Search Results - "Chvatchko, Yolande"

Expression of interleukin-18 in human atherosclerotic plaques and relation to plaque instability by MALLAT, Ziad, CORBAZ, Anne, SCOAZEC, Alexandra, BESNARD, Sandrine, LESECHE, Guy, CHVATCHKO, Yolande, TEDGUI, Alain

“…Interleukin (IL)-18 is a potent proinflammatory cytokine with potential atherogenic properties. Its expression and role in atherosclerosis, however, are…”
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p38 Mitogen-activated protein kinase downregulates endothelial progenitor cells by SEEGER, Florian H, HAENDELER, Judith, DIMMELER, Stefanie, WALTER, Dirk H, ROCHWALSKY, Ulrich, REINHOLD, Johannes, URBICH, Carmen, RÖSSIG, Lothar, CORBAZ, Anne, CHVATCHKO, Yolande, ZEIHER, Andreas M

“…Transplantation of endothelial progenitor cells (EPCs) improves neovascularization after ischemia, but patients with coronary artery disease (CAD) or diabetes…”
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Interleukin-18/Interleukin-18 Binding Protein Signaling Modulates Atherosclerotic Lesion Development and Stability by Mallat, Ziad, Corbaz, Anne, Scoazec, Alexandra, Graber, Pierre, Alouani, Sami, Esposito, Bruno, Humbert, Yves, Chvatchko, Yolande, Tedgui, Alain

“…ABSTRACT—Interleukin (IL)-18 is the interferon-γ–inducing factor and has other proinflammatory properties. The precise role of IL-18 in immunoinflammatory…”
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Evidence for altered interleukin (IL)‐18 pathway in human heart failure by Mallat, Ziad, Heymes, Christophe, Corbaz, Anne, Logeart, Damien, Alouani, Sami, Cohen‐Solal, Alain, Seidler, Tim, Hasenfuss, Gerd, Chvatchko, Yolande, Shah, Ajay M., Tedgui, Alain

“…ABSTRACT Interleukin (IL)‐18 is the interferon‐γ‐inducing factor and has potent proinflammatory activities. IL‐18 has been recently implicated in…”
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Erratum to: Protective effect of TSLP delivered at the gut mucosa level by recombinant lactic acid bacteria in DSS-induced colitis mouse model by Aubry, Camille, Michon, Christophe, Chain, Florian, Chvatchko, Yolande, Goffin, Laurence, Zimmerli, Simone C, Leguin, Sylvia, Langella, Philippe, Bermudez-Humaran, Luis, Chatel, Jean-Marc

“…After publication of the original article [1] it was brought to our attention that author Yolande Chvatchko was incorrectly included as Yolande Chvatchenko…”
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Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis by Plater-Zyberk, C, Joosten, L A, Helsen, M M, Sattonnet-Roche, P, Siegfried, C, Alouani, S, van De Loo, F A, Graber, P, Aloni, S, Cirillo, R, Lubberts, E, Dinarello, C A, van Den Berg, W B, Chvatchko, Y

“…Two distinct IL-18 neutralizing strategies, i.e. a rabbit polyclonal anti-mouse IL-18 IgG and a recombinant human IL-18 binding protein (rhIL-18BP), were used…”
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A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock by Chvatchko, Y, Hoogewerf, A J, Meyer, A, Alouani, S, Juillard, P, Buser, R, Conquet, F, Proudfoot, A E, Wells, T N, Power, C A

“…CC chemokine receptor (CCR)4, a high affinity receptor for the CC chemokines thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine…”
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A NOVEL IL-18BP ELISA SHOWS ELEVATED SERUM IL-18BP IN SEPSIS AND EXTENSIVE DECREASE OF FREE IL-18 by Novick, Daniela, Schwartsburd, Boris, Pinkus, Ron, Suissa, Dan, Belzer, Ilana, Sthoeger, Zev, Keane, William F., Chvatchko, Yolande, Kim, Soo-Hyun, Fantuzzi, Giamila, Dinarello, Charles A., Rubinstein, Menachem

“…IL-18 binding protein (IL-18BP) is a circulating antagonist of the proinflammatory Th1 cytokine IL-18. It effectively blocks IL-18 by forming a 1:1 high…”
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IL-18-Binding Protein Expression by Endothelial Cells and Macrophages Is Up-Regulated During Active Crohn's Disease by Corbaz, Anne, ten Hove, Tessa, Herren, Suzanne, Graber, Pierre, Schwartsburd, Boris, Belzer, Ilana, Harrison, Jillian, Plitz, Thomas, Kosco-Vilbois, Marie H, Kim, Soo-Hyun, Dinarello, Charles A, Novick, Daniela, van Deventer, Sander, Chvatchko, Yolande

“…The pathogenesis of Crohn's disease (CD) remains under intense investigation. Increasing evidence suggests a role for mature IL-18 in the induction of…”
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Germinal center formation and local immunoglobulin E (IgE) production in the lung after an airway antigenic challenge by Chvatchko, Y, Kosco-Vilbois, M H, Herren, S, Lefort, J, Bonnefoy, J Y

