Search Results - "Chung, Kyung J."

Taxonomy of Fungi Causing Mucormycosis and Entomophthoramycosis (Zygomycosis) and Nomenclature of the Disease: Molecular Mycologic Perspectives by Kwon-Chung, Kyung J.

“…Molecular phylogenetic analysis confirmed the phylum Zygomycota to be polyphyietic, and the taxa conventionally classified in Zygomycota are now distributed…”
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Aspergillus fumigatus--what makes the species a ubiquitous human fungal pathogen? by Kwon-Chung, Kyung J, Sugui, Janyce A

“…  Since gliotoxin is immunosuppressive and cytocidal [17], it can be speculated that the fungus benefits from nutrients released by the gliotoxin-destroyed…”
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Do major species concepts support one, two or more species within Cryptococcus neoformans? by Kwon-Chung, Kyung J., Varma, Ashok

“…Abstract Cryptococcus neoformans, the agent of cryptococcosis, had been considered a homogeneous species until 1949 when the existence of four serotypes was…”
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Aneuploidy and drug resistance in pathogenic fungi by Kwon-Chung, Kyung J, Chang, Yun C

“…[...]reports of aneuploidy in pathogenic fungi linked to the emergence of drug resistance have been limited to FLC therapy, and studies of its mechanism have…”
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Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes by Sionov, Edward, Lee, Hyeseung, Chang, Yun C, Kwon-Chung, Kyung J

“…Cryptococcus neoformans is a haploid environmental organism and the major cause of fungal meningoencephalitis in AIDS patients. Fluconazole (FLC), a triazole,…”
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Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood–brain barrier by Maruvada, Ravi, Zhu, Longkun, Pearce, Donna, Zheng, Yi, Perfect, John, Kwon‐Chung, Kyung J., Kim, Kwang Sik

“…Summary Cryptococcus neoformans penetration into the central nervous system (CNS) requires traversal of the blood–brain barrier that is composed of a single…”
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Roles of Three Cryptococcus neoformans and Cryptococcus gattii Efflux Pump-Coding Genes in Response to Drug Treatment by Chang, Miwha, Sionov, Edward, Khanal Lamichhane, Ami, Kwon-Chung, Kyung J, Chang, Yun C

“…and species complexes are the etiologic agents of cryptococcosis. We have deciphered the roles of three ABC transporters, Afr1, Afr2, and Mdr1, in the…”
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Azole Heteroresistance in Cryptococcus neoformans: Emergence of Resistant Clones with Chromosomal Disomy in the Mouse Brain during Fluconazole Treatment by SIONOV, Edward, CHANG, Yun C, KWON-CHUNG, Kyung J

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans by Chang, Yun C, Bien, Clara M, Lee, Hyeseung, Espenshade, Peter J, Kwon-Chung, Kyung J

“…Cryptococcus neoformans is an environmental pathogen requiring atmospheric levels of oxygen for optimal growth. Upon inhalation, C. neoformans disseminates to…”
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Moderate levels of 5-fluorocytosine cause the emergence of high frequency resistance in cryptococci by Chang, Yun C., Lamichhane, Ami Khanal, Cai, Hongyi, Walter, Peter J., Bennett, John E., Kwon-Chung, Kyung J.

“…The antifungal agent 5-fluorocytosine (5-FC) is used for the treatment of several mycoses, but is unsuitable for monotherapy due to the rapid development of…”
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The primary target organ of Cryptococcus gattii is different from that of Cryptococcus neoformans in a murine model by Ngamskulrungroj, Popchai, Chang, Yun, Sionov, Edward, Kwon-Chung, Kyung J

“…Cryptococcosis is caused by the opportunistic pathogen Cryptococcus neoformans or by the primary pathogen Cryptococcus gattii. Epidemiological studies suggest…”
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Anti-granulocyte-macrophage colony-stimulating factor autoantibodies are a risk factor for central nervous system infection by Cryptococcus gattii in otherwise immunocompetent patients by Saijo, Tomomi, Chen, Jianghan, Chen, Sharon C-A, Rosen, Lindsey B, Yi, Jin, Sorrell, Tania C, Bennett, John E, Holland, Steven M, Browne, Sarah K, Kwon-Chung, Kyung J

