Search Results - "Chung, Katherine Po Sin"

Overriding Adaptive Resistance to Sorafenib Through Combination Therapy With Src Homology 2 Domain–Containing Phosphatase 2 Blockade in Hepatocellular Carcinoma by Leung, Carmen Oi Ning, Tong, Man, Chung, Katherine Po Sin, Zhou, Lena, Che, Noélia, Tang, Kwan Ho, Ding, Jin, Lau, Eunice Yuen Ting, Ng, Irene Oi Lin, Ma, Stephanie, Lee, Terence Kin Wah

“…Background and Aims The survival benefit of sorafenib for patients with hepatocellular carcinoma (HCC) is unsatisfactory due to the development of adaptive…”
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Hampering Stromal Cells in the Tumor Microenvironment as a Therapeutic Strategy to Destem Cancer Stem Cells by Chung, Katherine Po Sin, Leung, Rainbow Wing Hei, Lee, Terence Kin Wah

“…Cancer stem cells (CSCs) within the tumor bulk play crucial roles in tumor initiation, recurrence and therapeutic resistance. In addition to intrinsic…”
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Catecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease by Kim, Hee-Hoon, Shim, Young-Ri, Choi, Sung Eun, Kim, Myung-Ho, Lee, Giljae, You, Hyun Ju, Choi, Won-Mook, Yang, Keungmo, Ryu, Tom, Kim, Kyurae, Kim, Min Jeong, Woo, Chaerin, Chung, Katherine Po Sin, Hong, Song Hwa, Eun, Hyuk Soo, Kim, Seok-Hwan, Ko, GwangPyo, Park, Jong-Eun, Gao, Bin, Kim, Won, Jeong, Won-Il

“…Chronic alcohol consumption often induces hepatic steatosis but rarely causes severe inflammation in Kupffer cells (KCs) despite the increased hepatic influx…”
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xCT-mediated glutamate excretion in white adipocytes stimulates interferon-γ production by natural killer cells in obesity by Kim, Hee-Hoon, Shim, Young-Ri, Kim, Ha Neul, Yang, Keungmo, Ryu, Tom, Kim, Kyurae, Choi, Sung Eun, Kim, Min Jeong, Woo, Chaerin, Chung, Katherine Po Sin, Hong, Song Hwa, Shin, Hyemi, Suh, Jae Myoung, Jung, Youngae, Hwang, Geum-Sook, Kim, Won, Kim, Seok-Hwan, Eun, Hyuk Soo, Seong, Je Kyung, Jeong, Won-Il

“…Obesity-mediated hypoxic stress underlies inflammation, including interferon (IFN)-γ production by natural killer (NK) cells in white adipose tissue. However,…”
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New insights in the pathogenesis of alcohol-related liver disease: The metabolic, immunologic, and neurologic pathways by Ryu, Tom, Kim, Kyurae, Choi, Sung Eun, Chung, Katherine Po Sin, Jeong, Won-Il

“…Alcohol-related liver disease (ALD) became an important health issue worldwide. Following chronic alcohol consumption, the development of ALD might be caused…”
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EPHB2 Activates β-Catenin to Enhance Cancer Stem Cell Properties and Drive Sorafenib Resistance in Hepatocellular Carcinoma by Leung, Hoi Wing, Leung, Carmen Oi Ning, Lau, Eunice Y, Chung, Katherine Po Sin, Mok, Etienne H, Lei, Martina Mang Leng, Leung, Rainbow Wing Hei, Tong, Man, Keng, Vincent W, Ma, Cong, Zhao, Qian, Ng, Irene Oi Lin, Ma, Stephanie, Lee, Terence K

“…The survival benefit derived from sorafenib treatment for patients with hepatocellular carcinoma (HCC) is modest due to acquired resistance. Targeting cancer…”
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CX 3 CR1 + macrophages interact with HSCs to promote HCC through CD8 + T-cell suppression by Jeong, Jong-Min, Choi, Sung Eun, Shim, Young-Ri, Kim, Hee-Hoon, Lee, Young-Sun, Yang, Keungmo, Kim, Kyurae, Kim, Min Jeong, Chung, Katherine Po Sin, Kim, Seok-Hwan, Byun, Jin-Seok, Eun, Hyuk Soo, Jeong, Won-Il

“…HSCs contribute to HCC progression by regulating multiple factors. However, the entire immunoregulatory functions of HSCs are still obscure. Here, we aim to…”
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CX3CR1+ macrophages interact with HSCs to promote HCC through CD8+ T-cell suppression by Jeong, Jong-Min, Choi, Sung Eun, Shim, Young-Ri, Kim, Hee-Hoon, Lee, Young-Sun, Yang, Keungmo, Kim, Kyurae, Kim, Min Jeong, Chung, Katherine Po Sin, Kim, Seok-Hwan, Byun, Jin-Seok, Eun, Hyuk Soo, Jeong, Won-Il

“…Background and Aims: HSCs contribute to HCC progression by regulating multiple factors. However, the entire immunoregulatory functions of HSCs are still…”
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Abstract 2799: Intestinal Akkermansia muciniphila complements the therapeutic efficacy of PD1 therapy by reshaping the immunosuppressive microenvironment in nonalcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma by Wu, Xueqian, Ying, Fan, Chung, Katherine Po Sin, Leung, Carmen Oi Ning, Lee, Terence Kin Wah

“…Abstract Objectives: Nonalcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma (HCC) is an emerging malignancy in the developed world. However,…”
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Emerging role of fatty acid binding proteins in cancer pathogenesis by Gurung, Shilpa, Chung, Katherine Po Sin, Lee, Terence Kin-Wah

“…Fatty acid binding proteins (FABPs) are 15-kDa proteins responsible for the transport of fatty acids both intracellularly and extracellularly. Consisting of 12…”
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Abstract 574: Adipocyte-derived FABP4 promotes non-alcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma by driving ITGB1-mediated β-catenin activation by Leung, Carmen Oi Ning, Gurung, Shilpa, Chung, Katherine Po Sin, Chan, Sze Man, Lee, Terence Kin Wah

“…Abstract Nonalcoholic fatty liver disease (NAFLD)-induced hepatocellular carcinoma (HCC) is an emerging malignancy in the developed countries. However, the…”
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