Search Results - "Chuva de Sousa Lopes, S  M"

Single-cell reconstruction of follicular remodeling in the human adult ovary by Fan, X., Bialecka, M., Moustakas, I., Lam, E., Torrens-Juaneda, V., Borggreven, N. V., Trouw, L., Louwe, L. A., Pilgram, G. S. K., Mei, H., van der Westerlaken, L., Chuva de Sousa Lopes, S. M.

“…The ovary is perhaps the most dynamic organ in the human body, only rivaled by the uterus. The molecular mechanisms that regulate follicular growth and…”
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Human fetal microglia acquire homeostatic immune-sensing properties early in development by Kracht, L., Borggrewe, M., Eskandar, S., Brouwer, N., Chuva de Sousa Lopes, S. M., Laman, J. D., Scherjon, S. A., Prins, J. R., Kooistra, S. M., Eggen, B. J. L.

“…Microglia are the brain's immune cells, and they play important roles in health and neurodegenerative disease. Kracht et al. performed single-cell analysis of…”
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Extended in vitro culture of human embryos demonstrates the complex nature of diagnosing chromosomal mosaicism from a single trophectoderm biopsy by Popovic, M, Dhaenens, L, Taelman, J, Dheedene, A, Bialecka, M, De Sutter, P, Chuva de Sousa Lopes, S M, Menten, B, Heindryckx, B

“…Abstract STUDY QUESTION What is the accuracy of preimplantation genetic testing for aneuploidies (PGT-A) when considering human peri-implantation outcomes in…”
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Various repair events following CRISPR/Cas9-based mutational correction of an infertility-related mutation in mouse embryos by Bekaert, B., Boel, A., Rybouchkin, A., Cosemans, G., Declercq, S., Chuva de Sousa Lopes, S. M., Parrington, J., Stoop, D., Coucke, P., Menten, B., Heindryckx, B.

“…Purpose Unpredictable genetic modifications and chromosomal aberrations following CRISPR/Cas9 administration hamper the efficacy of germline editing. Repair…”
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Two decades of embryonic stem cells: a historical overview by Eguizabal, C, Aran, B, Chuva de Sousa Lopes, S M, Geens, M, Heindryckx, B, Panula, S, Popovic, M, Vassena, R, Veiga, A

“…Abstract STUDY QUESTION How did the field of stem cell research develop in the years following the derivation of the first human embryonic stem cell (hESC)…”
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Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences by Stamatiadis, P, Boel, A, Cosemans, G, Popovic, M, Bekaert, B, Guggilla, R, Tang, M, De Sutter, P, Van Nieuwerburgh, F, Menten, B, Stoop, D, Chuva de Sousa Lopes, S M, Coucke, P, Heindryckx, B

“…What is the role of POU class 5 homeobox 1 (POU5F1) in human preimplantation development and how does it compare with the mouse model? POU5F1 is required for…”
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Targeted disruption of the synovial sarcoma-associated SS18 gene causes early embryonic lethality and affects PPARBP expression by de Bruijn, D.R.H., Peters, W.J.M., Chuva de Sousa Lopes, S.M., van Dijk, A.H.A., Willemse, M.P., Pfundt, R., de Boer, P., Geurts van Kessel, A.

“…The synovial sarcoma-associated protein SS18 (also known as SYT or SSXT) is thought to act as a transcriptional co-activator. This activity appears to be…”
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Differential expression of the MHM region and of sex-determining-related genes during gonadal development in chicken embryos by Caetano, L C, Gennaro, F G O, Coelho, K, Araújo, F M, Vila, R A, Araújo, A, de Melo Bernardo, A, Marcondes, C R, Chuva de Sousa Lopes, S M, Ramos, E S

“…The chicken (Gallus gallus) embryo has been used as a classic model system for developmental studies because of its easy accessibility for surgical…”
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TEAD4 regulates trophectoderm differentiation upstream of CDX2 in a GATA3-independent manner in the human preimplantation embryo by Stamatiadis, P, Cosemans, G, Boel, A, Menten, B, De Sutter, P, Stoop, D, Chuva de Sousa Lopes, S M, Lluis, F, Coucke, P, Heindryckx, B

“…What is the role of transcriptional-enhanced associate (TEA) domain family member 4 (TEAD4) in trophectoderm (TE) differentiation during human embryo…”
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A new advanced stem cell-based embryonic model: The ultimate model? by Declercq, S., Chuva de Sousa Lopes, S.M., Heindryckx, B.

