Search Results - "Chvanov, M"

Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell death by Athwal, T, Huang, W, Mukherjee, R, Latawiec, D, Chvanov, M, Clarke, R, Smith, K, Campbell, F, Merriman, C, Criddle, D, Sutton, R, Neoptolemos, J, Vlatković, N

“…Hereditary pancreatitis (HP) is an autosomal dominant disease that displays the features of both acute and chronic pancreatitis. Mutations in human cationic…”
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Free radicals and the pancreatic acinar cells: role in physiology and pathology by Chvanov, M, Petersen, O.H, Tepikin, A

“…Reactive oxygen and nitrogen species (ROS and RNS) play an important role in signal transduction and cell injury processes. Nitric oxide synthase (NOS)—the key…”
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Therapeutic potential of pyruvate in acute pancreatitis: In Vitro findings and a systematic review by Huang, W, Xiong, J.J, Cheng, C.R, Szatmary, P, Chvanov, M, Criddle, D.N, Xia, Q, Sutton, R

“…Background: In acute pancreatitis (AP) there is an increase in glycolysis in pancreatic acinar cells (PACs), providing ATP during mitochondrial impairment…”
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TRO40303 reduces mitochondrial injury and ameliorates experimental acute pancreatitis by Javed, M. Ahsan, Wen, L, Awais, M, Chvanov, M, Bordet, T, Michaud, M, Schaller, S, Pruss, R, Tepikin, A, Criddle, D, Sutton, R

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The role of receptor interacting protein kinase 1 (RIPK1) in bile acid-induced pancreatic acinar cell death by Ouyang, Yulin, Voronina, S, Chvanov, M, Wen, L, Latawiec, D, Awais, M, Armstrong, J.A, Bertin, J, Gough, P.J, Tepikin, A, Mukherjee, R, Sutton, R, Criddle, D.N

“…The effects of RIPK1 inhibitors on bile acid (500 [micro]M TLCS)-induced necrotic (Propidium iodide; PI) and apoptotic (caspase3/7 Green) cell death pathway…”
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Da-Cheng-Qi Decoction (DCQD) protects against pancreatic damage in murine experimental acute pancreatitis (AP) by Huang, W, Jin, T, Javed, M.A, Wen, L, Nunes, Q.M, Chvanov, M, Tepikin, A, Criddle, D.N, Xia, Q, Sutton, R

“…In the ARG-AP, mice received DCQD at 24 and 48 h after the 1st injection of L-Arginine, and were sacrificed at 72 h. In the TLCS-AP, DCQD was administered 2 h…”
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Da-Cheng-Qi decoction protects against pancreatic damage in murine experimental acute pancreatitis by Huang, W, Jin, T, Javed, M.A, Wen, L, Nunes, Q.M, Chvanov, M, Tepikin, A, Criddle, D.N, Xia, Q, Sutton, R

“…In the ARG-AP, mice received DCQD at 24 and 48 h after the 1st injection of L-Arginine, and were sacrificed at 72 h. In the TLCS-AP, DCQD was administered 2 h…”
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Rat hippocampal neurons maintain their own GABAergic synaptic transmission in culture by Melnick, I.V, Chvanov, M.A, Belan, P.V

“…The whole-cell patch-clamp technique was used to record monosynaptic inhibitory postsynaptic currents (IPSCs) from pairs of hippocampal neurons cultured for…”
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Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models by Wen, Li, Voronina, Svetlana, Javed, Muhammad A, Awais, Muhammad, Szatmary, Peter, Latawiec, Diane, Chvanov, Michael, Collier, David, Huang, Wei, Barrett, John, Begg, Malcolm, Stauderman, Ken, Roos, Jack, Grigoryev, Sergey, Ramos, Stephanie, Rogers, Evan, Whitten, Jeff, Velicelebi, Gonul, Dunn, Michael, Tepikin, Alexei V, Criddle, David N, Sutton, Robert

“…Background & Aims Sustained activation of the cytosolic calcium concentration induces injury to pancreatic acinar cells and necrosis. The calcium…”
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Nifedipine-induced morphological differentiation of rat pheochromocytoma cells by Starikova, A.M, Chvanov, M.A, Pogorelaya, N.Ch, Kostyuk, P.G

“…Extension of neuronal processes is fundamental for the establishment of the intricate network of the nervous system. The rat PC12 pheochromocytoma cell line is…”
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Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis by Chvanov, Michael, Faveri, Francesca, Moore, Danielle, Sherwood, Mark W., Awais, Muhammad, Voronina, Svetlana, Sutton, Robert, Criddle, David N., Haynes, Lee, Tepikin, Alexei V.

“…Key points Giant trypsin‐containing endocytic vacuoles are formed in pancreatic acinar cells stimulated with inducers of acute pancreatitis. F‐actin envelops…”
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Prolonged Decay of Evoked Inhibitory Postsynaptic Currents in Hippocampal Neurons Is Not Shaped by Asynchronous Release by Stepanyuk, A, Chvanov, M, Ivanov, A, Boychuk, Y, Pivneva, T, Belan, P

“…During evoked release, several quanta of neurotransmitter are synchronously released in several GABA-ergic synapses. Assuming that not more than one vesicle is…”
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L-histidine but not other basic amino acid-induced pancreatitis in mice involves inositol trisphosphate receptor signalling and mitochondrial permeability transition by Zhang, Xiaoying, Yao, Linbo, Shi, Na, Yang, Xinmin, Du, Dan, Liu, Tingting, Szatmary, Peter, Mukherjee, Rajarshi, Xia, Qing, Criddle, David, Huang, Wei, Chvanov, Michael, Tepikin, Alexey, Sutton, Robert

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Distributions of interevent intervals for miniature inhibitory and excitatory postsynaptic currents in cultured hippocampal neurons by Chvanov, M. A., Boychuk, Ya. A., Melnick, I. V., Belan, P. V., Kostyuk, P. G.

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Glutamate-induced suppression of inhibitory synaptic transmission in cultivated hippocampal neurons by Chvanov, M. A., Belan, P. V., Teslenko, V. I., Mel'nik, I. V.

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ZYMOGEN GRANULE EXOCYTOSIS IN RESPONSE TO DIRECT ACTIVATION OF CHOLECYSTOKININ RECEPTORS ON ISOLATED HUMAN PANCREATIC ACINAR CELLS by Murphy, J. A., Criddle, D. N., Sherwood, M., Chvanov, M., Mclaughlin, E., Gerasimenko, J. V., Raraty, M. G. T., Ghaneh, P., Neoptolemos, J. P., Gerasmenko, O. V., Tepikin, A. V., Green, G. M., Reeve, J. R., Petersen, O. H., Sutton, R.

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Pharmacologically directed cell disposal: labeling damaged cells for phagocytosis as a strategy against acute pancreatitis by Chvanov, Michael, Petersen, Ole H, Tepikin, Alexei V

“…Acute pancreatitis is a common clinical condition, which lacks effective pharmacological treatment. The severity of the disease is determined by the extent of…”
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Nonuniformity of calcium efflux from pancreatic acinar cells and its analysis by mathematical model of calcium diffusion and buffering in extracellular solution by Belan, P. V., Saftenku, E. É., Gerasimenko, O. V., Pogorelaya, N. Ch, Chvanov, M. A., Teslenko, V. I.

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Nifedipine-dependent changes in morphological differentiation and the cytosolic calcium content in rat pheochromocytoma cells by Starikova, A. M., Chvanov, M. A., Pogore'aya, N. Ch

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