Search Results - "Church, K"

The role and relevance of mast cells in urticaria by Church, Martin K., Kolkhir, Pavel, Metz, Martin, Maurer, Marcus

“…Summary This review presents evidence that the skin mast cell, in particular the MCTC subtype, is the primary effector cell in urticaria. Mast cells are…”
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Predictors of treatment response in chronic spontaneous urticaria by Fok, Jie Shen, Kolkhir, Pavel, Church, Martin K., Maurer, Marcus

“…The current therapeutic algorithm for chronic spontaneous urticaria (CSU), endorsed by the international guideline, entails treatment escalation from…”
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Omalizumab is an effective and rapidly acting therapy in difficult-to-treat chronic urticaria: A retrospective clinical analysis by Metz, Martin, Ohanyan, Tatevik, Church, Martin K, Maurer, Marcus

“…Abstract Background Omalizumab (anti-IgE) therapy is effective and safe in chronic urticaria (CU) in placebo-controlled clinical trials but real life clinical…”
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The Role of Histamine and Histamine Receptors in Mast Cell-Mediated Allergy and Inflammation: The Hunt for New Therapeutic Targets by Thangam, Elden Berla, Jemima, Ebenezer Angel, Singh, Himadri, Baig, Mirza Saqib, Khan, Mahejibin, Mathias, Clinton B, Church, Martin K, Saluja, Rohit

“…Histamine and its receptors (H1R-H4R) play a crucial and significant role in the development of various allergic diseases. Mast cells are multifunctional bone…”
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Serum autoreactivity predicts time to response to omalizumab therapy in chronic spontaneous urticaria by Gericke, Janine, PhD, Metz, Martin, MD, Ohanyan, Tatevik, MD, Weller, Karsten, MD, Altrichter, Sabine, MD, Skov, Per Stahl, MD, Falkencrone, Sidsel, PhD, Brand, Janko, PhD, Kromminga, Arno, PhD, Hawro, Tomasz, MD, Church, Martin K., PhD, DSc, Maurer, Marcus, MD

“…The cutoff time of 8 days between fast and slow responders was chosen because it corresponds with the peak plasma level of omalizumab after its initial…”
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Development and validation of the Urticaria Control Test: A patient-reported outcome instrument for assessing urticaria control by Weller, Karsten, MD, Groffik, Adriane, MD, Church, Martin K., PhD, DSc, Hawro, Tomasz, MD, Krause, Karoline, MD, Metz, Martin, MD, Martus, Peter, PhD, Casale, Thomas B., MD, Staubach, Petra, MD, Maurer, Marcus, MD

“…Background Chronic urticaria is a frequent and debilitating skin disease. Its symptoms commonly fluctuate considerably from day to day. As of yet, the only…”
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The role of eosinophils in chronic spontaneous urticaria by Altrichter, Sabine, Frischbutter, Stefan, Fok, Jie Shen, Kolkhir, Pavel, Jiao, Qingqing, Skov, Per Stahl, Metz, Martin, Church, Martin K., Maurer, Marcus

“…Chronic spontaneous urticaria (CSU) is considered to be primarily a mast cell–driven disease. However, recent evidence suggests that eosinophils may also have…”
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Broadening our understanding of what drives stewardship engagement: Relationships between social capital and willingness to engage in nature stewardship by K Church, Emma, A Wilson, Kerrie, J Dean, Angela

“…Diverse solutions are needed to reduce human impacts on nature. Fostering individual stewardship behaviours that protect, restore, and encourage sustainable…”
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Autoimmune chronic spontaneous urticaria: What we know and what we do not know by Kolkhir, Pavel, MD, Church, Martin K., PhD, Dsc, Weller, Karsten, MD, Metz, Martin, MD, Schmetzer, Oliver, MD, Maurer, Marcus, MD

“…Chronic spontaneous urticaria (CSU) is a mast cell–driven skin disease characterized by the recurrence of transient wheals, angioedema, or both for more than…”
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Immunoglobulin E-Mediated Autoimmunity by Maurer, Marcus, Altrichter, Sabine, Schmetzer, Oliver, Scheffel, Jörg, Church, Martin K, Metz, Martin

“…The study of autoimmunity mediated by immunoglobulin E (IgE) autoantibodies, which may be termed autoallergy, is in its infancy. It is now recognized that…”
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Cardiac safety of second‐generation H1‐antihistamines when updosed in chronic spontaneous urticaria by Cataldi, Mauro, Maurer, Marcus, Taglialatela, Maurizio, Church, Martin K.