“…Cryptococcosis is caused by either Cryptococcus neoformans or C. gattii. While cryptococcal meningoencephalitis is caused mostly by C. neoformans in…”
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A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands by Farrer, Rhys A, Chang, Miwha, Davis, Michael J, van Dorp, Lucy, Yang, Dong-Hoon, Shea, Terrance, Sewell, Thomas R, Meyer, Wieland, Balloux, Francois, Edwards, Hannah M, Chanda, Duncan, Kwenda, Geoffrey, Vanhove, Mathieu, Chang, Yun C, Cuomo, Christina A, Fisher, Matthew C, Kwon-Chung, Kyung J

“…We discovered a new lineage of the globally important fungal pathogen on the basis of analysis of six isolates collected from three locations spanning the…”
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Genetic relatedness versus biological compatibility between Aspergillus fumigatus and related species by Sugui, Janyce A, Peterson, Stephen W, Figat, Abigail, Hansen, Bryan, Samson, Robert A, Mellado, Emilia, Cuenca-Estrella, Manuel, Kwon-Chung, Kyung J

“…Aspergillus section Fumigati contains twelve clinically relevant species. Among them, A. fumigatus is the most frequent agent of invasive aspergillosis…”
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Involvement of PDK1, PKC and TOR signalling pathways in basal fluconazole tolerance in Cryptococcus neoformans by Lee, Hyeseung, Khanal Lamichhane, Ami, Garraffo, H. Martin, Kwon-Chung, Kyung J., Chang, Yun C.

“…Summary This study shows the importance of PDK1, TOR and PKC signalling pathways to the basal tolerance of Cryptococcus neoformans towards fluconazole, the…”
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Type I IFN Induction via Poly-ICLC Protects Mice against Cryptococcosis by Sionov, Edward, Mayer-Barber, Katrin D, Chang, Yun C, Kauffman, Keith D, Eckhaus, Michael A, Salazar, Andres M, Barber, Daniel L, Kwon-Chung, Kyung J

“…Cryptococcus neoformans is the most common cause of fungal meningoencephalitis in AIDS patients. Depletion of CD4 cells, such as occurs during advanced AIDS,…”
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Heteroresistance to Fluconazole in Cryptococcus neoformans Is Intrinsic and Associated with Virulence by SIONOV, Edward, CHANG, Yun C, GARRAFFO, H. Martin, KWON-CHUNG, Kyung J

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Population diversity and virulence characteristics of Cryptococcus neoformans/C. gattii species complexes isolated during the pre-HIV-pandemic era by Pharkjaksu, Sujiraphong, Kwon-Chung, Kyung J, Bennett, John E, Ngamskulrungroj, Popchai

“…Cryptococcosis has become a major global health problem since the advent of the HIV pandemic in 1980s. Although its molecular epidemiology is well-defined,…”
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Cryptococcus neoformans-derived microvesicles enhance the pathogenesis of fungal brain infection by Huang, Sheng-He, Wu, Chun-Hua, Chang, Yun C, Kwon-Chung, Kyung J, Brown, Robert J, Jong, Ambrose

“…Cryptococcal meningoencephalitis is the most common fungal disease in the central nervous system. The mechanisms by which Cryptococcus neoformans invades the…”
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Neutralizing GM-CSF autoantibodies in pulmonary alveolar proteinosis, cryptococcal meningitis and severe nocardiosis by Salvator, Hélène, Cheng, Aristine, Rosen, Lindsey B, Williamson, Peter R, Bennett, John E, Kashyap, Anuj, Ding, Li, Kwon-Chung, Kyung J, Namkoong, Ho, Zerbe, Christa S, Holland, Steven M

“…Abstract Background Anti GM-CSF autoantibodies (aAb) have been related to acquired pulmonary alveolar proteinosis (PAP) and described in cases of severe…”
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