Search Results - "Churchill, Hywyn R.O"
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Programmed death 1 expression in variant immunoarchitectural patterns of nodular lymphocyte predominant Hodgkin lymphoma: comparison with CD57 and lymphomas in the differential diagnosis
Published in Human pathology (01-12-2010)“…Summary Recent studies have exploited an antibody directed against programmed death 1 expressed by follicular helper T-cells in the diagnosis of nodular…”
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A practical synthesis of the 5-chloromethyl-furo[2,3-b]pyridine pharmacophore
Published in Tetrahedron letters (26-06-1995)“…Synthesis of the furopyridine 2 was accomplished in 52% overall yield from 6-hydroxynicotinic acid ( 3). The synthesis is highighted by a Heck coupling of 5…”
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Leukocyte immunoglobulin‐like receptor B1 and B4 (LILRB1 and LILRB4): Highly sensitive and specific markers of acute myeloid leukemia with monocytic differentiation
Published in Cytometry. Part B, Clinical cytometry (01-07-2021)“…Background Acute myeloid leukemia (AML) with monocytic differentiation (M‐AML) remains a diagnostic challenge largely due to lack of sensitive and specific…”
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Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists
Published in Nature medicine (01-06-2007)“…Exotoxins of Staphylococcus aureus belong to a family of bacterial proteins that act as superantigens by activating a large subset of the T-cell population,…”
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Role of 2c T Cell Receptor Residues in the Binding of Self–And Allo–Major Histocompatibility Complexes
Published in The Journal of experimental medicine (17-04-2000)“…T cell clone 2C recognizes the alloantigen Ld and the positive selecting major histocompatibility complex (MHC), Kb. To explore the molecular basis of T cell…”
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Directed evolution of T-cell receptors for binding superantigens
Published in Methods in molecular biology (Clifton, N.J.) (2003)Get more information
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Analysis of superantigen binding to soluble T-cell receptors
Published in Methods in molecular biology (Clifton, N.J.) (2003)Get more information
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Mapping the energy of superantigen Staphylococcus enterotoxin C3 recognition of an alpha/beta T cell receptor using alanine scanning mutagenesis
Published in The Journal of experimental medicine (06-03-2000)“…Binding of the T cell receptor (TCR) to a bacterial superantigen (SAG) results in stimulation of a large population of T cells and subsequent inflammatory…”
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Crystallization-induced asymmetric transformation: Stereospecific synthesis of L-768,673
Published in Tetrahedron (22-01-1999)“…A highly convergent, asymmetric synthesis of L-768,673, an I ks Class III antiarrythmic drug candidate, is described. Synthesis of the recemic…”
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An Unusual Stereoselective Decarboxylation: A Key Reaction to an Important Intermediate for Carbapenem Antibiotics
Published in Journal of organic chemistry (01-12-1995)Get full text
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A facially-selective protonation controls the stereochemistry of a key intermediate in the synthesis of 1β-methylcarbapenems
Published in Journal of organic chemistry (15-07-1994)Get full text
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