Search Results - "Church, Alanna J."

Recurrent EML4–NTRK3 fusions in infantile fibrosarcoma and congenital mesoblastic nephroma suggest a revised testing strategy by Church, Alanna J, Calicchio, Monica L, Nardi, Valentina, Skalova, Alena, Pinto, Andre, Dillon, Deborah A, Gomez-Fernandez, Carmen R, Manoj, Namitha, Haimes, Josh D, Stahl, Joshua A, Dela Cruz, Filemon S, Tannenbaum-Dvir, Sarah, Glade-Bender, Julia L, Kung, Andrew L, DuBois, Steven G, Kozakewich, Harry P, Janeway, Katherine A, Perez-Atayde, Antonio R, Harris, Marian H

“…Infantile fibrosarcoma and congenital mesoblastic nephroma are tumors of infancy traditionally associated with the ETV6–NTRK3 gene fusion. However, a number of…”
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Recurrent and novel USP6 fusions in cranial fasciitis identified by targeted RNA sequencing by Paulson, Vera A., Stojanov, Ivan A., Wasman, Jay K., Restrepo, Tamara, Cano, Samantha, Plunkitt, Joanna, Duraisamy, Sekhar, Harris, Marian H., Chute, Deborah J., Al-Ibraheemi, Alyaa, Church, Alanna J.

“…Cranial fasciitis is a benign myofibroproliferative lesion of the scalp and underlying bones typically occurring in the pediatric population. Histologically,…”
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Expanding the Spectrum of Perioral Myogenic Tumors in Pediatric Patients: An SRF::NCOA2 Fused Perivascular Tumor of the Philtrum by Slack, Jonathan C., Hollowell, Monica L., Khouri, Kimberly S., Church, Alanna J., Ganske, Ingrid M., Delano, Sophia, Al-Ibraheemi, Alyaa

“…Background: Perivascular tumors, which include myopericytoma and myofibroma, are rare benign soft tissue neoplasms composed of perivascular smooth muscle…”
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MicroRNA Signature Obtained From the Comparison of Aggressive With Indolent Non-Hodgkin Lymphomas: Potential Prognostic Value in Mantle-Cell Lymphoma by GOSWAMI, Rashmi S, ATENAFU, Eshetu G, LAI, Raymond, CHURCH, Alanna J, LAM, Wilson S, BAETZ, Tara, LEBRUN, David P, SEHN, Laurie H, FARINHA, Pedro, JURISICA, Igor, BAILEY, Denis J, GASCOYNE, Randy D, YALI XUAN, CRUMP, Michael, KAMEL-REID, Suzanne, WALDRON, Levi, REIS, Patricia P, SUN, Thomas, DATTI, Alessandro, WEI XU, KURUVILLA, John, GOOD, David J

“…Mantle-cell lymphoma (MCL) has a variable natural history but is incurable with current therapies. MicroRNAs (miRs) are useful in prognostic assessment of…”
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A single‐institution pediatric and young adult interventional oncology collaborative: Novel therapeutic options for relapsed/refractory solid tumors by Shaikh, Raja, Weil, Brent R., Weldon, Christopher B., Chen, Nan, London, Wendy B., Krush, Morgan, Anderson, Megan, Gebhardt, Mark, Church, Alanna J., DuBois, Steven G., Pikman, Yana, Spidle, Jennifer, Wall, Catherine B., Feraco, Angela, Ullrich, Nicole J., Mack, Jennifer W., Mullen, Elizabeth, Kamihara, Junne, Forrest, Suzanne, Shusterman, Suzanne, Janeway, Katherine A., Alomari, Ahmad, Padua, Horacio, Rodriguez‐Galindo, Carlos, O'Neill, Allison F.

“…Background Pediatric interventional oncology (PIO) is a growing field intended to provide additional or alternative treatment options for pediatric patients…”
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Molecular Alterations in Pediatric Solid Tumors by Slack, Jonathan C., Church, Alanna J.

“…Pediatric tumors can be divided into hematologic malignancies, central nervous system tumors, and extracranial solid tumors of bone, soft tissue, or other…”
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New molecular insights into the pathogenesis of lipoblastomas: clinicopathologic, immunohistochemical, and molecular analysis in pediatric cases by Lopez-Nunez, Oscar, Alaggio, Rita, Ranganathan, Sarangarajan, Schmitt, Lori, John, Ivy, Church, Alanna J., Picarsic, Jennifer

“…Lipoblastomas can occasionally require further molecular confirmation when occurring outside of the usual age groups or demonstrating unusual morphology. We…”
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The implementation of molecular tumor profiling in the practice of pediatric cancer pathology: The pathologists' experience by Gestrich, Catherine K, Kreiger, Portia, Surrey, Lea, Besmer, Sherri, Lopez-Terrada, Dolores, Church, Alanna J

“…The increased accessibility and utilization of molecular testing including next-generation sequencing (NGS) has impacted the practice of pediatric pathology,…”
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Section E6.7-6.12 of the American College of Medical Genetics and Genomics (ACMG) Technical Laboratory Standards: Cytogenomic studies of acquired chromosomal abnormalities in solid tumors by Church, Alanna J., Akkari, Yassmine, Deeb, Kristin, Kolhe, Ravindra, Lin, Fumin, Spiteri, Elizabeth, Wolff, Daynna J., Shao, Lina

“…Clinical cytogenomic studies of solid tumor samples are critical to the diagnosis, prognostication, and treatment selection for cancer patients. An overview of…”
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Special Considerations in the Molecular Diagnostics of Pediatric Neoplasms by Fisch, Adam S., Church, Alanna J.

