Search Results - "Ci, Shusheng"

DNA polymerase beta modulates cancer progression via enhancing CDH13 expression by promoter demethylation by Wang, Meina, Long, Kaili, Li, Enjie, Li, Lulu, Li, Binghua, Ci, Shusheng, He, Lingfeng, Pan, Feiyan, Hu, Zhigang, Guo, Zhigang

“…DNA polymerase β (Pol β) plays a critical role in DNA base excision repair (BER), which is involved in maintaining genomic stability and in the modulation of…”
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Correction: DNA polymerase beta modulates cancer progression via enhancing CDH13 expression by promoter demethylation by Wang, Meina, Long, Kaili, Li, Enjie, Li, Lulu, Li, Binghua, Ci, Shusheng, He, Lingfeng, Pan, Feiyan, Hu, Zhigang, Guo, Zhigang

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Excessive iron inhibits insulin secretion via perturbing transcriptional regulation of SYT7 by OGG1 by Zhao, Xingqi, Ma, Ying, Shi, Munan, Huang, Miaoling, Xin, Jingyu, Ci, Shusheng, Chen, Meimei, Jiang, Tao, Hu, Zhigang, He, Lingfeng, Pan, Feiyan, Guo, Zhigang

“…Although iron overload is closely related to the occurrence of type 2 diabetes mellitus (T2DM), the specific mechanism is unclear. Here, we found that…”
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β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages by Li, Daqi, Zhang, Qian, Li, Lu, Chen, Kexin, Yang, Junlei, Dixit, Deobrat, Gimple, Ryan C, Ci, Shusheng, Lu, Chenfei, Hu, Lang, Gao, Jiancheng, Shan, Danyang, Li, Yangqing, Zhang, Junxia, Shi, Zhumei, Gu, Danling, Yuan, Wei, Wu, Qiulian, Yang, Kailin, Zhao, Linjie, Qiu, Zhixin, Lv, Deguan, Gao, Wei, Yang, Hui, Lin, Fan, Wang, Qianghu, Man, Jianghong, Li, Chaojun, Tao, Weiwei, Agnihotri, Sameer, Qian, Xu, Shi, Yu, You, Yongping, Zhang, Nu, Rich, Jeremy N, Wang, Xiuxing

“…Glioblastoma (GBM) is a complex ecosystem that includes a heterogeneous tumor population and the tumor-immune microenvironment (TIME), prominently containing…”
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Arginine methylation of APE1 promotes its mitochondrial translocation to protect cells from oxidative damage by Zhang, Yilan, Zhang, Qi, Li, LuLu, Mu, Dan, Hua, Ke, Ci, Shusheng, Shen, Lei, Zheng, Li, Shen, Binghui, Guo, Zhigang

“…Apurinic/apyrimidinic endonuclease 1 (APE1) is an essential multifunctional protein in mammals that plays critical roles in DNA repair and redox signaling…”
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Src‐mediated phosphorylation of GAPDH regulates its nuclear localization and cellular response to DNA damage by Ci, Shusheng, Xia, Wen, Liang, Weichu, Qin, Lihong, Zhang, Yilan, Dianov, Grigory L., Wang, Meina, Zhao, Xingqi, Wu, Congye, Alagamuthu, Karthick Kumar, Hu, Zhigang, He, Lingfeng, Pan, Feiyan, Guo, Zhigang

“…Glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) is a key enzyme involved in energy metabolism. Recently, GAPDH has been suggested to have extraglycolytic…”
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GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1‐dependent manner by Shi, Munan, Hou, Jiajia, Liang, Weichu, Li, Qianwen, Shao, Shan, Ci, Shusheng, Shu, Chuanjun, Zhao, Xingqi, Zhao, Shanmeizi, Huang, Miaoling, Wu, Congye, Hu, Zhigang, He, Lingfeng, Guo, Zhigang, Pan, Feiyan

“…Homologous recombination (HR), a form of error‐free DNA double‐strand break (DSB) repair, is important for the maintenance of genomic integrity. Here, we…”
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Targeting nuclear pore complex and therapeutic response in glioblastoma stem cells by Yang, Kailin, Ci, Shusheng, Zhang, Junxia, Lu, Chenfei, Zhang, Qian, Wu, Qiulian, Hu, Lang, Gao, Jiancheng, Li, Daqi, Shan, Danyang, Li, Yangqing, Li, Lu, Zhao, Linjie, Agnihotri, Sameer, Qian, Xu, Shi, Yu, Zhang, Nu, You, Yongping, Wang, Xiuxing, Rich, Jeremy N.

