Search Results - "Churchill, Gwydion H"

Enantioselective Rh(I)-Catalyzed Cyclization of Arylboron Compounds onto Ketones by Low, Darryl W, Pattison, Graham, Wieczysty, Martin D, Churchill, Gwydion H, Lam, Hon Wai

“…Rhodium complexes based upon chiral sulfinamide–alkene, TADDOL-derived phosphoramidite, or diene ligands catalyze cyclizations of arylboron compounds onto…”
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Hydride Shift Generated Oxonium Ions: Evidence for Mechanism and Intramolecular Trapping Experiments to Form trans THF Derivatives by Donohoe, Timothy J, Williams, Oliver, Churchill, Gwydion H

“…Switching sides: cis THF derivatives produced from the oxidative cyclization of dienes and diols can be transformed into the corresponding trans heterocycles…”
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Stereoselective Synthesis of Pyrrolidines: Catalytic Oxidative Cyclizations Mediated by Osmium by Donohoe, Timothy J., Churchill, Gwydion H., Wheelhouse (née Gosby), Katherine M. P., Glossop, Paul A.

“…A new pathway for oxidative cyclization: N‐protected α‐amino alcohols with distal alkene units cyclize with complete stereoselectivity and stereospecificity to…”
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Osmium‐Mediated Oxidative Cyclizations: A Study into the Range of Initiators That Facilitate Cyclization by Donohoe, Timothy J., Wheelhouse (née Gosby), Katherine M. P., Lindsay‐Scott, Peter J., Churchill, Gwydion H., Connolly, Matthew J., Butterworth, Sam, Glossop, Paul A.

“…A general route to prepare substituted, saturated five‐membered heterocycles has been developed. The application of a wide range of starting materials to the…”
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Improved synthesis of substituted pyrido[2,3-d]pyrimidinediones by Churchill, Gwydion H., Raw, Steven A., Powell, Lyn

“…An improved methodology for the synthesis of substituted pyrido[2,3-d]pyrimidinediones from 6-aminouracils and the corresponding enaminone has been developed…”
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Approaches to the quaternary stereocentre and to the heterocyclic core in diazonamide A using the Heck reaction and related coupling reactions by Booker, James E M, Boto, Alicia, Churchill, Gwydion H, Green, Clive P, Ling, Matthew, Meek, Graham, Prabhakaran, Jaya, Sinclair, David, Blake, Alexander J, Pattenden, Gerald

“…In model studies towards the quaternary centre at the heart of diazonamide A (early structure 2; revised structure 1), cyclisations of the alkene-substituted…”
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Development of the Convergent, Kilogram-Scale Synthesis of an Antibacterial Clinical Candidate Using Enantioselective Hydrogenation by Benson, Helen, Bones, Karen, Churchill, Gwydion, Ford, Gair, Frodsham, Lianne, Janbon, Sophie, Millington, Fiona, Powell, Lyn, Raw, Steven A, Reid, Julie, Stark, Andrew, Steven, Alan

“…Early chemical development studies into the best way of assembling AZD9742, an antibacterial drug candidate, have involved swapping the order of two reductive…”
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Stereoselective Synthesis of Pyrrolidines: Catalytic Oxidative Cyclizations Mediated by Osmium by Donohoe, Timothy J., Churchill, Gwydion H., Wheelhouse (née Gosby), Katherine M. P., Glossop, Paul A.

“…Ein neuer Weg der oxidativen Cyclisierung: N‐geschützte α‐Aminoalkohole mit distalen Alkeneinheiten cyclisieren – abhängig vom Substitutionsmuster – unter…”
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Regio and stereoselective catalytic five-component cascades of diverse heterocyclic bisallenes: tri-directional exploration of biochemical space by Elboray, Elghareeb E., Aly, Moustafa F., Abbas-Temirek, Hussien H., Churchill, Gwydion H., Grigg, Ronald

“…We report protecting group free Pd(0) catalyzed cascade syntheses of molecular scaffolds built from heterocyclic bisallenes. These generate novel molecular…”
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Hydride Shift Generated Oxonium Ions: Evidence for Mechanism and Intramolecular Trapping Experiments to Form trans THF Derivatives by Donohoe, Timothy J., Williams, Oliver, Churchill, Gwydion H.

“…Seitenwechsel: cis‐substituierte THF‐Derivate, die durch oxidative Cyclisierung von Dienen und Diolen erhalten wurden, werden durch eine 1,2‐Hydridwanderung…”
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Hydride Shift Generated Oxonium Ions: Evidence for Mechanism and Intramolecular Trapping Experiments to Form trans THF Derivatives by Donohoe, Timothy J., Williams, Oliver, Churchill, Gwydion H.

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Stereoselective Synthesis of Pyrrolidines: Catalytic Oxidative Cyclizations Mediated by Osmium by Donohoe, Timothy J., Churchill, Gwydion H., Wheelhouse (née Gosby), Katherine M. P., Glossop, Paul A.

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