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Characterization of ovarian tissue oocytes from transgender men reveals poor calcium release and embryo development, which might be overcome by spindle transfer by Christodoulaki, A, He, H, Zhou, M, Cardona Barberán, A, De Roo, C, Chuva De Sousa Lopes, S M, Baetens, M, Menten, B, Van Soom, A, De Sutter, P, Weyers, S, Boel, A, Stoop, D, Heindryckx, B

“…Can spindle transfer (ST) overcome inferior embryonic development of in vitro matured ovarian tissue oocytes (OTO-IVM) originating from testosterone-treated…”
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Transcriptional landscape changes during human embryonic stem cell derivation by Warrier, S, Taelman, J, Tilleman, L, Van der Jeught, M, Duggal, G, Lierman, S, Popovic, M, Van Soom, A, Peelman, L, Van Nieuwerburgh, F, Deforce, D, Chuva de Sousa Lopes, S M, De Sutter, P, Heindryckx, B

“…What are the transcriptional changes occurring during the human embryonic stem cell (hESC) derivation process, from the inner cell mass (ICM) to post-ICM…”
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Extended In Vitro Culture of Human Embryos Demonstrates the Complex Nature of Diagnosing Chromosomal Mosaicism From a Single Trophectoderm Biopsy by Popovic, M, Dhaenens, L, Taelman, J, Dheedene, A, Bialecka, M, De Sutter, P, de Sousa Lopes, S. M Chuva, Menten, B, Heindryckx, B

“…(Abstracted from Hum Reprod 2019;34(4):758–769)The development of preimplantation genetic testing (PGT-A) in conjunction with assisted reproductive technology…”
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O-055 Understanding endometrial functionality and embryo-maternal communication via in vitro “OMICs’’ platforms by Chuva de Sousa Lopes, S M

“…The uterus (womb) is perhaps the most fascinating organ in the human body. It undergoes cyclical regeneration of its inner layer, the endometrium, and is…”
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P-355 Effect of biphasic CAPA-IVM on ovarian tissue oocytes of transgender men by Fakhar I Adil, M, Christodoulaki, A, Chuva de Sousa Lopes, S  M, Weyers, S, Menten, B, Van Soom, A, Stoop, D, De Roo, C, Heindryckx, B

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P-794 Unraveling the function of GATA2 and GATA3 in mouse blastocyst formation via CRISPR/Cas9 gene editing by Declercq, S, Cosemans, G, Boel, A, Stoop, D, Chuva de Sousa Lopes, S  M, Coucke, P, Lluis Vinas, F, Heindryckx, B

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P-431 Effect of biphasic CAPA-IVM on ovarian tissue oocytes of transgender men by Fakhar I Adil, M, Christodoulaki, A, Boel, A, Chuva de Sousa Lopes, S M, Menten, B, Van Soom, A, Stoop, D, De roo, C, Heindryckx, B

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P-802 TFAP2C is required for proper segregation of developmental markers regulating trophectoderm commitment during mouse preimplantation development by Cosemans, G, Boel, A, Bekaert, B, Stoop, D, Chuva de Sousa Lopes, S M, Coucke, P, Menten, B, Lluís Viñas, F, Heindryckx, B

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O-030 The impact of aneuploidy on human peri-implantation development: findings from the extended in vitro culture of 191 human embryos by Azpiroz, F, Torra Massana, M, Quintana-Vehí, A, Pujol, A, Franco Iriarte, J M, Lledó, B, Millet Teruel, G, Aurell, R, Pérez de la Blanca, E, Fernández, C, Urries, A, Rodríguez-Aranda, A, Chuva De Sousa Lopes, S M, Popovic, M

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P-430 Characterization of secondary follicles from cultured cryopreserved-thawed human ovarian cortical tissue by Cheng, H, Chen, S, Del Valle, J S, Fan, X, Fu, W, Louwe, L A, Pilgram, G S K, Van der Westerlaken2, L A J, Chuva De Sousa Lopes, S M

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