“…e14000 Background: Glioblastoma is the most prevalent and lethal primary intrinsic tumor in the central nervous system. Glioblastoma stem cells (GSCs)…”
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Dual Role of CXCL8 in Maintaining the Mesenchymal State of Glioblastoma Stem Cells and M2-Like Tumor-Associated Macrophages by Yuan, Wei, Zhang, Qian, Gu, Danling, Lu, Chenfei, Dixit, Deobrat, Gimple, Ryan C, Gao, Yisu, Gao, Jiancheng, Li, Daqi, Shan, Danyang, Hu, Lang, Li, Lu, Li, Yangqing, Ci, Shusheng, You, Hao, Yan, Linping, Chen, Kexin, Zhao, Ningwei, Xu, Chuanhai, Lan, Jianyun, Liu, Dong, Zhang, Junxia, Shi, Zhumei, Wu, Qiulian, Yang, Kailin, Zhao, Linjie, Qiu, Zhixin, Lv, Deguan, Gao, Wei, Yang, Hui, Lin, Fan, Wang, Qianghu, Man, Jianghong, Li, Chaojun, Tao, Weiwei, Agnihotri, Sameer, Qian, Xu, Mack, Stephen C, Zhang, Nu, You, Yongping, Rich, Jeremy N, Sun, Guan, Wang, Xiuxing

“…The dynamic interplay between glioblastoma stem cells (GSC) and tumor-associated macrophages (TAM) sculpts the tumor immune microenvironment (TIME) and…”
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Inhibition of AKT Sensitizes Cancer Cells to Antineoplastic Drugs by Downregulating Flap Endonuclease 1 by Zhu, Hong, Wu, Congye, Wu, Ting, Xia, Wen, Ci, Shusheng, He, Weiru, Zhang, Yilan, Li, Lulu, Zhou, Shiying, Zhang, Jing, Edick, Ashlin M, Zhang, Anna, Pan, Fei-Yan, Hu, Zhigang, He, Lingfeng, Guo, Zhigang

“…DNA repair mechanisms are crucial for cell survival. It increases the cancer cell's ability to resist DNA damage. FEN1 is involved in DNA replication and…”
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Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake by Gu, Danling, Zhou, Fengqi, You, Hao, Gao, Jiancheng, Kang, Tao, Dixit, Deobrat, Wu, Qiulian, Yang, Kailin, Ci, Shusheng, Shan, Danyang, Fan, Xiao, Yuan, Wei, Zhang, Qian, Lu, Chenfei, Li, Daqi, Zhao, Ningwei, Shi, Zhumei, Gao, Wei, Lin, Fan, Man, Jianghong, Wang, Qianghu, Qian, Xu, Mack, Stephen C, Tao, Weiwei, Agnihotri, Sameer, Zhang, Nu, You, Yongping, Rich, Jeremy N, Zhang, Junxia, Wang, Xiuxing

“…Abstract Background Glioblastomas (GBMs) display striking dysregulation of metabolism to promote tumor growth. Glioblastoma stem cells (GSCs) adapt to regions…”
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Two‐way crosstalk between BER and c‐NHEJ repair pathway is mediated by Pol‐β and Ku70 by Xia, Wen, Ci, Shusheng, Li, Menghan, Wang, Meina, Dianov, Grigory L., Ma, Zhuang, Li, Lulu, Hua, Ke, Alagamuthu, Karthick Kumar, Qing, Lihong, Luo, Libo, Edick, Ashlin M., Liu, Lingjie, Hu, Zhigang, He, Lingfeng, Pan, Feiyan, Guo, Zhigang

“…Multiple DNA repair pathways may be involved in the removal of the same DNA lesion caused by endogenous or exogenous agents. Although distinct DNA repair…”
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