailey disease (HHD) is a rare, chronic and recurrent blistering disorder, characterized by erosions occurring primarily in intertriginous regions and…”
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Novel TONSL variants cause SPONASTRIME dysplasia and associate with spontaneous chromosome breaks, defective cell proliferation and apoptosis by Micale, Lucia, Cialfi, Samantha, Fusco, Carmela, Cinque, Luigia, Castellana, Stefano, Biagini, Tommaso, Talora, Claudio, Notarangelo, Angelantonio, Bisceglia, Luigi, Taruscio, Domenica, Salvatore, Marco, Castori, Marco

“…Abstract SPONASTRIME dysplasia is an ultrarare spondyloepimetaphyseal dysplasia featuring short stature and short limbs, platyspondyly, depressed nasal bridge…”
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miR-125b/NRF2/HO-1 axis is involved in protection against oxidative stress of cystic fibrosis: A pilot study by Pelullo, Maria, Savi, Daniela, Quattrucci, Serena, Cimino, Giuseppe, Pizzuti, Antonio, Screpanti, Isabella, Talora, Claudio, Cialfi, Samantha

“…In the physiopathology of cystic fibrosis (CF), oxidative stress implications are recognized and widely accepted. The cystic fibrosis transmembrane conductance…”
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Elevated levels of miR-145 correlate with SMAD3 down-regulation in Cystic Fibrosis patients by Megiorni, Francesca, Cialfi, Samantha, Cimino, Giuseppe, De Biase, Riccardo Valerio, Dominici, Carlo, Quattrucci, Serena, Pizzuti, Antonio

“…Abstract MicroRNAs (miRNAs) have recently emerged as important gene regulators in Cystic Fibrosis (CF), a common monogenic disease characterized by severe…”
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Loss of ATP2C1 function promotes trafficking and degradation of NOTCH1: Implications for Hailey‐Hailey disease by Zonfrilli, Azzurra, Truglio, Federica, Simeone, Alessandra, Pelullo, Maria, De Turris, Valeria, Benelli, Dario, Checquolo, Saula, Bellavia, Diana, Palermo, Rocco, Uccelletti, Daniela, Screpanti, Isabella, Cialfi, Samantha, Talora, Claudio

“…Hailey‐Hailey disease (HHD) is a rare autosomal dominantly inherited disorder caused by mutations in the ATP2C1 gene that encodes an adenosine triphosphate…”
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In vitro toxicity studies of zinc oxide nano- and microrods on mammalian cells: A comparative analysis by Zanni, Elena, De Palma, Silvia, Chandraiahgari, Chandrakanth Reddy, De Bellis, Giovanni, Cialfi, Samantha, Talora, Claudio, Palleschi, Claudio, Sarto, Maria Sabrina, Uccelletti, Daniela, Mancini, Patrizia

“…This study aims at investigating the cytotoxicity of zinc oxide nanorods (ZnO-NR) and microrods (ZnO-MR) in two different human cell lines. The materials were…”
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The loss of ATP2C1 impairs the DNA damage response and induces altered skin homeostasis: Consequences for epidermal biology in Hailey-Hailey disease by Cialfi, Samantha, Le Pera, Loredana, De Blasio, Carlo, Mariano, Germano, Palermo, Rocco, Zonfrilli, Azzurra, Uccelletti, Daniela, Palleschi, Claudio, Biolcati, Gianfranco, Barbieri, Luca, Screpanti, Isabella, Talora, Claudio

“…Mutation of the Golgi Ca 2+ -ATPase ATP2C1 is associated with deregulated calcium homeostasis and altered skin function. ATP2C1 mutations have been identified…”
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