Search Results - "Chung, Sooyoung"
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Circadian rhythm of adrenal glucocorticoid: Its regulation and clinical implications
Published in Biochimica et biophysica acta (01-05-2011)“…Glucocorticoid (GC) is an adrenal steroid hormone that controls a variety of physiological processes such as metabolism, immune response, cardiovascular…”
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The adrenal peripheral clock: Glucocorticoid and the circadian timing system
Published in Frontiers in neuroendocrinology (01-10-2011)“…Highlights ► Circadian rhythm of glucocorticoid (GC) is tightly regulated by coincident multiple mechanisms. ► Adrenal local clock regulates periodic…”
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3
Programming effects of maternal stress on the circadian system of adult offspring
Published in Experimental & molecular medicine (01-03-2020)“…Maternal stress has long-lasting influences on the brain functions of offspring, and several brain regions have been proposed to mediate such programming…”
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Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex
Published in Nature (10-02-2005)“…Neurons in the cerebral cortex are organized into anatomical columns, with ensembles of cells arranged from the surface to the white matter. Within a column,…”
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Subanesthetic ketamine rapidly alters medial prefrontal miRNAs involved in ubiquitin-mediated proteolysis
Published in PloS one (26-08-2021)“…Ketamine is a dissociative anesthetic and a non-competitive NMDAR antagonist. At subanesthetic dose, ketamine can relieve pain and work as a fast-acting…”
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Functional Characterization of Circadian Nuclear Receptors REV-ERBα and REV-ERBβ in Human Osteosarcoma Cell Cultures
Published in International journal of molecular sciences (01-01-2024)“…REV-ERBα and its paralog, REV-ERBβ, encoded by and genes, are key nuclear receptors that link the circadian timing system and metabolic homeostasis. Since heme…”
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Advanced Circadian Phase in Mania and Delayed Circadian Phase in Mixed Mania and Depression Returned to Normal after Treatment of Bipolar Disorder
Published in EBioMedicine (01-09-2016)“…Disturbances in circadian rhythms have been suggested as a possible cause of bipolar disorder (BD). Included in this study were 31 mood episodes of 26 BD…”
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Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production
Published in Proceedings of the National Academy of Sciences - PNAS (30-12-2008)“…Glucocorticoid (GC) is an adrenal steroid with diverse physiological effects. It undergoes a robust daily oscillation, which has been thought to be driven by…”
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Adrenal peripheral oscillator in generating the circadian glucocorticoid rhythm
Published in Annals of the New York Academy of Sciences (01-03-2011)“…The mammalian circadian timing system is organized into hierarchical structures with a central clock in the suprachiasmatic nucleus (SCN) and subsidiary…”
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The cryptochrome inhibitor KS15 enhances E-box-mediated transcription by disrupting the feedback action of a circadian transcription-repressor complex
Published in Life sciences (1973) (01-05-2018)“…We have previously identified a chemical scaffold possessing 2-ethoxypropanoic acid (designated as KS15) that directly binds to the C-terminal region of…”
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Cooperative roles of the suprachiasmatic nucleus central clock and the adrenal clock in controlling circadian glucocorticoid rhythm
Published in Scientific reports (12-04-2017)“…The mammalian circadian timing system consists of the central clock in the hypothalamic suprachiasmatic nucleus (SCN) and subsidiary peripheral clocks in other…”
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Multimodal Regulation of Circadian Glucocorticoid Rhythm by Central and Adrenal Clocks
Published in Journal of the Endocrine Society (01-05-2018)“…Abstract Adrenal glucocorticoids (GCs) control a wide range of physiological processes, including metabolism, cardiovascular and pulmonary activities, immune…”
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Identification of a novel circadian clock modulator controlling BMAL1 expression through a ROR/REV-ERB-response element-dependent mechanism
Published in Biochemical and biophysical research communications (15-01-2016)“…Circadian rhythms, biological oscillations with a period of about 24 h, are maintained by an innate genetically determined time-keeping system called the…”
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A synthetic cryptochrome inhibitor induces anti-proliferative effects and increases chemosensitivity in human breast cancer cells
Published in Biochemical and biophysical research communications (13-11-2015)“…Disruption of circadian rhythm is a major cause of breast cancer in humans. Cryptochrome (CRY), a circadian transcription factor, is a risk factor for…”
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Small Molecule Modulators of the Circadian Molecular Clock With Implications for Neuropsychiatric Diseases
Published in Frontiers in molecular neuroscience (21-01-2019)“…Circadian rhythms regulate many biological processes and play fundamental roles in behavior, physiology, and metabolism. Such periodicity is critical for…”
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Short-Term Depression at Thalamocortical Synapses Contributes to Rapid Adaptation of Cortical Sensory Responses In Vivo
Published in Neuron (Cambridge, Mass.) (25-04-2002)“…In vivo whole-cell recordings revealed that during repeated stimulation, synaptic responses to deflection of facial whiskers rapidly adapt. Extracellular…”
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Transcriptomic data of human adrenocortical NCI-H295R cells treated with cortisol biosynthesis inhibitors
Published in Data in brief (01-02-2024)“…Adrenal corticosteroid biosynthesis dysregulation can give rise to various pathological conditions, such as Cushing's syndrome, a disorder characterized by the…”
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Drug Abuse and Psychosis: New Insights into Drug-induced Psychosis
Published in Experimental neurobiology (01-02-2017)“…Addictive drug use or prescribed medicine abuse can cause psychosis. Some representative symptoms frequently elicited by patients with psychosis are…”
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How Microglia Manages Non-cell Autonomous Vicious Cycling of Aβ Toxicity in the Pathogenesis of AD
Published in Frontiers in molecular neuroscience (17-11-2020)“…Alzheimer's disease (AD) is a progressive neurodegenerative disease and a common form of dementia that affects cognition and memory mostly in aged people. AD…”
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Suppression of spontaneous activity before visual response in the primate V1 neurons during a visually guided saccade task
Published in The Journal of neuroscience (27-02-2013)“…Visually guided saccadic eye movements are thought to involve multiple stages of processing in diverse brain structures including the primary visual cortex…”
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