“…The symptoms of chronic urticaria, be it chronic spontaneous urticaria (CSU) or chronic inducible urticaria (CindU), are mediated primarily by the actions of…”
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Biomarkers and clinical characteristics of autoimmune chronic spontaneous urticaria: Results of the PURIST Study by Schoepke, Nicole, Asero, Riccardo, Ellrich, André, Ferrer, Marta, Gimenez‐Arnau, Ana, E. H. Grattan, Clive, Jakob, Thilo, Konstantinou, George N., Raap, Ulrike, Skov, Per Stahl, Staubach, Petra, Kromminga, Arno, Zhang, Ke, Bindslev‐Jensen, Carsten, Daschner, Alvaro, Kinaciyan, Tamar, Knol, Edward F., Makris, Michael, Marrouche, Nadine, Schmid‐Grendelmeier, Peter, Sussman, Gordon, Toubi, Elias, Church, Martin K., Maurer, Marcus

“…Background Autoimmune chronic spontaneous urticaria (aiCSU) is an important subtype of chronic spontaneous urticaria (CSU) in which functional IgG…”
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Efficacy and safety of canakinumab in Schnitzler syndrome: A multicenter randomized placebo-controlled study by Krause, Karoline, MD, Tsianakas, Athanasios, MD, Wagner, Nicola, MD, Fischer, Jörg, MD, Weller, Karsten, MD, Metz, Martin, MD, Church, Martin K., PhD, Maurer, Marcus, MD

“…Background Schnitzler syndrome is an adult-onset autoinflammatory disease characterized by urticarial exanthema and monoclonal gammopathy accompanied by…”
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Potential blood biomarkers in chronic spontaneous urticaria by Kolkhir, P., André, F., Church, M. K., Maurer, M., Metz, M.

“…Summary Chronic spontaneous urticaria (CSU) is a mast cell‐driven disease that is defined as the recurrence of weals, angioedema or both for > 6 weeks due to…”
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The potential pharmacologic mechanisms of omalizumab in patients with chronic spontaneous urticaria by Chang, Tse Wen, PhD, Chen, Christina, BS, Lin, Chien-Jen, PhD, Metz, Martin, MD, Church, Martin K., PhD, DSc, Maurer, Marcus, MD

“…In patients given a diagnosis of chronic spontaneous urticaria (CSU), there are no obvious external triggers, and the factors that initiate the clinical…”
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Mast cells, cortistatin, and its receptor, MRGPRX2, are linked to the pathogenesis of chronic prurigo by Kolkhir, Pavel, Pyatilova, Polina, Ashry, Tameem, Jiao, Qingqing, Abad-Perez, Angela Teresa, Altrichter, Sabine, Vera Ayala, Carolina Elisa, Church, Martin K., He, Jiajun, Lohse, Katharina, Metz, Martin, Scheffel, Jörg, Türk, Murat, Frischbutter, Stefan, Maurer, Marcus

“…Chronic prurigo (CPG) is characterized by intensive itch and interactions among nerves, neuropeptides, and mast cells (MCs). The role of some neuropeptides…”
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Interleukin‐17 is a potential player and treatment target in severe chronic spontaneous urticaria by Sabag, D. A., Matanes, L., Bejar, J., Sheffer, H., Barzilai, A., Church, M. K., Toubi, E., Maurer, M., Vadasz, Z.

“…Background Chronic spontaneous urticaria (CSU) is considered an autoimmune disorder in 50% of cases at least, in which T‐ and mast cell mediators are…”
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The role of IL‐33 and mast cells in allergy and inflammation by Saluja, Rohit, Khan, Mahejibin, Church, Martin K., Maurer, Marcus

“…Interleukin‐33 (IL‐33) is a member of the interleukin‐1 (IL‐1) cytokine family. It is preferentially and constitutively expressed in different structural cells…”
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The Role of Auditor Narcissism in Auditor‐Client Negotiations: Evidence from China by Church, Bryan K., Dai, Narisa Tianjing, Kuang, Xi (Jason), Liu, Xuejiao

“…ABSTRACT This paper reports the results of three studies (archival, experimental, and qualitative) designed to examine the effects of auditor narcissism on…”
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Up‐dosing with bilastine results in improved effectiveness in cold contact urticaria by Krause, K., Spohr, A., Zuberbier, T., Church, M. K., Maurer, M.

“…Background Cold contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of histamine and other pro‐inflammatory…”
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