Search Results - "Chuyue Pan"
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Flavonoid VI-16 protects against DSS-induced colitis by inhibiting Txnip-dependent NLRP3 inflammasome activation in macrophages via reducing oxidative stress
Published in Mucosal immunology (01-09-2019)“…Emerging evidence suggests that NLRP3 inflammasome was associated with various kinds of immunological diseases including colitis. However, there are few drugs…”
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Chitosan Oligosaccharide Ameliorates Nonalcoholic Fatty Liver Disease (NAFLD) in Diet-Induced Obese Mice
Published in Marine drugs (02-07-2019)“…Nonalcoholic fatty liver disease (NAFLD) is a global epidemic, and there is no standard and efficient therapy for it. Chitosan oligosaccharide (COS) is widely…”
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Small molecule GL-V9 protects against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy
Published in Oncoimmunology (02-01-2018)“…Emerging evidence suggests that NLRP3 inflammasome provides a link between colitis-associated colorectal cancer and inflammatory bowel diseases. Autophagy is…”
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Universal quantum obfuscation for quantum non-linear functions
Published in Frontiers in physics (04-01-2023)“…Research on quantum cryptography has burgeoned in the recent decades and combined quantum mechanics and cryptography theory. Among the existing quantum…”
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Alcohol drinking alters oral microbiota to modulate the progression of alcohol-related liver disease
Published in iScience (20-10-2023)“…Alcohol-related liver disease (ALD) is one of the leading causes of liver-related death worldwide. However, roles of oral microbiota in regulating the…”
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Amlodipine, an anti‐hypertensive drug, alleviates non‐alcoholic fatty liver disease by modulating gut microbiota
Published in British journal of pharmacology (01-05-2022)“…Background and Purpose Non‐alcoholic fatty liver disease (NAFLD) represents a severe public health problem. It often coexists with hypertension in the context…”
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Role of Gut Microbiota in the Pharmacological Effects of Natural Products
Published in Evidence-based complementary and alternative medicine (01-01-2019)“…Increasing evidence has demonstrated that natural products derived from traditional Chinese medicine, such as ginseng, berberine, and curcumin, possess a wide…”
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Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
Published in Cell metabolism (05-12-2023)“…Metabolic dysfunction-associated steatohepatitis (MASH) is a leading risk factor for liver cirrhosis and hepatocellular carcinoma. Here, we report that CHRNA4,…”
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Coordinated changes of gut microbiome and lipidome differentiates nonalcoholic steatohepatitis (NASH) from isolated steatosis
Published in Liver international (01-03-2020)“…Background & Aims Nonalcoholic fatty liver disease encompasses isolated steatosis or nonalcoholic fatty liver and nonalcoholic steatohepatitis (NASH). NASH…”
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YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity
Published in Proceedings of the National Academy of Sciences - PNAS (23-07-2019)“…Fibroblast growth factor 21 (FGF21) is an endocrine hormone that regulates glucose, lipid, and energy homeostasis. While gene expression of FGF21 is regulated…”
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715 ARYL HYDROCARBON RECEPTOR DEFICIENCY IN INTESTINAL EPITHELIAL CELLS AGGRAVATES ALCOHOL-RELATED LIVER DISEASE
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2021)Get full text
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Aryl Hydrocarbon Receptor Deficiency in Intestinal Epithelial Cells Aggravates Alcohol-Related Liver Disease
Published in Cellular and molecular gastroenterology and hepatology (01-01-2022)“…The ligand-activated transcription factor, aryl hydrocarbon receptor (AHR) can sense xenobiotics, dietary, microbial, and metabolic cues. Roles of Ahr in…”
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Aryl Hydrocarbon Receptor Deficiency in Intestinal Epithelial Cells Aggravates Alcohol-Related Liver DiseaseSummary
Published in Cellular and molecular gastroenterology and hepatology (01-01-2022)“…Background & Aims: The ligand-activated transcription factor, aryl hydrocarbon receptor (AHR) can sense xenobiotics, dietary, microbial, and metabolic cues…”
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Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice
Published in Cellular and molecular gastroenterology and hepatology (01-01-2021)“…Fucosyltransferase 2 (Fut2)-mediated intestinal α1- 2-fucosylation is important for host–microbe interactions and has been associated with several diseases,…”
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Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in MiceSummary
Published in Cellular and molecular gastroenterology and hepatology (01-01-2021)“…Background & Aims: Fucosyltransferase 2 (Fut2)-mediated intestinal α1- 2-fucosylation is important for host–microbe interactions and has been associated with…”
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