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Splenic Lymphatic Malformation With Papillary Endothelial Proliferation: A Rare Histologic Variant or a Unique Entity? by Slack, Jonathan C., Putra, Juan, Callahan, Michael J., Church, Alanna J., Teot, Lisa A., Eng, Whitney, Perez-Atayde, Antonio R.

“…Lymphatic malformations (LMs) are congenital anomalies of the lymphatic system due to abnormalities that occur during the development of the lymphovascular…”
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A somatic activating NRAS variant associated with kaposiform lymphangiomatosis by Barclay, Sarah F., Inman, Kyle W., Luks, Valerie L., McIntyre, John B., Al-Ibraheemi, Alyaa, Church, Alanna J., Perez-Atayde, Antonio R., Mangray, Shamlal, Jeng, Michael, Kreimer, Sara R., Walker, Lori, Fishman, Steven J., Alomari, Ahmad I., Chaudry, Gulraiz, Trenor, Cameron C., Adams, Denise, Kozakewich, Harry P.W., Kurek, Kyle C.

“…Kaposiform lymphangiomatosis (KLA) is a rare, frequently aggressive, systemic disorder of the lymphatic vasculature, occurring primarily in children. Even with…”
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CTNNB1 and APC Mutations in Sinonasal Myxoma: Expanding the Spectrum of Tumors Driven By WNT/β-catenin Pathway by Chen, Sonja, Gallant, Sara, Cunningham, Michael J., Robson, Caroline D., Church, Alanna J., Perez-Atayde, Antonio R., Al-Ibraheemi, Alyaa

“…Sinonasal myxoma (SNM) is a rare, benign mesenchymal neoplasm with distinct clinicopathologic features and aberrant nuclear localization of β-catenin by…”
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Next generation sequencing aids diagnosis and management in a case of encephalocraniocutaneous lipomatosis by Barry, Kelly K., Liang, Marilyn G., Balkin, Daniel M., Srivastava, Siddharth, Church, Alanna J., Eng, Whitney

“…Encephalocraniocutaneous lipomatosis (ECCL) is a rare neurocutaneous disorder caused by somatic FGFR1 and KRAS variants. It shares significant phenotypic…”
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Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children’s Oncology Group by Shulman, David S., Chen, Sonja, Hall, David, Nag, Anwesha, Thorner, Aaron R., Lessnick, Stephen L., Stegmaier, Kimberly, Janeway, Katherine A., DuBois, Steven G., Krailo, Mark D., Barkauskas, Donald A., Church, Alanna J., Crompton, Brian D.

“…Background Ewing sarcoma (EWS) is an aggressive sarcoma with no validated molecular biomarkers. We aimed to determine the frequency of STAG2 protein loss by…”
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Natural History of Thyroid Disease in Children with PTEN Hamartoma Tumor Syndrome by Smith, Jessica R, Liu, Enju, Church, Alanna J, Asch, Elizabeth, Cherella, Christine E, Srivastava, Siddharth, Kamihara, Junne, Wassner, Ari J

“…Abstract Context Thyroid ultrasound screening is recommended in children with PTEN hamartoma tumor syndrome (PHTS) due to increased risk of thyroid neoplasia,…”
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A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma by Guenther, Lillian M, Dharia, Neekesh V, Ross, Linda, Conway, Amy, Robichaud, Amanda L, Catlett, 2nd, Jerrel L, Wechsler, Caroline S, Frank, Elizabeth S, Goodale, Amy, Church, Alanna J, Tseng, Yuen-Yi, Guha, Rajarshi, McKnight, Crystal G, Janeway, Katherine A, Boehm, Jesse S, Mora, Jaume, Davis, Mindy I, Alexe, Gabriela, Piccioni, Federica, Stegmaier, Kimberly

“…Novel targeted therapeutics have transformed the care of subsets of patients with cancer. In pediatric malignancies, however, with simple tumor genomes and…”
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Thyroid Nodules in Children With Familial Adenomatous Polyposis by Smith, Jessica R., Kamihara, Junne, Church, Alanna J., Asch, Elizabeth, Cherella, Christine E., Fox, Victor L., Wassner, Ari J.

“…Ultrasound screening for thyroid cancer is recommended in familial adenomatous polyposis (FAP). This study investigated the prevalence of thyroid neoplasia in…”
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ASPSCR1::TFE3 Drives Alveolar Soft Part Sarcoma by Inducing Targetable Transcriptional Programs by Sicinska, Ewa, Kola, Vijaya S R, Kerfoot, Joseph A, Taddei, Madeleine L, Al-Ibraheemi, Alyaa, Hsieh, Yi-Hsuan, Church, Alanna J, Landesman-Bollag, Esther, Landesman, Yosef, Hemming, Matthew L

“…Alveolar soft part sarcoma (ASPS) is a rare mesenchymal malignancy driven by the ASPSCR1::TFE3 fusion. A better understanding of the mechanisms by which this…”
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PD-1 and PD-L1 Expression in Osteosarcoma: Which Specimen to Evaluate? by Chen, Sonja, Guenther, Lillian M., Aronhalt, Amanda, Cardillo, Lacey, Janeway, Katherine A., Church, Alanna J.

“…There is a growing interest in immunotherapy in childhood cancers. Osteosarcoma is a compelling potential target as there are few targeted options available…”
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