“…Airway inflammation plays a central role in the pathogenesis of asthma. However, the precise contribution of all cell types in the development and maintenance…”
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Interleukin-18/Interleukin-18 Binding Protein Signaling Modulates Ischemia-Induced Neovascularization in Mice Hindlimb by Mallat, Ziad, Silvestre, Jean-Sébastien, Le Ricousse-Roussanne, Sophie, Lecomte-Raclet, Laurence, Corbaz, Anne, Clergue, Michel, Duriez, Micheline, Barateau, Véronique, Akira, Shizuo, Tedgui, Alain, Tobelem, Gérard, Chvatchko, Yolande, Lévy, Bernard I

“…ABSTRACT—Identification of factors that may stimulate ischemia-induced neovascularization without increasing atherosclerotic plaque progression is of major…”
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962 CALY-002, AN ANTI-IL-15 ANTIBODY, RESULTS IN HISTOLOGICAL AND CLINICAL IMPROVEMENT IN PATIENTS WITH EOSINOPHILIC ESOPHAGITIS IN A PHASE 1A/B STUDY by Bredenoord, Arjan, Houbiers, Jos G., Vanuytsel, Tim, Chvatchko, Yolande, Hoff, Dag Arne, Conchillo, José M., Dellon, Evan S., Tran, Isabelle, Guyon-Gellin, Nicolas, Holz, Josefin-Beate, Vicari, Alain

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The physiology of murine germinal center reactions by Kosco-Vilbois, Marie H., Bonnefoy, Jean-Yves, Chvatchko, Yolande

“…Germinal center responses are the mechanism that the immune system uses normally to generate high affinity antigen‐specific B‐cell receptors and secreted…”
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1021 INTERIM RESULTS FROM A FIRST-IN-HUMAN STUDY OF THE ANTI-IL-15 ANTIBODY CALY-002 FOR TREATING CELIAC DISEASE AND EOSINOPHILIC ESOPHAGITIS by Houbiers, Jos G., Chvatchko, Yolande, Mäki, Markku, Lundin, Knut E., Schuppan, Detlef, Bredenoord, Arjan, Schumann, Michael, Bouma, Gerd, Tran, Isabelle, Guyon-Gellin, Nicolas, Holz, Josefin-Beate, Vicari, Alain

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Anti-MMP-9 Antibody: A Promising Therapeutic Strategy for Treatment of Inflammatory Bowel Disease Complications with Fibrosis by Goffin, Laurence, Fagagnini, Stefania, Vicari, Alain, Mamie, Céline, Melhem, Hassan, Weder, Bruce, Lutz, Christian, Lang, Silvia, Scharl, Michael, Rogler, Gerhard, Chvatchko, Yolande, Hausmann, Martin

“…Despite medical treatments or surgical options, more than one-third of patients with Crohn's disease suffer from recurring fistulae. Matrix metalloprotease 9…”
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789 CALY-002, AN ANTI-IL-15 ANTIBODY, PREVENTS GLUTEN CHALLENGEINDUCED MUCOSAL DAMAGE AND INFLAMMATION: RESULTS FROM A PHASE 1A/B STUDY by Schumann, Michael, Houbiers, Jos G., Chvatchko, Yolande, Mäki, Markku, Lundin, Knut E., Schuppan, Detlef, Vanuytsel, Tim, Zopf, Yurdagül, Deprez, Pierre H., Hasselblatt, Peter, Taavela, Juha, Hoff, Dag Arne, Wahab, Peter, Isola, Jorma, Tran, Isabelle, Guyon-Gellin, Nicolas, Holz, Josefin-Beate, Vicari, Alain, Bouma, Gerd

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IL-18-independent cytotoxic T lymphocyte activation and IFN-gamma production during experimental acute graft-versus-host disease by Arnold, Diana, Wasem, Christoph, Juillard, Pierre, Graber, Pierre, Cima, Igor, Frutschi, Corina, Herren, Simon, Jakob, Sabine, Alouani, Sami, Mueller, Christoph, Chvatchko, Yolande, Brunner, Thomas

“…Acute graft-versus-host disease (GvHD) is a serious complication after allogeneic bone marrow transplantation. Donor-derived T cells infiltrate recipient…”
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100 - Blocking Interleukin-15 as a New Strategy for the Treatment of Eosinophilic Esophagitis by Vicari, Alain, Goffin, Laurence, Schoepfer, Alain M., Straumann, Alex, Safroneeva, Ekaterina, Simon, Hans-Uwe, Chvatchko, Yolande

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Blocking Interleukin-15 as a New Strategy for the Treatment of Eosinophilic Esophagitis by Vicari, Alain, Goffin, Laurence, Schoepfer, Alain M, Straumann, Alex, Safroneeva, Ekaterina, Simon, Hans-Uwe, Chvatchko, Yolande

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Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis by Vicari, Alain P, Schoepfer, Alain M, Meresse, Bertrand, Goffin, Laurence, Léger, Olivier, Josserand, Soheila, Guégan, Nicolas, Yousefi, Shida, Straumann, Alex, Cerf-Bensussan, Nadine, Simon, Hans-Uwe, Chvatchko, Yolande

“…Interleukin-15 (IL-15) is a critical regulator of immune responses, especially at mucosal interfaces within the gastro-intestinal tract. Here, we describe the…”
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