Search Results - "Chung, Haerim"
-
1
Recent advances in cellular immunotherapy for lymphoid malignancies
Published in Blood research (31-12-2023)“…Cellular immunotherapy with chimeric antigen receptor (CAR) T-cells has revolutionized the treatment of lymphoid malignancies. This review addresses the need…”
Get full text
Journal Article -
2
Cytogenetic testing by fluorescence in situ hybridization is improved by plasma cell sorting in multiple myeloma
Published in Scientific reports (18-05-2022)“…Accurate detection of cytogenetic abnormalities has become more important for improving risk-adapted treatment strategies in multiple myeloma (MM). However,…”
Get full text
Journal Article -
3
PERK/NRF2 and autophagy form a resistance mechanism against G9a inhibition in leukemia stem cells
Published in Journal of experimental & clinical cancer research (15-04-2020)“…The histone methyltransferase G9a has recently been identified as a potential target for epigenetic therapy of acute myeloid leukemia (AML). However, the…”
Get full text
Journal Article -
4
ULK1 inhibition as a targeted therapeutic strategy for FLT3-ITD-mutated acute myeloid leukemia
Published in Journal of experimental & clinical cancer research (11-05-2020)“…In acute myeloid leukemia (AML), internal tandem duplication mutations in the FLT3 tyrosine kinase receptor (FLT3-ITD) are associated with a dismal outcome…”
Get full text
Journal Article -
5
Long-Term Outcomes of COVID-19 and Risk Factors for Prolonged or Persistent COVID-19 in Lymphoma Patients: A Multicenter, Retrospective Cohort Study
Published in Journal of Korean medical science (28-10-2024)“…Patients with hematologic malignancies exhibit persistent severe acute respiratory syndrome coronavirus 2 positivity over long periods after coronavirus…”
Get full text
Journal Article -
6
Comprehensive insights into AML relapse: genetic mutations, clonal evolution, and clinical outcomes
Published in Cancer cell international (19-05-2024)“…Acute myeloid leukemia (AML) is a complex hematologic malignancy characterized by uncontrolled proliferation of myeloid precursor cells within bone marrow…”
Get full text
Journal Article -
7
Serum albumin and C-reactive protein as significant predictors of non-relapse mortality in lower gastrointestinal graft-versus-host disease
Published in Annals of hematology (01-05-2020)“…Acute graft-versus-host disease (aGVHD) of the lower gastrointestinal (GI) tract is the major cause of non-relapse mortality (NRM) in allogeneic hematopoietic…”
Get full text
Journal Article -
8
Upfront autologous hematopoietic stem cell transplantation for high-risk patients with double-expressor diffuse large B cell lymphoma
Published in Annals of hematology (01-09-2020)“…Although MYC and BCL2 co-expression in diffuse large B cell lymphoma (DLBCL) is associated with inferior prognosis, it remains uncertain whether upfront…”
Get full text
Journal Article -
9
Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature
Published in Journal of pathology and translational medicine (01-09-2020)“…Herein, we describe the first case of renal intravascular large B cell lymphoma in Korea occurring in a 66-year-old female. She presented with mild fever and…”
Get full text
Journal Article -
10
Clearing soluble MIC reverses the impaired function of natural killer cells from patients with multiple myeloma
Published in Journal for immunotherapy of cancer (08-01-2024)“…BackgroundMajor histocompatibility complex (MHC) class I chain-related protein (MIC) is a stress-induced ligand released from multiple myeloma (MM) cells…”
Get full text
Journal Article -
11
P851: ANTIBODY TARGETING OF SOLUBLE MHC‐CLASS‐I‐RELATED MOLECULE AUGMENTS NATURAL KILLER CELL FUNCTION BY RESTORING NKG2D IN MULTIPLE MYELOMA
Published in HemaSphere (08-08-2023)Get full text
Journal Article -
12
Arsenic trioxide synergistically promotes the antileukaemic activity of venetoclax by downregulating Mcl-1 in acute myeloid leukaemia cells
Published in Experimental hematology & oncology (15-04-2021)“…The evasion of apoptosis through dysregulated Bcl-2 family members is a hallmark of leukaemia stem cells (LSCs) in acute myeloid leukaemia (AML). Therefore,…”
Get full text
Journal Article -
13
Immunosuppressive role of CD11b+CD33+HLA‐DR− myeloid‐derived suppressor cells‐like blast subpopulation in acute myeloid leukemia
Published in Cancer medicine (Malden, MA) (01-10-2020)“…Objective Myeloid‐derived suppressor cells (MDSCs) facilitate tumor growth and development by suppressing T cell function; however, their role in acute myeloid…”
Get full text
Journal Article -
14
P800: CHARACTERIZATION OF REGULATORY T CELLS IN PATIENTS WITH MULTIPLE MYELOMA
Published in HemaSphere (08-08-2023)Get full text
Journal Article -
15
Different roles of surveillance positron emission tomography according to the histologic subtype of non-Hodgkin's lymphoma
Published in The Korean journal of internal medicine (01-03-2021)“…Although the use of surveillance 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is discouraged in patients with diffuse…”
Get full text
Journal Article -
16
Automation of 3D digital rolling circle amplification using a 3D-printed liquid handler
Published in Biosensors & bioelectronics (01-10-2024)“…Automation of liquid handling is indispensable to improve throughput and reproducibility in biochemical assays. However, the incorporation of automated systems…”
Get full text
Journal Article -
17
3D Amplified Single-Cell RNA and Protein Imaging Identifies Oncogenic Transcript Subtypes in B‑Cell Acute Lymphoblastic Leukemia
Published in ACS nano (06-02-2024)“…Simultaneous in situ detection of transcript and protein markers at the single-cell level is essential for gaining a better understanding of tumor…”
Get full text
Journal Article -
18
Clinical outcomes of etoposide and cytarabine as consolidation in elderly patients with primary CNS lymphoma
Published in The oncologist (Dayton, Ohio) (06-04-2024)“…A consolidation strategy has not been established for transplant-ineligible elderly patients with primary central nervous system lymphoma (PCNSL). In this…”
Get full text
Journal Article -
19
Adaptive Natural Killer Cells Facilitate Effector Functions of Daratumumab in Multiple Myeloma
Published in Clinical cancer research (15-05-2021)“…To investigate the different roles of heterogeneous natural killer (NK)-cell subpopulations in multiple myeloma and to identify NK-cell subsets that support…”
Get full text
Journal Article -
20
Single-Cell RNA Sequencing Identifies Distinct Immune Microenvironment in Patients with Primary Plasma Cell Leukemia
Published in Blood (02-11-2023)“…Background: Primary plasma cell leukemia (PCL) is a highly aggressive form of multiple myeloma (MM). While recent advances in cellular immunotherapy have…”
Get full text
Journal Article